Diagenode

Antibody Applications

siRNA Knockdown

Epigenetic antibodies you can trust!

Antibody quality is essential for assay success. Diagenode offers antibodies that are actually validated and have been widely used and published by the scientific community. Now we are adding a new level of siRNA knockdown validation to assure the specificity of our non-histone antibodies.

Short interfering RNA (siRNA) degrades target mRNA, followed by the knock-down of protein production. If the antibody that recognizes the protein of interest is specific, the Western blot of siRNA-treated cells will show a significant reduction of signal vs. untreated cells.

WB results obtained with the HDAC1 pAb (Cat. No. C15100144)
on siRNA transfected cells (lane 2) and on untransfected control cells (lane 1).

Epigenetic success guaranteed

The below list shows our first siRNA validated antibodies. More results - coming soon.

Validated by siRNA Knockdown

Cat. No.ProductFormatPrice
C15410210-50 CTCF polyclonal antibody - Classic
Alternative name: MRD21 Polyclonal antibody raised in rabbit against human CTCF (CCCTC-Binding Factor), using 4 KLH coupled peptides.
50 μg $305.00
C15410039-50 EZH2 polyclonal antibody - Classic
Other names: ENX-1, ENX1, KMT6, KMT6A, WVS, WVS2 Polyclonal antibody raised in rabbit against the N-terminus (aa1-343) of the mouse EZH2 protein (Enhan...
50 µg $305.00
C15100144 HDAC1 monoclonal antibody - Classic
Alternative names: HD1, RPD3, RPD3L1, GON-10 Monoclonal antibody raised in mouse against human HDAC1 (Histone deacetylase 1), using a KLH-conjugated synthet...
100 µl $305.00
C15200144 HDAC1 monoclonal antibody - Classic
Alternative names: HD1, RPD3, RPD3L1, GON-10 Monoclonal antibody raised in mouse against human HDAC1 (Histone deacetylase 1), using a KLH-conjugated synthet...
50 μg/25 μl $305.00
C15410325-50 HDAC1 polyclonal antibody - Premium
Alternative names: HD1, RPD3, RPD3L1, GON-10 Polyclonal antibody raised in rabbit against the C-terminal region of human HDAC1 (Histone deacetylase 1), usin...
50 μg $390.00
C15200201 HDAC2 monoclonal antibody - Classic
Alternative names: HD2, RPD3, YAF1 Monoclonal antibody raised in mouse against human HDAC2 (Histone deacetylase 2), using a KLH-conjugated synthetic peptide...
50 μg $305.00
C15410028 LSD1 polyclonal antibody - Classic
Alternative names: BHC110, AOF2, EC1, KDM1 Polyclonal antibody raised in rabbit against human LSD1 (Lysine-specific demethylase 1), using the full length re...
50 µg/25µl $305.00
C15410067 LSD1 polyclonal antibody - Classic
Alternative names: BHC110, AOF2, EC1, KDM1 Polyclonal antibody raised in rabbit against human LSD1 (Lysine-specific demethylase 1), using a KLH-conjugated s...
50 µg $305.00
C15310028 LSD1 polyclonal antibody - Pioneer
Alternative names: BHC110, AOF2, EC1, KDM1 Polyclonal antibody raised in rabbit against human LSD1 (Lysine-specific demethylase 1), using the full length re...
100 µl $200.00
C15410052 MeCP2 polyclonal antibody - Classic
Alternative names: AUTSX3, MRX16, MRX79, MRXS13, MRXSL, PPMX, RTS, RTT Polyclonal antibody raised in rabbit against MeCP2 (Methyl-CpG-binding domain protein...
50 µg/42 µl $305.00
C15100055-100 Pol II monoclonal antibody - Classic
Alternative names: POLR2A, RPB1, POLR2, RPOL2 Monoclonal antibody raised in mouse against the B1 subunit of RNA polymerase II (polymerase (RNA) II (DNA dire...
100 µl $305.00
C15200004 Pol II monoclonal antibody - Classic
Alternative names: POLR2A, RPB1, POLR2, RPOL2 Monoclonal antibody raised in mouse against the YSPTSPS repeat in the B1 subunit of RNA polymerase II. 
50 μg $305.00
C15200005-50 Pol II S2p monoclonal antibody - Classic
Alternative names: POLR2A, RPB1, POLR2, RPOL2 Monoclonal antibody raised in mouse against the YSPTSPS repeat in the B1 subunit of RNA polymerase II, phospho...
50 μg $305.00
C15200007-50 Pol II S5p monoclonal antibody - Classic
Alternative names: POLR2A, RPB1, POLR2, RPOL2 Monoclonal antibody raised in mouse against the YSPTSPS repeat in the B1 subunit of RNA polymerase II, phospho...
50 μg $305.00
C15200002 TBP monoclonal antibody - Classic
Alternative names: GTF2D, GTF2D1, SCA17, TF2D, TFIID Monoclonal antibody raised in mouse against the amino-terminal domain of human TBP (TATA box binding pr...
100 µg $305.00

Events

  • The 12th Annual Meeting of the Japanese Society for Epigenetics
    Jun 24-Jun 25, 2018
  • PEMED 2018 Personalized and Precision Medecine
    Asiem Paris France
    Jun 25-Jun 27, 2018
  • FAANG Training school on ChIP-seq
    Wageningen
    Jun 25-Jun 29, 2018
  • Ecole Thematique FieldEpiGen
    Perpignan
    Jun 25-Jun 29, 2018
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Applications

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