DNA hydroxymethylation control package

5-Hydroxymethylation highlights the heterogeneity in keratinization andcell junctions in head and neck cancers.
Liu, Siyu and de Medeiros, Marcell Costa and Fernandez, Evan M and Zarins,Katie R and Cavalcante, Raymond G and Qin, Tingting and Wolf, Gregory T andFigueroa, Maria E and D'Silva, Nisha J and Rozek, Laura S and Sartor,Maureen A
BACKGROUND: Head and neck squamous cell carcinoma (HNSCC) is the sixth most prevalent cancer worldwide, with human papillomavirus (HPV)-related HNSCC rising to concerning levels. Extensive clinical, genetic and epigenetic differences exist between HPV-associated HNSCC and HPV-negative HNSCC, which is often linked to...