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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

SMRT long reads and Direct Label and Stain optical maps allow the g...
Published: November, 2018
Abstract: Background: The barn swallow (Hirundo rustica) is a migratory bird that has been the focus of a large number of ecological, behavioural and genetic... Read more »
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Megaruptor
Developmental origins of transgenerational sperm DNA methylation ep...
Published: November, 2018
Abstract: Epigenetic alterations in the germline can be triggered by a number of different environmental factors from diet to toxicants. These environmentall... Read more »
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Antibody
Deletion of an intronic HIF-2α binding site suppresses hypoxia-indu...
Published: November, 2018
Abstract: Hypoxia-inducible factors (HIFs) play a key role in the adaptation to low oxygen by interacting with hypoxia response elements (HREs) in the genome... Read more »
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Antibody
Aryl Hydrocarbon Receptor Signaling Cell Intrinsically Inhibits Int...
Published: November, 2018
Abstract: Innate lymphoid cells (ILCs) are important for mucosal immunity. The intestine harbors all ILC subsets, but how these cells are balanced to achieve... Read more »
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iDeal ChIP-seq Kit for Transcription Factors
Inhibiting Inflammation with Myeloid Cell-Specific Nanobiologics Pr...
Published: November, 2018
Abstract: Inducing graft acceptance without chronic immunosuppression remains an elusive goal in organ transplantation. Using an experimental transplantation... Read more »
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Antibody
Improved reference genome of Aedes aegypti informs arbovirus vector...
Published: November, 2018
Abstract: Female Aedes aegypti mosquitoes infect more than 400 million people each year with dangerous viral pathogens including dengue, yellow fever, Zika a... Read more »
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Megaruptor
Sensitive tumour detection and classification using plasma cell-fre...
Published: November, 2018
Abstract: The use of liquid biopsies for cancer detection and management is rapidly gaining prominence. Current methods for the detection of circulating tumo... Read more »
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MagMeDIP kit Antibody IPure kit
Integrative Proteomic Profiling Reveals PRC2-Dependent Epigenetic C...
Published: November, 2018
Abstract: The pluripotent ground state is defined as a basal state free of epigenetic restrictions, which influence lineage specification. While naive embryo... Read more »
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Antibody
A Lamina-Associated Domain Border Governs Nuclear Lamina Interactio...
Published: November, 2018
Abstract: Tcrb locus V(D)J recombination is regulated by positioning at the nuclear periphery. Here, we used DamID to profile Tcrb locus interactions with th... Read more »
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Bioruptor
RRAD, IL4I1, CDKN1A, and SERPINE1 genes are potentially co-regulate...
Published: November, 2018
Abstract: BACKGROUND: The cellular response to ionizing radiation involves activation of p53-dependent pathways and activation of the atypical NF-κB pa... Read more »
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Antibody iDeal ChIP-seq Kit for Transcription Factors
Whole-genome landscape of Medicago truncatula symbiotic genes.
Published: November, 2018
Abstract: Advances in deciphering the functional architecture of eukaryotic genomes have been facilitated by recent breakthroughs in sequencing technologies,... Read more »
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Megaruptor
Chromosome-scale assemblies of plant genomes using nanopore long re...
Published: November, 2018
Abstract: Plant genomes are often characterized by a high level of repetitiveness and polyploid nature. Consequently, creating genome assemblies for plant ge... Read more »
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Megaruptor
TIP60: an actor in acetylation of H3K4 and tumor development in bre...
Published: November, 2018
Abstract: AIM: The acetyltransferase TIP60 is reported to be downregulated in several cancers, in particular breast cancer, but the molecular mechanisms resu... Read more »
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IP-Star Compact
TET2 inhibits tumorigenesis of breast cancer cells by regulating ca...
Published: November, 2018
Abstract: Epigenetic regulators have been shown to influence breast cancer progression. However, the detailed mechanism by which TET2 plays the suppressive r... Read more »
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Antibody
Genome-wide identification of RETINOBLASTOMA RELATED 1 binding site...
Published: November, 2018
Abstract: Retinoblastoma (pRb) is a multifunctional regulator, which was likely present in the last common ancestor of all eukaryotes. The Arabidopsis pRb ho... Read more »
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Microplex Library Preparation kit
Transcription Factors Drive Tet2-Mediated Enhancer Demethylation to...
Published: November, 2018
Abstract: Here, we report DNA methylation and hydroxymethylation dynamics at nucleotide resolution using C/EBPα-enhanced reprogramming of B cells into ... Read more »
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Antibody
Sequentially acting SOX proteins orchestrate astrocyte- and oligode...
Published: November, 2018
Abstract: SOX transcription factors have important roles during astrocyte and oligodendrocyte development, but how glial genes are specified and activated in... Read more »
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Antibody
TRPS1 Is a Lineage-Specific Transcriptional Dependency in Breast Ca...
Published: October, 2018
Abstract: Perturbed epigenomic programs play key roles in tumorigenesis, and chromatin modulators are candidate therapeutic targets in various human cancer t... Read more »
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Antibody
SUMO Safeguards Somatic and Pluripotent Cell Identities by Enforcin...
Published: October, 2018
Abstract: Understanding general principles that safeguard cellular identity should reveal critical insights into common mechanisms underlying specification o... Read more »
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Antibody Microplex Library Preparation kit
RbAp48 Protein Is a Critical Component of GPR158/OCN Signaling and ...
Published: October, 2018
Abstract: Precisely deciphering the molecular mechanisms of age-related memory loss is crucial to create appropriate therapeutic interventions. We have previ... Read more »
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LowCell ChIP kit IPure kit
The Genomic Basis of Color Pattern Polymorphism in the Harlequin La...
Published: October, 2018
Abstract: Many animal species comprise discrete phenotypic forms. A common example in natural populations of insects is the occurrence of different color pat... Read more »
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Megaruptor
Centromeres License the Mitotic Condensation of Yeast Chromosome Arms.
Published: October, 2018
Abstract: During mitosis, chromatin condensation shapes chromosomes as separate, rigid, and compact sister chromatids to facilitate their segregation. Here, ... Read more »
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Antibody
Caenorhabditis elegans sperm carry a histone-based epigenetic memor...
Published: October, 2018
Abstract: Paternal contributions to epigenetic inheritance are not well understood. Paternal contributions via marked nucleosomes are particularly understudi... Read more »
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IP-Star Compact Microplex Library Preparation kit
Oxidative stress in sperm affects the epigenetic reprogramming in e...
Published: October, 2018
Abstract: BACKGROUND: Reactive oxygen species (ROS)-induced oxidative stress is well known to play a major role in male infertility. Sperm are sensitive to R... Read more »
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Antibody
Long-read sequence capture of the hemoglobin gene clusters across g...
Published: October, 2018
Abstract: Combining high-throughput sequencing with targeted sequence capture has become an attractive tool to study specific genomic regions of interest. Mo... Read more »
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Megaruptor
Promoter bivalency favors an open chromatin architecture in embryon...
Published: October, 2018
Abstract: In embryonic stem cells (ESCs), developmental gene promoters are characterized by their bivalent chromatin state, with simultaneous modification by... Read more »
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Antibody
Macrophage-specific MHCII expression is regulated by a remote enha...
Published: October, 2018
Abstract: MHCII in antigen-presenting cells (APCs) is a key regulator of adaptive immune responses. Expression of MHCII genes is controlled by the transcript... Read more »
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Beads
PWWP2A binds distinct chromatin moieties and interacts with an MTA1...
Published: October, 2018
Abstract: Chromatin structure and function is regulated by reader proteins recognizing histone modifications and/or histone variants. We recently identified ... Read more »
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Antibody Microplex Library Preparation kit
SOX4 can redirect TGF-β-mediated SMAD3-transcriptional output in a ...
Published: October, 2018
Abstract: Expression of the transcription factor SOX4 is often elevated in human cancers, where it generally correlates with tumor-progression and poor-disea... Read more »
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Antibody
Convergent evolution of complex genomic rearrangements in two funga...
Published: October, 2018
Abstract: Meiotic drive is widespread in nature. The conflict it generates is expected to be an important motor for evolutionary change and innovation. In th... Read more »
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IPure kit Microplex Library Preparation kit

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