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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Concerted activities of distinct H4K20 methyltransferases at DNA do...
Published: July, 2014
Abstract: Although selective binding of 53BP1 to dimethylated histone H4 lysine 20 (H4K20me2) at DNA double-strand breaks (DSBs) is a necessary and pivotal d... Read more »
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Bioruptor Chromatin Shearing
DNA Break Mapping Reveals Topoisomerase II Activity Genome-Wide.
Published: July, 2014
Abstract: Genomic DNA is under constant assault by endogenous and exogenous DNA damaging agents. DNA breakage can represent a major threat to genome integrit... Read more »
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DNA shearing Bioruptor
Homozygous missense variant in the human CNGA3 channel causes cone-...
Published: July, 2014
Abstract: We assessed a large consanguineous Pakistani family (PKAB157) segregating early onset low vision problems. Funduscopic and electroretinographic eva... Read more »
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DNA shearing Bioruptor
Genome-Wide Characterization of Light-Regulated Genes in Neurospora...
Published: July, 2014
Abstract: The filamentous fungus Neurospora crassa responds to light in complex ways. To thoroughly study the transcriptional response of this organism to li... Read more »
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DNA shearing Bioruptor
DAB2IP regulates cancer stem cell phenotypes through modulating ste...
Published: July, 2014
Abstract: Cancer stem cell (CSC), the primary source of cancer-initiating population, is involved in cancer recurrence and drug-resistant phenotypes. This st... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Activating germline mutations in STAT3 cause early-onset multi-orga...
Published: July, 2014
Abstract: Monogenic causes of autoimmunity provide key insights into the complex regulation of the immune system. We report a new monogenic cause of autoimmu... Read more »
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DNA shearing Bioruptor
Changes in histone methylation and acetylation during microspore re...
Published: July, 2014
Abstract: In response to stress treatments, microspores can be reprogrammed to become totipotent cells that follow an embryogenic pathway producing haploid a... Read more »
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Antibody
Loss of neuronal 3D chromatin organization causes transcriptional a...
Published: July, 2014
Abstract: The interior of the neuronal cell nucleus is a highly organized three-dimensional (3D) structure where regions of the genome that are linearly mill... Read more »
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Bioruptor Chromatin Shearing ChIP-seq Antibody
An AUG Codon Conserved for Protein Function Rather than Translation...
Published: July, 2014
Abstract: Elk1 belongs to the ternary complex (TCF) subfamily of the ETS-domain transcription factors. Several studies have implicated an important function ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Eaf5/7/3 form a functionally independent NuA4 submodule linked to R...
Published: July, 2014
Abstract: The NuA4 histone acetyltransferase complex is required for gene regulation, cell cycle progression, and DNA repair. Dissection of the 13-subunit co... Read more »
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Bioruptor Chromatin Shearing
Genomic organization and evolution of double minutes/homogeneously ...
Published: July, 2014
Abstract: The mechanism for generating double minutes chromosomes (dmin) and homogeneously staining regions (hsr) in cancer is still poorly understood. Throu... Read more »
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DNA shearing Bioruptor
Development of a lentivirus vector-based assay for non-destructive ...
Published: July, 2014
Abstract: Cell-to-cell fusion can be quantified by endowing acceptor and donor cells with latent reporter genes/proteins and activators of these genes/protei... Read more »
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Antibody
PHD and TFIIS-Like Domains of the Bye1 Transcription Factor Determi...
Published: July, 2014
Abstract: The BYpass of Ess1 (Bye1) protein is a putative S. cerevisiae transcription factor homologous to the human cancer-associated PHF3/DIDO family of pr... Read more »
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Antibody
The active enhancer network operated by liganded RXR supports angio...
Published: July, 2014
Abstract: RXR signaling is predicted to have a major impact in macrophages, but neither the biological consequence nor the genomic basis of its ligand activa... Read more »
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Master Mix
Heat shock factor 2 is a stress-responsive mediator of neuronal mig...
Published: July, 2014
Abstract: Fetal alcohol spectrum disorder (FASD) is a frequent cause of mental retardation. However, the molecular mechanisms underlying brain development de... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Genome-wide analysis of DNA methylation patterns in horse
Published: July, 2014
Abstract: Background DNA methylation is an epigenetic regulatory mechanism that plays an essential role in mediating biological processes and determining ph... Read more »
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MagMeDIP kit
Heat shock factor 2 is a stress-responsive mediator of neuronal mig...
Published: July, 2014
Abstract: Fetal alcohol spectrum disorder (FASD) is a frequent cause of mental retardation. However, the molecular mechanisms underlying brain development de... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Gambogic acid inhibits multiple myeloma mediated osteoclastogenesis...
Published: July, 2014
Abstract: Bone disease, characterized by the presence of lytic lesions and osteoporosis is the hallmark of multiple myeloma (MM). Stromal cell-derived factor... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
K-Lysine acetyltransferase 2a regulates a hippocampal gene expressi...
Published: July, 2014
Abstract: Neuronal histone acetylation has been linked to memory consolidation, and targeting histone acetylation has emerged as a promising therapeutic stra... Read more »
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LowCell ChIP kit
IGF2BP1 Expression in Human Mesenchymal Stem Cells Significantly Af...
Published: July, 2014
Abstract: Mesenchymal stem cells (MSCs) are a population of cells harboring in many tissues with the ability to differentiate toward many different lineages.... Read more »
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MeDIP kit
Genome-wide association analysis of eosinophilic esophagitis provid...
Published: July, 2014
Abstract: Eosinophilic esophagitis (EoE) is a chronic inflammatory disorder associated with allergic hypersensitivity to food. We interrogated >1.5 millio... Read more »
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IP-Star IP-Star Compact
Screening and identification of small molecule inhibitors of ErbB2-...
Published: July, 2014
Abstract: ERBB2 amplification and overexpression are strongly associated with invasive cancer with high recurrence and poor prognosis. Enhanced ErbB2 signali... Read more »
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Bioruptor Cell Lysis
Comparative genome sequencing reveals chemotype-specific gene clust...
Published: July, 2014
Abstract: Background The fungal genus Stachybotrys produces several diverse toxins that affect human health. Its strains comprise two mutually-exclusive tox... Read more »
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DNA shearing Bioruptor
Paradoxical role of DNA methylation in activation of FoxA2 gene exp...
Published: July, 2014
Abstract: The transcription factor FoxA2 is a master regulator of endoderm development and pancreatic beta cell gene expression. To elucidate the mechanisms ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus
Microsatellite Primers for the Fungi Rhizopogon kretzerae and R. sa...
Published: July, 2014
Abstract: PREMISE OF THE STUDY: Rhizopogon kretzerae and R. salebrosus (Rhizopogonaceae) are ectomycorrhizal fungi symbiotic with pines and the mycoheterotr... Read more »
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DNA shearing Bioruptor
Noncoding Transcription by Alternative RNA Polymerases Dynamically ...
Published: July, 2014
Abstract: The eukaryotic epigenome is shaped by the genome topology in three-dimensional space. Dynamic reversible variations in this epigenome structure dir... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR IP-Star Bioruptor Plus IPure kit IP-Star Compact
Non-Circadian Expression Masking Clock-Driven Weak Transcription Rh...
Published: July, 2014
Abstract: U2OS cells harbor a circadian clock but express only a few rhythmic genes in constant conditions. We identified 3040 binding sites of the circadian... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Very small deletions within the NESP55 gene in pseudohypoparathyroi...
Published: July, 2014
Abstract: Pseudohypoparathyroidism (PHP) is caused by reduced expression of genes within the GNAS cluster, resulting in parathormone resistance. The cluster ... Read more »
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DNA shearing Bioruptor
FUS is sequestered in nuclear aggregates in ALS patient fibroblasts.
Published: July, 2014
Abstract: Mutations in the RNA-binding protein FUS have been shown to cause the neurodegenerative disease amyotrophic lateral sclerosis. We investigate wheth... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
bPeaks: a bioinformatics tool to detect transcription factor bindin...
Published: July, 2014
Abstract: Peak calling is a critical step in ChIPseq data analysis. Choosing the correct algorithm as well as optimized parameters for a specific biological ... Read more »
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Bioruptor Chromatin Shearing ChIP-seq

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