WHAT IS ChIP and why is it useful?

ChIP immunoprecipitation (ChIP) is a method used to determine the location of DNA binding sites on the genome for a specific protein of interest, giving invaluable insights into the regulation of gene expression. ChIP is frequently used in studies that focus on cellular differentiation, tumor suppressor gene silencing, the effect of histone modifications on gene expression, and other studies involving transcriptional activation and repression.

Where do you want to begin?

Articles

• Why antibodies for ChIP matter
• Why chromatin shearing matters