MEF2C protects bone marrow B-lymphoid progenitors during stress haematopoiesis Published: August, 2016 Abstract:
DNA double strand break (DSB) repair is critical for generation of B-cell receptors, which are pre-requisite for B-cell progenitor survival. However, the transcription factors that promote DSB repair in B cells are not known. Here we show that MEF... Read more » Tags Antibody
Epigenetic dynamics of monocyte-to-macrophage differentiation Published: July, 2016 Abstract:
BACKGROUND:
Monocyte-to-macrophage differentiation involves major biochemical and structural changes. In order to elucidate the role of gene regulatory changes during this process, we used high-throughput sequencing to analyze the complete tran... Read more » Tags AntibodyIP-Star Compact
Osr1 Interacts Synergistically with Wt1 to Regulate Kidney Organogenesis Published: July, 2016 Abstract:
Renal hypoplasia is a common cause of pediatric renal failure and several adult-onset diseases. Recent studies have associated a variant of the OSR1 gene with reduction of newborn kidney size and function in heterozygotes and neonatal lethality wi... Read more » Tags Antibody
MEIS2 Is an Oncogenic Partner in AML1-ETO-Positive AML Published: July, 2016 Abstract:
Homeobox genes are known to be key factors in leukemogenesis. Although the TALE family homeodomain factor Meis1 has been linked to malignancy, a role for MEIS2 is less clear. Here, we demonstrate that MEIS2 is expressed at high levels in patients ... Read more » Tags Antibody
