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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Discovering hematopoietic mechanisms through genome-wide analysis o...
Published: November, 2009
Abstract: GATA factors interact with simple DNA motifs (WGATAR) to regulate critical processes, including hematopoiesis, but very few WGATAR motifs are occup... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
An oestrogen-receptor-alpha-bound human chromatin interactome.
Published: November, 2009
Abstract: Genomes are organized into high-level three-dimensional structures, and DNA elements separated by long genomic distances can in principle interact ... Read more »
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Antibody
The miR-124-Sox9 paramutation: RNA-mediated epigenetic control of e...
Published: November, 2009
Abstract: The size of the mammalian body is determined by genetic and environmental factors differentially modulating pre- and postnatal growth. We now repor... Read more »
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LowCell ChIP kit
Frequent long-range epigenetic silencing of protocadherin gene clus...
Published: November, 2009
Abstract: Wilms' tumour (WT) is a pediatric tumor of the kidney that arises via failure of the fetal developmental program. The absence of identifiable mutat... Read more »
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DNA shearing Bioruptor
Global analysis of H3K4 methylation defines MLL family member targe...
Published: November, 2009
Abstract: A common landmark of activated genes is the presence of trimethylation on lysine 4 of histone H3 (H3K4) at promoter regions. Set1/COMPASS was the f... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
The presence of RNA polymerase II, active or stalled, predicts epig...
Published: November, 2009
Abstract: Instructive mechanisms are present for induction of DNA methylation, as shown by methylation of specific CpG islands (CGIs) by specific inducers an... Read more »
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Antibody
Zinc finger transcription factor ecotropic viral integration site 1...
Published: November, 2009
Abstract: Ecotropic viral integration site 1 (EVI1) plays important roles in leukaemia and development, and its expression is temporally and spatially highly... Read more »
Antiangiogenic liposomal gene therapy with 16K human prolactin effi...
Published: November, 2009
Abstract: Human 16K PRL (16K hPRL) is a potent inhibitor of angiogenesis both in vitro and in vivo. It has been shown to prevent tumor growth in three xenogr... Read more »
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Master Mix
Sp1 mediate hypoxia induced ephrinB2 expression via a hypoxia-induc...
Published: October, 2009
Abstract: Environmental factors are instrumental in maintaining a healthy vasculature. Oxygen tension is higher in arteries than in veins and thus has the po... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
The NF-kappaB factor RelB and histone H3 lysine methyltransferase G...
Published: October, 2009
Abstract: The interplay of transcription factors, histone modifiers, and DNA modification can alter chromatin structure that epigenetically controls gene tra... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
JAK2 phosphorylates histone H3Y41 and excludes HP1alpha from chroma...
Published: October, 2009
Abstract: Activation of Janus kinase 2 (JAK2) by chromosomal translocations or point mutations is a frequent event in haematological malignancies. JAK2 is a ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
INTS3 controls the hSSB1-mediated DNA damage response.
Published: October, 2009
Abstract: Human SSB1 (single-stranded binding protein 1 [hSSB1]) was recently identified as a part of the ataxia telangiectasia mutated (ATM) signaling pathw... Read more »
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Bioruptor Cell Lysis Western Blot
The histone variant macroH2A is an epigenetic regulator of key deve...
Published: October, 2009
Abstract: The histone variants macroH2A1 and macroH2A2 are associated with X chromosome inactivation in female mammals. However, the physiological function o... Read more »
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Antibody H3K4me3 (C15410003)
Development of a novel output value for quantitative assessment in ...
Published: October, 2009
Abstract: In DNA methylation microarray analysis, quantitative assessment of intermediate methylation levels in samples with various global methylation level... Read more »
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Antibody
Smad3 is required for normal follicular follicle-stimulating hormon...
Published: October, 2009
Abstract: Follicle-stimulating hormone (FSH) is the major regulator of folliculogenesis, but other factors modulate its action, including members of the tran... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Sox3: a transcription factor for Cyp19 expression in the frog Rana ...
Published: September, 2009
Abstract: Cyp19 is expressed at a high level in the gonad of the female tadpole of the frog Rana rugosa during sex determination. To identify sequence elemen... Read more »
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LowCell ChIP kit
Foxa1 and Foxa2 function both upstream of and cooperatively with Lm...
Published: September, 2009
Abstract: Mesodiencephalic dopaminergic neurons control voluntary movement and reward based behaviours. Their dysfunction can lead to neurological disorders,... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Linking cell cycle to histone modifications: SBF and H2B monoubiqui...
Published: September, 2009
Abstract: To identify regulators involved in determining the differential pattern of H3K79 methylation by Dot1, we screened the entire yeast gene deletion co... Read more »
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Bioruptor Chromatin Shearing
p57Kip2 is a repressor of Mash1 activity and neuronal differentiati...
Published: September, 2009
Abstract: Mammalian central nervous system (CNS) development is a highly organized process involving the precise and coordinated timing of cell-cycle exit, d... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Plasmodium falciparum heterochromatin protein 1 marks genomic loci ...
Published: September, 2009
Abstract: Epigenetic processes are the main conductors of phenotypic variation in eukaryotes. The malaria parasite Plasmodium falciparum employs antigenic va... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Antibody
Functional connection between deimination and deacetylation of hist...
Published: September, 2009
Abstract: Histone methylation plays key roles in regulating chromatin structure and function. The recent identification of enzymes that antagonize or remove ... Read more »
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Bioruptor Chromatin Shearing Cell Lysis Antibody
A hierarchy of H3K4me3 and H3K27me3 acquisition in spatial gene reg...
Published: September, 2009
Abstract: Epigenetic mechanisms set apart the active and inactive regions in the genome of multicellular organisms to produce distinct cell fates during embr... Read more »
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Antibody
Three-dimensional structure of the two-peptide bacteriocin plantari...
Published: September, 2009
Abstract: The three-dimensional structures of the two peptides, PlnJ and PlnK, that constitutes the two-peptide bacteriocin plantaricin JK have been solved i... Read more »
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Bioruptor Liposome Preparation
Microarray-based multicycle-enrichment of genomic subsets for targe...
Published: September, 2009
Abstract: The lack of efficient high-throughput methods for enrichment of specific sequences from genomic DNA represents a key bottleneck in exploiting the e... Read more »
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DNA shearing Bioruptor
Phosphorylation of the transcription elongation factor Spt5 by yeas...
Published: September, 2009
Abstract: The Saccharomyces cerevisiae kinase Bur1 is involved in coupling transcription elongation to chromatin modification, but not all important Bur1 tar... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
The first Korean genome sequence and analysis: full genome sequenci...
Published: September, 2009
Abstract: We present the first Korean individual genome sequence (SJK) and analysis results. The diploid genome of a Korean male was sequenced to 28.95-fold ... Read more »
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DNA shearing Bioruptor
Transcription independent insulation at TFIIIC-dependent insulators.
Published: September, 2009
Abstract: Chromatin insulators separate active from repressed chromatin domains. In yeast the RNA pol III transcription machinery bound to tRNA genes functio... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
The multiple endocrine neoplasia type 1 (MEN1) tumor suppressor reg...
Published: September, 2009
Abstract: Menin, the product of the MEN1 (multiple endocrine neoplasia type 1) tumor suppressor gene, is involved in activation of gene transcription as part... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Characterization of glucocorticoid receptor and hepatocyte nuclear ...
Published: September, 2009
Abstract: Hepatocyte nuclear factor 4alpha (HNF4alpha) plays a crucial role in hepatocyte differentiation, liver organogenesis and regulation of liver functi... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Ultradian hormone stimulation induces glucocorticoid receptor-media...
Published: September, 2009
Abstract: Studies on glucocorticoid receptor (GR) action typically assess gene responses by long-term stimulation with synthetic hormones. As corticosteroids... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR

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