Publications,References

Alternative splicing of the histone demethylase LSD1/KDM1 contribut...
Published: February, 2010

Abstract: A variety of chromatin remodeling complexes are thought to orchestrate transcriptional programs that lead neuronal precursors from earliest commitm... Read more »

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Antibody

PML-RARalpha/RXR Alters the Epigenetic Landscape in Acute Promyeloc...
Published: February, 2010

Abstract: Many different molecular mechanisms have been associated with PML-RARalpha-dependent transformation of hematopoietic progenitors. Here, we identifi... Read more »

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IP-Star Antibody RARalpha (C15310155)

Chromatin remodeling by imitation switch (ISWI) class ATP-dependent...
Published: February, 2010

Abstract: ATP-dependent chromatin remodeling complexes rearrange nucleosomes by altering the position of DNA around the histone octamer. Although chromatin r... Read more »

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Antibody

AGRONOMICS1: a new resource for Arabidopsis transcriptome profiling.
Published: February, 2010

Abstract: Transcriptome profiling has become a routine tool in biology. For Arabidopsis (Arabidopsis thaliana), the Affymetrix ATH1 expression array is most ... Read more »

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Bioruptor Chromatin Shearing Antibody LowCell ChIP kit

Antiinflammatory properties of a plant-derived nonsteroidal, dissoc...
Published: February, 2010

Abstract: Compound A (CpdA), a plant-derived phenyl aziridine precursor, was recently characterized as a fully dissociated nonsteroidal antiinflammatory agen... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Human papillomavirus type 8 E2 protein unravels JunB/Fra-1 as an ac...
Published: February, 2010

Abstract: The papillomavirus life cycle parallels keratinocyte differentiation in stratifying epithelia. We have previously shown that the human papillomavir... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Potential role of estrogen in regulation of the insulin-like growth...
Published: January, 2010

Abstract: The selective estrogen receptor modulator, tamoxifen, has been shown to reduce DNA methylation at Insulin-like growth factor 2/H19 differentially m... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Epigenetic chromatin states uniquely define the developmental plast...
Published: January, 2010

Abstract: Heritable epigenetic signatures are proposed to serve as an important regulatory mechanism in lineage fate determination. To investigate this, we p... Read more »

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Bioruptor Chromatin Shearing

Early-life experience reduces excitation to stress-responsive hypot...
Published: January, 2010

Abstract: Increased sensory input from maternal care attenuates neuroendocrine and behavioral responses to stress long term and results in a lifelong phenoty... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Activation of Cdc6 by MyoD is associated with the expansion of quie...
Published: January, 2010

Abstract: MyoD is a transcriptional factor that is required for the differentiation of muscle stem cells (satellite cells). In this study, we describe a prev... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

FM19G11, a new hypoxia-inducible factor (HIF) modulator, affects st...
Published: January, 2010

Abstract: The biology of the alpha subunits of hypoxia-inducible factors (HIFalpha) has expanded from their role in angiogenesis to their current position in... Read more »

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LowCell ChIP kit

Cardiac signaling genes exhibit unexpected sequence diversity in sp...
Published: January, 2010

Abstract: Sporadic heart failure is thought to have a genetic component, but the contributing genetic events are poorly defined. Here, we used ultra-high-thr... Read more »

Unlocking short read sequencing for metagenomics.
Published: January, 2010

Abstract: BACKGROUND: Different high-throughput nucleic acid sequencing platforms are currently available but a trade-off currently exists between the cost a... Read more »

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DNA shearing Bioruptor

Polycomb target genes are silenced in multiple myeloma.
Published: January, 2010

Abstract: Multiple myeloma (MM) is a genetically heterogeneous disease, which to date remains fatal. Finding a common mechanism for initiation and progressio... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

A comprehensive map of insulator elements for the Drosophila genome.
Published: January, 2010

Abstract: Insulators are DNA sequences that control the interactions among genomic regulatory elements and act as chromatin boundaries. A thorough understand... Read more »

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Bioruptor Chromatin Shearing

Sole-Search: an integrated analysis program for peak detection and ...
Published: January, 2010

Abstract: Next-generation sequencing is revolutionizing the identification of transcription factor binding sites throughout the human genome. However, the bi... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Differential DNA methylation correlates with differential expressio...
Published: January, 2010

Abstract: Epigenetic mechanisms such as microRNA and histone modification are crucially responsible for dysregulated gene expression in heart failure. In con... Read more »

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DNA shearing Bioruptor

Rapid, low-input, low-bias construction of shotgun fragment librari...
Published: January, 2010

Abstract: We characterize and extend a highly efficient method for constructing shotgun fragment libraries in which transposase catalyzes in vitro DNA fragme... Read more »

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DNA shearing Bioruptor

A Method to Study the Epigenetic Chromatin States of Rare Hematopoi...
Published: January, 2010

Abstract: Dynamic chromatin structure is a fundamental property of gene transcriptional regulation, and has emerged as a critical modulator of physiological... Read more »

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Bioruptor Chromatin Shearing

Genome-wide analysis of aberrant methylation in human breast cancer...
Published: January, 2010

Abstract: BACKGROUND: Cancer cells undergo massive alterations to their DNA methylation patterns that result in aberrant gene expression and malignant phenot... Read more »

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Antibody

The epigenetic landscape of latent Kaposi sarcoma-associated herpes...
Published: January, 2010

Abstract: Herpesvirus latency is generally thought to be governed by epigenetic modifications, but the dynamics of viral chromatin at early timepoints of lat... Read more »

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DNA shearing Bioruptor Chromatin Shearing Antibody

In vivo chromatin organization of mouse rod photoreceptors correlat...
Published: January, 2010

Abstract: BACKGROUND: The folding of genetic information into chromatin plays important regulatory roles in many nuclear processes and particularly in gene t... Read more »

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Antibody

The core binding factor CBF negatively regulates skeletal muscle te...
Published: January, 2010

Abstract: BACKGROUND: Core Binding Factor or CBF is a transcription factor composed of two subunits, Runx1/AML-1 and CBF beta or CBFbeta. CBF was originally ... Read more »

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Bioruptor Antibody

UPF2 is a critical regulator of liver development, function and reg...
Published: January, 2010

Abstract: BACKGROUND: Nonsense-mediated mRNA decay (NMD) is a post-transcriptional RNA surveillance process that facilitates the recognition and destruction ... Read more »

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Antibody

The Runx transcriptional co-activator, CBFbeta, is essential for in...
Published: January, 2010

Abstract: BACKGROUND: The transcription factor Runx2 has an established role in cancers that metastasize to bone. In metastatic breast cancer cells Runx2 is ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

A paucity of heterochromatin at functional human neocentromeres.
Published: January, 2010

Abstract: BACKGROUND: Centromeres are responsible for the proper segregation of replicated chromatids during cell division. Neocentromeres are fully function... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

An NF-kappaB-dependent role for JunB in the induction of proinflamm...
Published: January, 2010

Abstract: BACKGROUND: Dendritic cells (DCs) play a key role in the induction of adaptive and memory immune responses. Upon encounter with pathogens, they und... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Monovalent and unpoised status of most genes in undifferentiated ce...
Published: January, 2010

Abstract: BACKGROUND: Increasing evidence demonstrates that stem cells maintain their identities by a unique transcription network and chromatin structure. O... Read more »

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DNA shearing Bioruptor

Retinoic acid protects human breast cancer cells against etoposide-...
Published: January, 2010

Abstract: BACKGROUND: Retinoids, through their cognate nuclear receptors, exert potent effects on cell growth, differentiation and apoptosis, and have signif... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Genome-wide conserved consensus transcription factor binding motifs...
Published: January, 2010

Abstract: BACKGROUND: DNA methylation can regulate gene expression by modulating the interaction between DNA and proteins or protein complexes. Conserved con... Read more »

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DNA shearing Bioruptor Antibody

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