Publications,References

Unisexual and heterosexual meiotic reproduction generate aneuploidy...
Published: September, 2013

Abstract: Aneuploidy is known to be deleterious and underlies several common human diseases, including cancer and genetic disorders such as trisomy 21 in Dow... Read more »

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DNA shearing Bioruptor

Histone deacetylase complex1 expression level titrates plant growth...
Published: September, 2013

Abstract: Histone deacetylation regulates gene expression during plant stress responses and is therefore an interesting target for epigenetic manipulation of... Read more »

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Antibody

miR-1/133a clusters cooperatively specify the cardiomyogenic lineag...
Published: September, 2013

Abstract: miRNAs are small RNAs directing many developmental processes by posttranscriptional regulation of protein-coding genes. We uncovered a new role for... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Antibody

A metagenomic snapshot of taxonomic and functional diversity in an ...
Published: September, 2013

Abstract: Cryoconite is a microbe–mineral aggregate which darkens the ice surface of glaciers. Microbial process and marker gene PCR-dependent measurements r... Read more »

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DNA shearing Bioruptor

Epigenetic silencing of Bim transcription by Spi-1/PU.1 promotes ap...
Published: September, 2013

Abstract: Deregulation of transcriptional networks contributes to haematopoietic malignancies. The transcription factor Spi-1/PU.1 is a master regulator of h... Read more »

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DNA shearing Bioruptor MeDIP kit

Mass production of SNP markers in a nonmodel passerine bird through...
Published: September, 2013

Abstract: Here, we present an adaptation of restriction-site-associated DNA sequencing (RAD-seq) to the Illumina HiSeq2000 technology that we used to produce... Read more »

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DNA shearing Bioruptor

Let-7b and miR-495 Stimulate Differentiation and Prevent Metaplasia...
Published: September, 2013

Abstract: BACKGROUND & AIMS: Diseases of the exocrine pancreas are often associated with perturbed differentiation of acinar cells. MicroRNAs (miRNAs) regula... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

The ASAP2 gene is a primary target of 1,25-dihydroxyvitamin D3 in h...
Published: August, 2013

Abstract: A genome-wide data set on vitamin D receptor (VDR) binding sites in human THP-1 cells (monocytes) led us to the genomic region around the ASAP2 (Ar... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus

Long range epigenetic silencing is a trans-species mechanism that r...
Published: August, 2013

Abstract: DNA methylation and chromatin remodeling are frequently implicated in the silencing of genes involved in carcinogenesis. Long Range Epigenetic Sile... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Antibody LowCell ChIP kit

Endogenous Nuclear RNAi Mediates Behavioral Adaptation to Odor.
Published: August, 2013

Abstract: Most eukaryotic cells express small regulatory RNAs. The purpose of one class, the somatic endogenous siRNAs (endo-siRNAs), remains unclear. Here, ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Transcriptional environment and chromatin architecture interplay di...
Published: August, 2013

Abstract: To explore the response of β globin locus with established chromatin domains upon their exposure to new transcriptional environments, we transferre... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

PRC2 Controls Drosophila Oocyte Cell Fate by Repressing Cell Cycle ...
Published: August, 2013

Abstract: The oocyte is a unique cell type that undergoes extensive chromosome changes on its way to fertilization, but the chromatin determinants of its fat... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Proteomics Strategies to Identify SUMO Targets and Acceptor Sites: ...
Published: August, 2013

Abstract: SUMOylation is a protein posttranslational modification that participates in the regulation of numerous biological processes within the cells. Smal... Read more »

A signature motif mediating selective interactions of BCL11A with t...
Published: August, 2013

Abstract: Despite their physiological importance, selective interactions between nuclear receptors (NRs) and their cofactors are poorly understood. Here, we ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Enhanced Chromatin Dynamics by FACT Promotes Transcriptional Restar...
Published: August, 2013

Abstract: Chromatin remodeling is tightly linked to all DNA-transacting activities. To study chromatin remodeling during DNA repair, we established quantitat... Read more »

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Bioruptor Chromatin Shearing

Optical control of mammalian endogenous transcription and epigeneti...
Published: August, 2013

Abstract: The dynamic nature of gene expression enables cellular programming, homeostasis and environmental adaptation in living systems. Dissection of causa... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

A GAA repeat expansion reporter model of Friedreich's ataxia recapi...
Published: August, 2013

Abstract: Friedreich's ataxia (FRDA) is caused by large GAA expansions in intron 1 of the frataxin gene (FXN), which lead to reduced FXN expression through a... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Conserved Regulators of Nucleolar Size Revealed by Global Phenotypi...
Published: August, 2013

Abstract: Regulation of cell growth is a fundamental process in development and disease that integrates a vast array of extra- and intracellular information.... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Sexually Dimorphic Genome-Wide Binding of Retinoid X Receptor alpha...
Published: August, 2013

Abstract: Many hepatic functions including lipid metabolism, drug metabolism, and inflammatory responses are regulated in a sex-specific manner due to distin... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus

PARP-1 Controls Immunosuppressive Function of Regulatory T Cells by...
Published: August, 2013

Abstract: Poly (ADP-ribose) polymerase-1 (PARP-1) is a nuclear enzyme and transcription factor that is involved in inflammatory response, but its role in T c... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

An In-Depth Characterization of the Major Psoriasis Susceptibility ...
Published: August, 2013

Abstract: Psoriasis is an immune-mediated skin disorder that is inherited as a complex genetic trait. Although genome-wide association scans (GWAS) have iden... Read more »

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Antibody

Genome-wide screening identifies Plasmodium chabaudi-induced modifi...
Published: August, 2013

Abstract: Epigenetic reprogramming of host genes via DNA methylation is increasingly recognized as critical for the outcome of diverse infectious diseases, b... Read more »

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Antibody MeDIP kit 5mC (C15200081)

Mutant IDH1 promotes leukemogenesis in vivo and can be specifically...
Published: August, 2013

Abstract: Mutations in the metabolic enzymes isocitrate dehydrogenase 1 (IDH1) and 2 (IDH2) are frequently found in glioma, acute myeloid leukemia (AML), mel... Read more »

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Bioruptor Cell Lysis Mass Spectrometry

Systematic Identification of Proteins Binding to Chromatin-Embedded...
Published: August, 2013

Abstract: Chromatin posttranslational modifications (PTMs), including monoubiquitylation of histone H2B on lysine 120 (H2Bub1), play a major role in regulati... Read more »

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Bioruptor Cell Lysis

CDK8-Mediated STAT1-S727 Phosphorylation Restrains NK Cell Cytotoxi...
Published: August, 2013

Abstract: The transcription factor STAT1 is important in natural killer (NK) cells, which provide immediate defense against tumor and virally infected cells.... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

WT1 regulates the expression of inhibitory chemokines during heart ...
Published: August, 2013

Abstract: The embryonic epicardium is an important source of cardiovascular precursor cells and paracrine factors that are required for adequate heart format... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Mod5 protein binds to tRNA gene complexes and affects local transcr...
Published: August, 2013

Abstract: The tRNA gene-mediated (tgm) silencing of RNA polymerase II promoters is dependent on subnuclear clustering of the tRNA genes, but genetic analysis... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Artd1/Parp1 regulates reprogramming by transcriptional regulation o...
Published: August, 2013

Abstract: The recently established reprogramming of somatic cells into induced pluripotent stem cells (iPSCs) by Takahashi and Yamanaka, represents a valuabl... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

A Kinase-Independent Function of CDK6 Links the Cell Cycle to Tumor...
Published: August, 2013

Abstract: In contrast to its close homolog CDK4, the cell cycle kinase CDK6 is expressed at high levels in lymphoid malignancies. In a model for p185(BCR-ABL... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Antibody H3K4me3 (C15410003)

Chromatin-Bound IκBα Regulates a Subset of Polycomb Target Genes in...
Published: August, 2013

Abstract: IκB proteins are the primary inhibitors of NF-κB. Here, we demonstrate that sumoylated and phosphorylated IκBα accumulates in the nucleus of kerati... Read more »

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