Diagenode

Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

From Human Monocytes to Genome-Wide Binding Sites - A Protocol for ...
Published: April, 2014

Abstract: Chromatin immunoprecipitation in combination with a genome-wide analysis via high-throughput sequencing is the state of the art method to gain geno... Read more »

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Microplex Library Preparation kit
Suv39h1 mediates AP-2α-dependent inhibition of C/EBPα expression du...
Published: April, 2014

Abstract: Previous studies show that CCAAT/enhancer-binding protein α (C/EBPα) plays a very important role during adipocyte terminal differentiation and that... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Glycolytic genes are targets of the nuclear receptor Ad4BP/SF-1.
Published: April, 2014

Abstract: Genetic deficiencies in transcription factors can lead to the loss of certain types of cells and tissue. The steroidogenic tissue-specific nuclear ... Read more »

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Bioruptor Chromatin Shearing ChIP-seq Bioruptor Plus
Acupuncture Promotes Angiogenesis after Myocardial Ischemia through...
Published: April, 2014

Abstract: BACKGROUND: Acupuncture exerts cardioprotective effects on several types of cardiac injuries, especially myocardial ischemia (MI), but the mechanis... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Histone Deacetylase 1 and p300 Can Directly Associate with Chromati...
Published: April, 2014

Abstract: Lysine acetyltransferases (KATs) and histone deacetylases (HDACs) are important epigenetic modifiers and dynamically cycled on active gene promoter... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Rif1 controls DNA replication timing in yeast through the PP1 phosp...
Published: April, 2014

Abstract: The Rif1 protein, originally identified as a telomere-binding factor in yeast, has recently been implicated in DNA replication control from yeast t... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Epigenetic upregulation of corticotrophin-releasing hormone mediate...
Published: April, 2014

Abstract: Accumulating evidences demonstrated that early postnatal maternal separation induced remarkable social and memory defects in the adult rodents. Ear... Read more »

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DNA shearing Bioruptor Chromatin Shearing ChIP-qPCR
ZBED6 Modulates the Transcription of Myogenic Genes in Mouse Myobla...
Published: April, 2014

Abstract: ZBED6 is a recently discovered transcription factor, unique to placental mammals, that has evolved from a domesticated DNA transposon. It acts as a... Read more »

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Bioruptor Chromatin Shearing ChIP-seq
Characterization of an archaeal two-component system that regulates...
Published: April, 2014

Abstract: Two-component signal transduction systems (TCSs) are a major mechanism used by bacteria in response to environmental changes. Although many sequenc... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus
The transcription factor E4bp4/Nfil3 controls commitment to the NK ...
Published: April, 2014

Abstract: The transcription factor E4bp4 (Nfil3) is essential for natural killer (NK) cell production. Here, we show that E4bp4 is required at the NK lineage... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Multisite phosphorylation of the Sum1 transcriptional repressor by ...
Published: April, 2014

Abstract: Activation of the meiotic transcription factor Ndt80 is a key regulatory transition in the life-cycle of Saccharomyces cerevisiae because it trigge... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Whole Exome Sequencing Identifies Recessive PKHD1 Mutations in a Ch...
Published: April, 2014

Abstract: BACKGROUND: Mutations in PKHD1 cause autosomal recessive Caroli disease, which is a rare congenital disorder involving cystic dilatation of the int... Read more »

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DNA shearing Bioruptor
Comparative epigenomics in distantly related teleost species identi...
Published: April, 2014

Abstract: The complex relationship between ontogeny and phylogeny has been the subject of attention and controversy since von Baer's formulations in the 19th... Read more »

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Bioruptor Chromatin Shearing ChIP-seq Antibody
YY1 Acts as a Transcriptional Activator of Hoxa5 Gene Expression in...
Published: April, 2014

Abstract: The Hox gene family encodes homeodomain-containing transcriptional regulators that confer positional information to axial and paraxial tissues in t... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
TAL effector-mediated genome visualization (TGV).
Published: April, 2014

Abstract: The three-dimensional remodeling of chromatin within nucleus is being recognized as determinant for genome regulation. Recent technological advance... Read more »

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Antibody
Protein quantitative trait Loci identify novel candidates modulatin...
Published: April, 2014

Abstract: Annotating and interpreting the results of genome-wide association studies (GWAS) remains challenging. Assigning function to genetic variants as ex... Read more »

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Bioruptor Cell Lysis
USP7 attenuates hepatic gluconeogenesis through modulation of FoxO1...
Published: April, 2014

Abstract: Hepatic forkhead protein FoxO1 is a key component of systemic glucose homeostasis via its ability to regulate the transcription of rate-limiting en... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Intronic DNA elements regulate Nrf-2 chemical responsiveness of the...
Published: April, 2014

Abstract: In humans, microsomal epoxide hydrolase (mEH) contributes important biological functions that underlie both detoxification and bioactivation fates ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
ApoER2 processing by presenilin-1 modulates reelin expression.
Published: April, 2014

Abstract: The reelin signaling protein and its downstream components have been associated with synaptic plasticity and neurotransmission. The reelin signalin... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
LORD-Q: a long-run real-time PCR-based DNA-damage quantification me...
Published: April, 2014

Abstract: DNA damage is tightly associated with various biological and pathological processes, such as aging and tumorigenesis. Although detection of DNA dam... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Length-dependent processing of telomeres in the absence of telomerase.
Published: April, 2014

Abstract: In the absence of telomerase, telomeres progressively shorten with every round of DNA replication, leading to replicative senescence. In telomerase... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
CpG domains downstream of TSSs promote high levels of gene expression.
Published: April, 2014

Abstract: CpG dinucleotides are known to play a crucial role in regulatory domains, affecting gene expression in their natural context. Here, we demonstrate ... Read more »

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Bioruptor Chromatin Shearing
The antineoplastic effect of carnosine is accompanied by induction ...
Published: April, 2014

Abstract: Carnosine (β-alanyl-L-histidine) is a naturally occurring dipeptide that shows antineoplastic effects in cell culture as well as in animal experime... Read more »

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Bioruptor Cell Lysis
Alterations of the lung methylome in allergic airway hyper-responsi...
Published: April, 2014

Abstract: Asthma is a chronic airway disorder characterized by recurrent attacks of breathlessness and wheezing, affecting 300 million people around the worl... Read more »

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MethylCap
Differential RISC association of endogenous human microRNAs predict...
Published: April, 2014

Abstract: It has previously been assumed that the generally high stability of microRNAs (miRNAs) reflects their tight association with Argonaute (Ago) protei... Read more »

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Antibody
Suppression of intragenic transcription requires the MOT1 and NC2 r...
Published: April, 2014

Abstract: Chromatin structure in transcribed regions poses a barrier for intragenic transcription. In a comprehensive study of the yeast chromatin remodelers... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Folic acid stimulation of neural stem cell proliferation is associa...
Published: April, 2014

Abstract: Proliferation of neural stem cells (NSCs) is required for development and repair in the nervous system. NSC amplification in vitro is a necessary s... Read more »

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DNA shearing Bioruptor Antibody
Mapping of six somatic linker histone H1 variants in human breast c...
Published: April, 2014

Abstract: Seven linker histone H1 variants are present in human somatic cells with distinct prevalence across cell types. Despite being key structural compon... Read more »

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Bioruptor Chromatin Shearing ChIP-seq IPure kit
Transcriptional Derepression of the ERVWE1 Locus following Influenz...
Published: April, 2014

Abstract: UNLABELLED: Syncytin-1, a fusogenic protein encoded by a human endogenous retrovirus of the W family (HERV-W) element (ERVWE1), is expressed in the... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Antibody
Detecting authorized and unauthorized genetically modified organism...
Published: April, 2014

Abstract: The growing number of biotech crops with novel genetic elements increasingly complicates the detection of genetically modified organisms (GMOs) in ... Read more »

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Master Mix

Events

  • 14th International Symposium on Minimal Residual Cancer
    Nice, France
    May 7-May 9, 2025
  • 23rd BioPharma Drug Discovery Nexus
    San Francisco
    May 7-May 8, 2025
  • QMUL Centre for Epigenetics Launch Conference 2025
    London, UK
    Jun 4, 2025
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