Species-specific regulation of XIST by the JPX/FTX orthologs. Published: February, 2023 Abstract:
X chromosome inactivation (XCI) is an essential process, yet it initiates with remarkable diversity in various mammalian species. XIST, the main trigger of XCI, is controlled in the mouse by an interplay of lncRNA genes (LRGs), some of which evolv... Read more » Tags Antibody
Bridging biological cfDNA features and machine learning approaches. Published: February, 2023 Abstract:
Liquid biopsies (LBs), particularly using circulating tumor DNA (ctDNA), are expected to revolutionize precision oncology and blood-based cancer screening. Recent technological improvements, in combination with the ever-growing understanding of ce... Read more » Tags MagMeDIP kitAntibody
Quantifying propagation of DNA methylation and hydroxymethylation withiDEMS. Published: January, 2023 Abstract:
DNA methylation is a critical epigenetic mark in mammalian cells. Many aspects of DNA methylation maintenance have been characterized; however, the exact kinetics of post-replicative methylation maintenance remain a subject of debate. Here we deve... Read more » Tags Antibody
Consistent DNA Hypomethylations in Prostate Cancer. Published: December, 2022 Abstract:
With approximately 1.4 million men annually diagnosed with prostate cancer (PCa) worldwide, PCa remains a dreaded threat to life and source of devastating morbidity. In recent decades, a significant decrease in age-specific PCa mortality has been ... Read more » Tags MagMeDIP kitAntibody
