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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

p27 regulates alpha-synuclein expression.
Published: March, 2018
Abstract: Alpha-synuclein (α-SYN) is the main component of anomalous protein aggregates (Lewy bodies) that play a crucial role in several neurodegenera... Read more »
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IPure kit
Phylogenomic evidence for a recent and rapid radiation of lizards i...
Published: March, 2018
Abstract: Rapid evolutionary radiations are difficult to resolve because divergence events are nearly synchronous and gene flow among nascent species can be ... Read more »
Application of next-generation sequencing to characterize novel mut...
Published: March, 2018
Abstract: Clarithromycin (CLR) resistance has become a predominant factor for treatment failure of H. pylori eradication. Although the molecular me... Read more »
Effects of developmental lead exposure on the hippocampal methylome...
Published: March, 2018
Abstract: Developmental lead (Pb) exposure results in persistent cognitive/behavioral impairments as well as an elevated risk for developing a variety of dis... Read more »
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IP-Star Compact
Histone Deacetylases 1 and 2 Regulate Microglia Function during Dev...
Published: March, 2018
Abstract: Microglia as tissue macrophages contribute to the defense and maintenance of central nervous system (CNS) homeostasis. Little is known about the ep... Read more »
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True MicroChIP kit
EWS-FLI1 increases transcription to cause R-loops and block BRCA1 r...
Published: March, 2018
Abstract: Ewing sarcoma is an aggressive paediatric cancer of the bone and soft tissue. It results from a chromosomal translocation, predominantly t(11;22)(q... Read more »
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Microplex Library Preparation kit
Analysis of Meiotic Double-Strand Break Initiation in Mammals
Published: March, 2018
Abstract: The repair of programmed DNA double-strand breaks (DSBs) physically tethers homologous chromosomes in meiosis t... Read more »
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Bioruptor
A Specific PfEMP1 Is Expressed in P. falciparum Sporozoites and Pla...
Published: March, 2018
Abstract: Heterochromatin plays a central role in the process of immune evasion, pathogenesis, and transmission of the malaria parasite Plasmodium falciparum... Read more »
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Antibody Microplex Library Preparation kit
Corticosteroid receptors adopt distinct cyclical transcriptional si...
Published: March, 2018
Abstract: Mineralocorticoid receptors (MRs) and glucocorticoid receptors (GRs) are two closely related hormone-activated transcription factors that regulate ... Read more »
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ChIP-seq
Corticosteroid receptors adopt distinct cyclical transcriptional si...
Published: March, 2018
Abstract: Mineralocorticoid receptors (MRs) and glucocorticoid receptors (GRs) are two closely related hormone-activated transcription factors that regulate ... Read more »
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ChIP-seq
zHSF1 modulates zper2 expression in zebrafish embryos
Published: March, 2018
Abstract: HSF1 is a transcription factor that plays a key role in circadian resetting by temperature. We have used zebrafish embryos to decipher the roles of... Read more »
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CRISPR
CRL7SMU1 E3 ligase complex driven H2B ubiquitination functions in s...
Published: March, 2018
Abstract: Cullin–RING E3 ligases (CRLs) control broad range of biological processes by ubiquitinating numerous cellular substrates. However, role of CR... Read more »
Differential α-synuclein expression contributes to selective vulner...
Published: March, 2018
Abstract: The accumulation of misfolded α-synuclein (aSyn) and neuron loss define several neurodegenerative disorders including Parkinson’s disea... Read more »
Lyar-mediated recruitment of Brd2 to the chromatin attenuates Nanog...
Published: March, 2018
Abstract: During development, cellular differentiation programs need of tight regulation for proper display of the activity of multiple factors in time and s... Read more »
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Bioruptor
Epigenetic modifiers promote mitochondrial biogenesis and oxidative...
Published: March, 2018
Abstract: During neural development, epigenetic modulation of chromatin acetylation is part of a dynamic, sequential and critical process to steer the fate o... Read more »
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Antibody iDeal ChIP-seq Kit for Histones
Epigenome analysis links gene regulatory elements in group 2 innate...
Published: March, 2018
Abstract: BACKGROUND: Group 2 innate lymphoid cells (ILC2s) are major producers of the cytokines driving allergic asthma, and increased ILC2 numbers have bee... Read more »
Copper induces expression and methylation changes of early developm...
Published: March, 2018
Abstract: Copper contamination is widespread along coastal areas and exerts adverse effects on marine organisms such as mollusks. In the Pacific oyster, copp... Read more »
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MagMeDIP kit Antibody
Genome-wide analysis of PDX1 target genes in human pancreatic proge...
Published: March, 2018
Abstract: OBJECTIVE: Homozygous loss-of-function mutations in the gene coding for the homeobox transcription factor (TF) PDX1 leads to pancreatic agenesis, w... Read more »
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Antibody Microplex Library Preparation kit
Selenite and methylseleninic acid epigenetically affects distinct g...
Published: March, 2018
Abstract: Selenium compounds have emerged as promising chemotherapeutic agents with proposed epigenetic effects, however the mechanisms and downstream effect... Read more »
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iDeal ChIP-seq Kit for Histones
The Transcriptionally Permissive Chromatin State of Embryonic Stem ...
Published: March, 2018
Abstract: A permissive chromatin environment coupled to hypertranscription drives the rapid proliferation of embryonic stem cells (ESCs) and peri-implantatio... Read more »
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LowCell ChIP kit
PRDM9 Methyltransferase Activity Is Essential for Meiotic DNA Doubl...
Published: March, 2018
Abstract: The programmed formation of hundreds of DNA double-strand breaks (DSBs) is essential for proper meiosis and fertility. In mice and humans, the loca... Read more »
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Antibody
Long noncoding RNA LISPR1 is required for S1P signaling and endothe...
Published: March, 2018
Abstract: Sphingosine-1-Phosphate (S1P) is a potent signaling lipid. The effects of S1P are mediated by the five S1P receptors (S1PR). In the endothelium S1P... Read more »
The transcription factors Runx3 and ThPOK cross-regulate acquisitio...
Published: February, 2018
Abstract: Cytotoxic CD4 (CD4CTX) T cells are emerging as an important component of antiviral and antitumor immunity, but the molecular basis of their develop... Read more »
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H3pan (C15310135)
β1-integrin impacts Rad51 stability and DNA double-strand break rep...
Published: February, 2018
Abstract: The molecular mechanisms underlying resistance to radiotherapy in breast cancer cells remain elusive. Previously, we reported that elevated &beta... Read more »
The transcription factors Runx3 and ThPOK cross-regulate acquisitio...
Published: February, 2018
Abstract: Cytotoxic CD4 (CD4) T cells are emerging as an important component of antiviral and antitumor immunity, but the molecular basis of their developmen... Read more »
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Antibody
The CUE1 domain of the SNF2-like chromatin remodeler SMARCAD1 media...
Published: February, 2018
Abstract: Chromatin in embryonic stem cells (ESCs) differs markedly from that in somatic cells, with ESCs exhibiting a more open chromatin configuration. Acc... Read more »
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Antibody
Development of Real-time PCR Assays for the Detection of the pin II...
Published: February, 2018
Abstract: G-rich DNA sequences can form four-stranded G-quadruplex (G4) secondary structures and are linked to fundamental biological processes such as trans... Read more »
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Master Mix
TGFβ signaling hyperactivation-induced tumorigenicity during the de...
Published: February, 2018
Abstract: Clinical therapies of pluripotent stem cells (PSCs)-based transplantation have been hindered by frequent development of teratomas or tumors in anim... Read more »
Aberrant methylated key genes of methyl group metabolism within the...
Published: February, 2018
Abstract: Urothelial carcinoma (UC), the most common cancer of the urinary bladder causes severe morbidity and mortality, e.g. about 40.000 deaths in the EU ... Read more »
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MagMeDIP kit Antibody
A Non-catalytic Function of SETD1A Regulates Cyclin K and the DNA D...
Published: February, 2018
Abstract: MLL/SET methyltransferases catalyze methylation of histone 3 lysine 4 and play critical roles in development and cancer. We assessed MLL/SET protei... Read more »
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Antibody

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