Publications,References

A simple method for the parallel deep sequencing of full influenza ...
Published: December, 2011

Abstract: Given the major threat of influenza A to human and animal health, and its ability to evolve rapidly through mutation and reassortment, tools that e... Read more »

Tags
DNA shearing Bioruptor

Etsrp/Etv2 Is Directly Regulated by Foxc1a/b in the Zebrafish Angio...
Published: December, 2011

Abstract: Rationale:Endothelial cells are developmentally derived from angioblasts specified in the mesodermal germ cell layer. The transcription factor etsr... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR

Mechanisms and functions of Tet protein-mediated 5-methylcytosine o...
Published: December, 2011

Abstract: Ten-eleven translocation 1-3 (Tet1-3) proteins have recently been discovered in mammalian cells to be members of a family of DNA hydroxylases that ... Read more »

Tags
Antibody

Novel insights into the regulation of antioxidant-response-element-...
Published: December, 2011

Abstract: A central mechanism in cellular defence against oxidative or electrophilic stress is mediated by transcriptional induction of genes via the ARE (an... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR

Role of farnesoid X receptor (FXR) in the process of differentiatio...
Published: December, 2011

Abstract: Bone tissue contains bile acids which accumulate from serum and which can be released in large amounts in the bone microenvironment during bone res... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR

Notch1 binds and induces degradation of Snail in hepatocellular car...
Published: November, 2011

Abstract: BACKGROUND: Hepatocellular carcinoma (HCC) is a common, highly invasive malignant tumor associated with a high mortality rate. We previously report... Read more »

Tags
Bioruptor Cell Lysis Enzymatic Assay

Systematic comparison of three methods for fragmentation of long-ra...
Published: November, 2011

Abstract: Next Generation Sequencing (NGS) technologies are gaining importance in the routine clinical diagnostic setting. It is thus desirable to simplify t... Read more »

Tags
DNA shearing Bioruptor

Distinct Epigenomic Features in End-Stage Failing Human Hearts
Published: November, 2011

Abstract: Background—The epigenome refers to marks on the genome, including DNA methylation and histone modifications, that regulate the expression of underl... Read more »

Tags
DNA shearing Bioruptor Chromatin Shearing ChIP-seq Antibody

Generation and characterization of rat and mouse monoclonal antibod...
Published: November, 2011

Abstract: Methyl CpG binding protein 2 (MeCP2) binds DNA, and has a preference for methylated CpGs and, hence, in cells, it accumulates in heterochromatin. E... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR

Epigenetic inactivation of paired box gene 5, a novel tumor suppres...
Published: November, 2011

Abstract: Using genome-wide methylation screening, we identified that paired box gene 5 (PAX5) is involved in human cancer development. However, the function... Read more »

Expression profile of the sphingosine kinase signalling system in t...
Published: November, 2011

Abstract: AIMS: Chronic obstructive pulmonary disease (COPD) is a leading cause of death worldwide. Despite its importance, treatment methods are limited and... Read more »

Tags
Bioruptor Cell Lysis Enzymatic Assay

Genomic Maps of Long Noncoding RNA Occupancy Reveal Principles of R...
Published: November, 2011

Abstract: Long noncoding RNAs (lncRNAs) are key regulators of chromatin state, yet the nature and sites of RNA-chromatin interaction are mostly unknown. Here... Read more »

Tags
Bioruptor Chromatin Shearing

Prostacyclin Synthase Expression and Epigenetic Regulation in Nonsm...
Published: November, 2011

Abstract: BACKGROUND: Prostacyclin synthase (PGIS) metabolizes prostaglandin H(2), into prostacyclin. This study aimed to determine the expression profile o... Read more »

Pre-B cell to macrophage transdifferentiation without significant p...
Published: November, 2011

Abstract: Transcription factor-induced lineage reprogramming or transdifferentiation experiments are essential for understanding the plasticity of differenti... Read more »

Tags
Antibody MethylCap

Human tRNA genes function as chromatin insulators
Published: November, 2011

Abstract: nsulators help separate active chromatin domains from silenced ones. In yeast, gene promoters act as insulators to block the spread of Sir and HP1 ... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR

The forkhead transcription factor FOXK2 promotes AP-1-mediated tran...
Published: November, 2011

Abstract: The transcriptional control circuitry in eukaryotic cells is complex and is orchestrated by combinatorially acting transcription factors. Forkhead ... Read more »

Tags
Bioruptor Chromatin Shearing

FOG-1 and GATA-1 act sequentially to specify definitive megakaryocy...
Published: November, 2011

Abstract: The transcription factors that control lineage specification of haematopoietic stem cells (HSCs) have been well described for the myeloid and lymph... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR

YY1 associates with the macrosatellite DXZ4 on the inactive X chrom...
Published: November, 2011

Abstract: DXZ4 is an X-linked macrosatellite composed of 12-100 tandemly arranged 3-kb repeat units. In females, it adopts opposite chromatin arrangements at... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR

Gene expression and epigenetic changes by furan in rat liver.
Published: November, 2011

Abstract: Furan, a widely used industrial compound, has been found in a number of heated food items. Furan is carcinogenic to rats and mice, but the mechanis... Read more »

Tags
MagMeDIP kit

Rapid mapping and identification of mutations in Caenorhabditis ele...
Published: November, 2011

Abstract: Forward genetic screens provide a powerful approach for inferring gene function on the basis of the phenotypes associated with mutated genes. Howev... Read more »

Tags
DNA shearing Bioruptor

Osteocalcin gene expression is regulated by wild-type p53.
Published: November, 2011

Abstract: The tumor-suppressor p53 is a transcription factor that regulates a number of genes in the process of cell-cycle inhibition, apoptosis, and DNA dam... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus

Down-Regulation of the Histone Methyltransferase EZH2 Contributes t...
Published: November, 2011

Abstract: Differentiation of human endometrial stromal cells (HESC) into decidual cells represents a highly coordinated process essential for embryo implanta... Read more »

Tags
Bioruptor Chromatin Shearing

Bivalent histone modifications in stem cells poise miRNA loci for C...
Published: November, 2011

Abstract: It has been proposed that the existence of stem cell epigenetic patterns confer a greater likelihood of CpG island hypermethylation on tumor suppre... Read more »

Tags
Antibody LowCell ChIP kit

PcG complexes set the stage for epigenetic inheritance of gene sile...
Published: November, 2011

Abstract: Polycomb group (PcG) proteins are part of a conserved cell memory system that conveys epigenetic inheritance of silenced transcriptional states thr... Read more »

Tags
Antibody

DNA methylation in liver tumorigenesis in fish from the environment
Published: November, 2011

Abstract: Read more »

Tags
MagMeDIP kit

Pharmacodynamics of curcumin as DNA hypomethylation agent in restor...
Published: November, 2011

Abstract: Prostate cancer (PCa) is one of the most deadly malignancies among men in the United States. Although localized prostate cancer can be effectively ... Read more »

Tags
DNA shearing Bioruptor

Low-dose paclitaxel ameliorates fibrosis in the remnant kidney mode...
Published: November, 2011

Abstract: Transforming growth factor (TGF)-β has been shown to play a central role in the development of tubulointerstitial fibrosis, which can be corrected ... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR

The draft genome and transcriptome of Cannabis sativa.
Published: October, 2011

Abstract: ABSTRACT: BACKGROUND: Cannabis sativa has been cultivated throughout human history as a source of fiber, oil and food, and for its medicinal and i... Read more »

Tags
DNA shearing Bioruptor

Tumor suppressor protein p53 recruits human Sin3B/HDAC1 complex for...
Published: October, 2011

Abstract: Master regulator protein p53, popularly known as the "guardian of genome" is the hub for regulation of diverse cellular pathways. Depending on the ... Read more »

Tags
Bioruptor Chromatin Shearing ChIP-qPCR

The oxidized thiol proteome in fission yeast--optimization of an IC...
Published: October, 2011

Abstract: Major intracellular disulfide formation is prevented in the cytosol by potent reducing systems. However, protein thiols can be oxidized as a conseq... Read more »

Tags
Bioruptor Cell Lysis Mass Spectrometry

Publications

Events

News