Publications,References

Minimal, encapsulated proteomic-sample processing applied to copy-n...
Published: March, 2014

Abstract: Mass spectrometry (MS)-based proteomics typically employs multistep sample-preparation workflows that are subject to sample contamination and loss.... Read more »

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Bioruptor Cell Lysis

Epigenetics of prostate cancer: distribution of histone H3K27me3 bi...
Published: March, 2014

Abstract: Prostate cancer is the second most common cause of cancer and the sixth leading cause of cancer fatalities in men world- wide (Ferlay et al., 2010)... Read more »

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IP-Star Antibody H3K27me3 (C15410069)

Stage-specific control of early B cell development by the transcrip...
Published: March, 2014

Abstract: The transcription factor Ikaros is an essential regulator of lymphopoiesis. Here we studied its B cell-specific function by conditional inactivatio... Read more »

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Bioruptor Chromatin Shearing ChIP-seq Antibody H3K4me3 (C15410003)

FoxA1 directs the lineage and immunosuppressive properties of a nov...
Published: March, 2014

Abstract: The defective generation or function of regulatory T (Treg) cells in autoimmune disease contributes to chronic inflammation and tissue injury. We r... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus

Centromeric histone H2B monoubiquitination promotes noncoding trans...
Published: March, 2014

Abstract: Functional centromeres are essential for proper cell division. Centromeres are established largely by epigenetic processes resulting in incorporati... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus

The chromatin regulator Brg1 suppresses formation of intraductal pa...
Published: March, 2014

Abstract: Pancreatic ductal adenocarcinoma (PDA) develops through distinct precursor lesions, including pancreatic intraepithelial neoplasia (PanIN) and intr... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Nascent chromatin capture proteomics determines chromatin dynamics ...
Published: March, 2014

Abstract: To maintain genome function and stability, DNA sequence and its organization into chromatin must be duplicated during cell division. Understanding ... Read more »

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Bioruptor Chromatin Shearing

Sequencing and assembly of the 22-gb loblolly pine genome.
Published: March, 2014

Abstract: Conifers are the predominant gymnosperm. The size and complexity of their genomes has presented formidable technical challenges for whole-genome sh... Read more »

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DNA shearing Bioruptor

BMP4 promotes EMT and mesodermal commitment in human embryonic stem...
Published: March, 2014

Abstract: Bone morphogenetic proteins (BMPs) initiate differentiation in human embryonic stem cells (hESCs) but the exact mechanisms have not been fully eluc... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Live cell imaging unveils multiple domain requirements for in vivo ...
Published: March, 2014

Abstract: Glucocorticoids are essential for life, but are also implicated in disease pathogenesis and may produce unwanted effects when given in high doses. ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

PGC7 suppresses TET3 for protecting DNA methylation.
Published: March, 2014

Abstract: Ten-eleven translocation (TET) family enzymes convert 5-methylcytosine to 5-hydroxylmethylcytosine. However, the molecular mechanism that regulates... Read more »

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DNA shearing Bioruptor

Perinatal exposure to low-dose bisphenol A affects the neuroendocri...
Published: March, 2014

Abstract: Bisphenol A (BPA) is an estrogen-mimicking endocrine disruptor. Early-life exposures to low doses of BPA exert long-lasting effects on animals' rep... Read more »

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Antibody

Characterization of two different Asf1 histone chaperones with dist...
Published: March, 2014

Abstract: The anti-silencing function protein 1 (Asf1) is a chaperone that forms a complex with histones H3 and H4 facilitating dimer deposition and removal ... Read more »

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Bioruptor Cell Lysis Western Blot

The 5p12 breast cancer susceptibility locus affects MRPS30 expressi...
Published: March, 2014

Abstract: Genome-wide association studies have identified numerous loci linked to breast cancer susceptibility, but the mechanism by which variations at thes... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

FRA2 is a STAT5 target gene regulated by IL-2 in human CD4 T cells.
Published: February, 2014

Abstract: Signal transducers and activators of transcription 5(STAT5) are cytokine induced signaling proteins, which regulate key immunological processes, su... Read more »

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LowCell ChIP kit

A recently evolved class of alternative 3'-terminal exons involved ...
Published: February, 2014

Abstract: Alternative 3'-terminal exons, which use intronic polyadenylation sites, are generally less conserved and expressed at lower levels than the last e... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Broadly permissive intestinal chromatin underlies lateral inhibitio...
Published: February, 2014

Abstract: Cells differentiate when transcription factors bind accessible cis-regulatory elements to establish specific gene expression programs. In different... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Mutant astrocytes differentiated from Rett syndrome patients-specif...
Published: February, 2014

Abstract: The disease mechanism of Rett syndrome (RTT) is not well understood. Studies in RTT mouse models have suggested a non-cell-autonomous role for astr... Read more »

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Antibody

Epigenomic alterations define lethal CIMP-positive ependymomas of i...
Published: February, 2014

Abstract: Ependymomas are common childhood brain tumours that occur throughout the nervous system, but are most common in the paediatric hindbrain. Current s... Read more »

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Bioruptor Chromatin Shearing ChIP-seq Antibody H3K27me3 (C15410069)

Pharmacological inhibition of EZH2 as a promising differentiation t...
Published: February, 2014

Abstract: Background Embryonal Rhabdomyosarcoma (RMS) is a pediatric soft-tissue sarcoma derived from myogenic precursors that is characterized by a good p... Read more »

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Antibody

Maintenance of Heterochromatin Boundary and Nucleosome Composition ...
Published: February, 2014

Abstract: Chromatin remodeling complexes cooperate to regulate gene promoters and to define chromatin neighborhoods. Here, we identified genetic and function... Read more »

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Bioruptor Chromatin Shearing

Epigenetic upregulation of endogenous VEGF-A reduces myocardial inf...
Published: February, 2014

Abstract: "Epigenetherapy" alters epigenetic status of the targeted chromatin and modifies expression of the endogenous therapeutic gene. In this study we us... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Antibody

Epigenetics of Human Myometrium: DNA Methylation of Genes Encoding ...
Published: February, 2014

Abstract: Preterm birth involves the interaction of societal and environmental factors potentially modulating the length of gestation via the epigenome. An e... Read more »

Sequencing-based large-scale genomics approaches with small numbers...
Published: February, 2014

Abstract: High-throughput sequencing has become the large-scale approach of choice to study global gene expression and the distribution of specific chromatin... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Reversible Top1 cleavage complexes are stabilized strand-specifical...
Published: February, 2014

Abstract: Various topological constraints at the ribosomal DNA (rDNA) locus impose an extra challenge for transcription and DNA replication, generating const... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

The FOS transcription factor family differentially controls trophob...
Published: February, 2014

Abstract: Extravillous trophoblast invasion is a fundamental component of human placentation. Invading trophoblast cells promote blood flow to the conceptus ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Myc and max genome-wide binding sites analysis links the Myc regula...
Published: February, 2014

Abstract: Myc is a master transcription factor that has been demonstrated to be required for embryonic stem cell (ESC) pluripotency, self-renewal, and inhibi... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Epigenetics meets genetics in acute myeloid leukemia: clinical impa...
Published: February, 2014

Abstract: PURPOSE: Molecular risk stratification of acute myeloid leukemia (AML) is largely based on genetic markers. However, epigenetic changes, including ... Read more »

Geriatric muscle stem cells switch reversible quiescence into senes...
Published: February, 2014

Abstract: Regeneration of skeletal muscle depends on a population of adult stem cells (satellite cells) that remain quiescent throughout life. Satellite cell... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR LowCell ChIP kit

Runx1t1 (Runt-related transcription factor 1; translocated to, 1) e...
Published: February, 2014

Abstract: BACKGROUND: Microglia, the resident immune cells of the brain, undergo rapid proliferation and produce several proinflammatory molecules and nitric... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

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