The Bioruptor® uses a gentle method of sonication to retain the integrity of DNA and/or biological complexes, including chromatin, protein-protein binding, protein-DNA complexes, and other biochemical and biological assay systems. The Bioruptor® Sonication System uses a waterbath to generate these indirect sonication waves, which emanate from an ultrasound element below the water tank. Because the system is gentler than other sonicators, many customers report better and more consistent results with the Bioruptor® than with harsher sonication methods. Multiple closed tubes can be sonicated together and the continuous rotation of tubes allows even distribution of the energy for efficient sonication. The Bioruptor® enables automation of sonication, guaranteeing higher reproducibility of results.