Diagenode

Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

The histone H2B monoubiquitination regulatory pathway is required f...
Published: June, 2012

Abstract: Extensive changes in posttranslational histone modifications accompany the rewiring of the transcriptional program during stem cell differentiation... Read more »

Tags
Antibody H3K4me3 (C15410003) H3K27me3 (C15410069)
Genome-wide localization and expression profiling establish Sp2 as ...
Published: June, 2012

Abstract: The transcription factor Sp2 is essential for early mouse development and for proliferation of mouse embryonic fibroblasts in culture. Yet its mech... Read more »

Tags
Antibody
Recruitment of histone deacetylase 3 to the interferon-a gene promo...
Published: June, 2012

Abstract: BACKGROUND: Induction of Type I Interferon (IFN) genes constitutes an essential step leading to innate immune responses during virus infection. Sen... Read more »

Tags
Antibody
Transcriptional networks driving enhancer function in the CFTR gene.
Published: June, 2012

Abstract: A critical cis-regulatory element for the cystic fibrosis transmembrane conductance regulator (CFTR) gene is located in intron 11, 100 kb distal to... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus
GSK3 Temporally Regulates Neurogenin 2 Proneural Activity in the Ne...
Published: June, 2012

Abstract: The neocortex is comprised of six neuronal layers that are generated in a defined temporal sequence. While extrinsic and intrinsic cues are known t... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR
Developmentally non-redundant SET domain proteins SUVH2 and SUVH9 a...
Published: June, 2012

Abstract: In plants, RNA-directed DNA methylation (RdDM) and related transcriptional gene silencing (TGS) involve members of the suppressor of variegation 3-... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR
Genomics of DNA cytosine methylation in Escherichia coli reveals it...
Published: June, 2012

Abstract: DNA cytosine methylation regulates gene expression in mammals. In bacteria, its role in gene expression and genome architecture is less understood.... Read more »

Tags
DNA shearing Bioruptor
Intronic RNAs mediate EZH2 regulation of epigenetic targets.
Published: June, 2012

Abstract: Epigenetic deregulation at a number of genomic loci is one of the hallmarks of cancer. A role for some RNA molecules in guiding repressive polycomb... Read more »

Tags
Antibody LowCell ChIP kit H3K4me3 (C15410003) H3K27me3 (C15410069)
SUMO-targeted ubiquitin E3 ligase RNF4 is required for the response...
Published: June, 2012

Abstract: Here we demonstrate that RNF4, a highly conserved small ubiquitin-like modifier (SUMO)-targeted ubiquitin E3 ligase, plays a critical role in the r... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR
FOXO1 in the ventromedial hypothalamus regulates energy balance.
Published: June, 2012

Abstract: The transcription factor FOXO1 plays a central role in metabolic homeostasis by regulating leptin and insulin activity in many cell types, includin... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR
Histone H2B Ubiquitylation Promotes Activity of the Intact Set1 His...
Published: June, 2012

Abstract: The methylation of histone H3 at lysine 4 (H3K4me) is critical for the formation of transcriptionally active chromatin in eukaryotes. In yeast, Dro... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR
Genome structure-based screening identified epigenetically silenced...
Published: June, 2012

Abstract: MicroRNA (miRNA) expression is frequently altered in human cancers. To search for epigenetically silenced miRNAs in non-small-cell lung cancer (NSC... Read more »
Preferential Genome Targeting of the CBP Co-Activator by Rel and Sm...
Published: June, 2012

Abstract: CBP and the related p300 protein are widely used transcriptional co-activators in metazoans that interact with multiple transcription factors. Whet... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-seq
Overexpression of HGF attenuates the degeneration of Purkinje cells...
Published: June, 2012

Abstract: Spinocerebellar ataxia type 7 (SCA7) is an autosomal dominant disorder associated with cerebellar neurodegeneration caused by expansion of a CAG re... Read more »

Tags
Tissue Homogenization
Multiple Histone Methyl and Acetyltransferase Complex Components Bi...
Published: May, 2012

Abstract: Major histocompatibility complex class II (MHC-II) genes are fundamental components that contribute to adaptive immune responses. While characteriz... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR
Serum Response Factor and cAMP Response Element Binding Protein Are...
Published: May, 2012

Abstract: The molecular mechanism underlying induction by cocaine of ΔFosB, a transcription factor important for addiction, remains unknown. Here, we demonst... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR
Disruptive cell cycle regulation involving epigenetic downregulatio...
Published: May, 2012

Abstract: Cell cycle aberration was immunohistochemically examined in relation to preneoplastic liver cell foci expressing glutathione S-transferase placenta... Read more »

Tags
DNA shearing MeDIP kit
Genome-Wide Characterization of Menin-Dependent H3K4me3 Reveals a S...
Published: May, 2012

Abstract: Inactivating mutations in the MEN1 gene predisposing to the multiple endocrine neoplasia type 1 (MEN1) syndrome can also cause sporadic pancreatic ... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-seq
Myb-binding protein 1a (Mybbp1a) regulates levels and processing of...
Published: May, 2012

Abstract: Ribosomal RNA gene transcription, co-transcriptional processing and ribosome biogenesis are highly coordinated processes that are tightly regulated... Read more »

Tags
Bioruptor
Mus81-Mms4 function as a single heterodimer to cleave nicked interm...
Published: May, 2012

Abstract: The formation of crossovers is a fundamental genetic process. The XPF-family endonuclease, Mus81-Mms4 (Eme1), contributes significantly to crossing... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR
The aryl hydrocarbon receptor ligands 2,3,7,8-tetrachlorodibenzo-p-...
Published: May, 2012

Abstract: The two estrogen receptor isoforms ERα and ERβ mediate biological effects of estrogens, but are also targets for endocrine disruptive chemicals (ED... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR
Design, Synthesis, and Biological Evaluation of 2-Aminobenzanilide ...
Published: May, 2012

Abstract: Epigenetic regulation is an essential process for the normal functioning of genes. Therefore, targeting epigenetic dysregulation in cancer may be a... Read more »

Tags
Antibody
Epigenetic Repression of RARRES1 Is Mediated by Methylation of a Pr...
Published: May, 2012

Abstract: BACKGROUND: The cis-acting promoter element responsible for epigenetic silencing of retinoic acid receptor responder 1 (RARRES1) by methylation is ... Read more »

Tags
Antibody
Functional Genomic Methods to Study Estrogen Receptor Activity.
Published: May, 2012

Abstract: Estrogen Receptor (ER) is a nuclear receptor that mediates the actions of estrogen and tamoxifen. ER is expressed in a major fraction of human brea... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-seq Antibody
Dynamics of enhancer chromatin signatures mark the transition from ...
Published: May, 2012

Abstract: The generation of distinctive cell types that form different tissues and organs requires precise, temporal and spatial control of gene expression. ... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-seq Antibody
Evolution of Burkholderia pseudomallei in Recurrent Melioidosis.
Published: May, 2012

Abstract: Burkholderia pseudomallei, the etiologic agent of human melioidosis, is capable of causing severe acute infection with overwhelming septicemia lead... Read more »

Tags
DNA shearing Bioruptor
The Stat6-regulated KRAB domain zinc finger protein Zfp157 regulate...
Published: May, 2012

Abstract: Lineage commitment studies in mammary glands have focused on identifying cell populations that display stem or progenitor properties. However, the ... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus

Events

  • AACR 2024
    San Diego, California, USA
    Apr 5-Apr 10, 2024
 See all events

News

 See all news


The European Regional Development Fund and Wallonia are investing in your future.

Extension of industrial buildings and new laboratories.


       Site map   |   Contact us   |   Conditions of sales   |   Conditions of purchase   |   Privacy policy   |   Diagenode Diagnostics