DNA hydroxymethylation control package

Catalog Number
48 rxns

The DNA hydroxymethylation control package includes one hydroxymethylated spike-in control and its corresponding qPCR primer set that can be added to the DNA sample of interest for any hydroxymethylation profiling experiment (e.g. with Diagenode's hMeDIP Kit).

CAUTION: The hydroxymethylated spike-in control is produced from a genomic sequence from Arabidopsis thaliana and may therefore interfere with plant samples. However, it does not show significant homology with other samples species (e.g. human, mouse or rat).

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    5-Hydroxymethylation highlights the heterogeneity in keratinization andcell junctions in head and neck cancers.
    Liu, Siyu and de Medeiros, Marcell Costa and Fernandez, Evan M and Zarins,Katie R and Cavalcante, Raymond G and Qin, Tingting and Wolf, Gregory T andFigueroa, Maria E and D'Silva, Nisha J and Rozek, Laura S and Sartor,Maureen A
    BACKGROUND: Head and neck squamous cell carcinoma (HNSCC) is the sixth most prevalent cancer worldwide, with human papillomavirus (HPV)-related HNSCC rising to concerning levels. Extensive clinical, genetic and epigenetic differences exist between HPV-associated HNSCC and HPV-negative HNSCC, which is often linked to...

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