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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

HDAC1 Regulates Fear Extinction in Mice.
Published: April, 2012
Abstract: Histone acetylation has been implicated with the pathogenesis of neuropsychiatric disorders and targeting histone deacetylases (HDACs) using HDAC i... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Antibody
Miz1 Is a Critical Repressor of cdkn1a during Skin Tumorigenesis.
Published: April, 2012
Abstract: The transcription factor Miz1 forms repressive DNA-binding complexes with the Myc, Gfi-1 and Bcl-6 oncoproteins. Known target genes of these comple... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus
Gli1 participates in the hedgehog-mediated specification of the ost...
Published: April, 2012
Abstract: With regard to hedgehog (Hh) signaling in mammalian development, the majority of research has focused on Gli2 and Gli3 rather than Gli1. This is be... Read more »
Kruppel-like factor 15 regulates skeletal muscle lipid flux and exe...
Published: April, 2012
Abstract: The ability of skeletal muscle to enhance lipid utilization during exercise is a form of metabolic plasticity essential for survival. Conversely, m... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Yin Yang 1 Deficiency in Skeletal Muscle Protects against Rapamycin...
Published: April, 2012
Abstract: Rapamycin and its derivatives are mTOR inhibitors used in tissue transplantation and cancer therapy. A percentage of patients treated with these in... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Complete Chloroplast Genome Sequence of an Orchid Model Plant Candi...
Published: April, 2012
Abstract: Oncidium is an important ornamental plant but the study of its functional genomics is difficult. Erycina pusilla is a fast-growing Oncidiinae speci... Read more »
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DNA shearing Bioruptor Bioruptor Plus
The RNA-Binding Protein Human Antigen R Controls Global Changes in ...
Published: April, 2012
Abstract: An important prerequisite to myelination in peripheral nerves is the establishment of one-to-one relationships between axons and Schwann cells. Thi... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Fast Homozygosity Mapping and Identification of a Zebrafish ENU-Ind...
Published: April, 2012
Abstract: Forward genetics using zebrafish is a powerful tool for studying vertebrate development through large-scale mutagenesis. Nonetheless, the identific... Read more »
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DNA shearing Bioruptor
The histone methyltransferase ASH1 orchestrates fibrogenic gene tra...
Published: April, 2012
Abstract: BACKGROUND AND AIMS: Transdifferentiation of hepatic stellate cells (HSCs) to a myofibroblast-like phenotype is a pivotal event that drives liver f... Read more »
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Antibody
PPARgamma inhibits hepatocellular carcinoma metastases in vitro and...
Published: April, 2012
Abstract: Background:We have previously demonstrated that peroxisome proliferator-activated receptor (PPARγ) activation inhibits hepatocarcinogenesis. We aim... Read more »
Characterization of endolysin from a Salmonella Typhimurium-infecti...
Published: April, 2012
Abstract: The full genome sequence of bacteriophage SPN1S, which infects Salmonella, contains genes that encode homologues of holin, endolysin and Rz/Rz1-lik... Read more »
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Bioruptor Cell Lysis
A hindbrain-repressive Wnt3a/Meis3/Tsh1 circuit promotes neuronal d...
Published: April, 2012
Abstract: During development, early inducing programs must later be counterbalanced for coordinated tissue maturation. In Xenopus laevis embryos, activation ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Rev-erbα and Rev-erbβ coordinately protect the circadian clock and ...
Published: April, 2012
Abstract: The nuclear receptor Rev-erbα regulates circadian rhythm and metabolism, but its effects are modest and it has been considered to be a secondary re... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Cell Lysis
UV-sensitive syndrome protein UVSSA recruits USP7 to regulate trans...
Published: April, 2012
Abstract: Transcription-coupled nucleotide-excision repair (TC-NER) is a subpathway of NER that efficiently removes the highly toxic RNA polymerase II blocki... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
A GATA Transcription Factor Recruits Hda1 in Response to Reduced To...
Published: April, 2012
Abstract: Candida albicans is an important opportunistic fungal pathogen of immunocompromised individuals. One critical virulence attribute is its morphogene... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Frequent aberrant expression of the human ether à go-go (hEAG1) pot...
Published: March, 2012
Abstract: Compelling evidence indicates that the human ether-à-go-go voltage-gated potassium channels (hEAG1) may represent new valuable membrane therapeutic... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
ErbB2-Driven Breast Cancer Cell Invasion Depends on a Complex Signa...
Published: March, 2012
Abstract: Aberrant ErbB2 receptor tyrosine kinase activation in breast cancer is strongly linked to an invasive disease. The molecular basis of ErbB2-driven ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus
A synthetic biology approach to self-regulatory recombinant protein...
Published: March, 2012
Abstract: ABSTRACT: BACKGROUND: Recombinant protein production is a process of great industrial interest, with products that range from pharmaceuticals to bi... Read more »
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Bioruptor Cell Lysis Western Blot
hnRNP C tetramer measures RNA length to classify RNA polymerase II ...
Published: March, 2012
Abstract: Specific RNA recognition is usually achieved by specific RNA sequences and/or structures. However, we show here a mechanism by which RNA polymerase... Read more »
Sequential ChIP-bisulfite sequencing enables direct genome-scale in...
Published: March, 2012
Abstract: Cross-talk between DNA methylation and histone modifications drives the establishment of composite epigenetic signatures and is traditionally studi... Read more »
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DNA shearing Bioruptor Chromatin Shearing ChIP-seq Antibody
The lhx2 transcription factor controls thalamocortical axonal guida...
Published: March, 2012
Abstract: The assembly of neural circuits is dependent upon the generation of specific neuronal subtypes, each subtype displaying unique properties that dire... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Inflammasome-Activated Caspase 7 Cleaves PARP1 to Enhance the Expre...
Published: March, 2012
Abstract: Caspase 1 is part of the inflammasome, which is assembled upon pathogen recognition, while caspases 3 and/or 7 are mediators of apoptotic and nonap... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
The Histone Demethylase KDM1A Sustains the Oncogenic Potential of M...
Published: March, 2012
Abstract: Using a mouse model of human MLL-AF9 leukemia, we identified the lysine-specific demethylase KDM1A (LSD1 or AOF2) as an essential regulator of leuk... Read more »
DNA methylation dynamics, metabolic fluxes, gene splicing, and alte...
Published: March, 2012
Abstract: In honey bees (Apis mellifera), the development of a larva into either a queen or worker depends on differential feeding with royal jelly and invol... Read more »
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DNA shearing Bioruptor
Analysis of Chromatin Dynamics during Glucocorticoid Receptor Activ...
Published: March, 2012
Abstract: Steroid hormone receptors initiate a genetic program tightly regulated by the chromatin environment of the responsive regions. Using the glucocorti... Read more »
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Bioruptor Chromatin Shearing
A dual Role for the dREAM/MMB complex in the regulation of differen...
Published: March, 2012
Abstract: E2F and RB proteins regulate the expression of genes involved in cell cycle progression, apoptosis, differentiation, and development. Recent studie... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
DBIRD complex integrates alternative mRNA splicing with RNA polymer...
Published: March, 2012
Abstract: Alternative messenger RNA splicing is the main reason that vast mammalian proteomic complexity can be achieved with a limited number of genes. Spli... Read more »
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Bioruptor RNA Shearing
Low-Dose Cd Induces Hepatic Gene Hypermethylation, along with the P...
Published: March, 2012
Abstract: BACKGROUND: Cadmium (Cd) is classified as a human carcinogen probably associated with epigenetic changes. DNA methylation is one of epigenetic mech... Read more »
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DNA shearing Bioruptor
Deconstruction of the SS18-SSX fusion oncoprotein complex: insights...
Published: March, 2012
Abstract: Synovial sarcoma is a translocation-associated sarcoma where the underlying chromosomal event generates SS18-SSX fusion transcripts. In vitro and i... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus
Genetic and Epigenetic Determinants of Neurogenesis and Myogenesis.
Published: March, 2012
Abstract: The regulatory networks of differentiation programs have been partly characterized; however, the molecular mechanisms of lineage-specific gene regu... Read more »
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DNA shearing Bioruptor

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