Diagenode

Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Intranuclear distribution and local dynamics of RNA polymerase II d...
Published: December, 2007

Abstract: Transcription activation causes dramatic changes in a gene's compaction and macromolecular associations and, in some cases, triggers the translocat... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Interplay of chromatin modifiers on a short basic patch of histone ...
Published: December, 2007

Abstract: Dot1 (Disruptor of telomeric silencing-1) is a histone H3 lysine 79 methyltransferase that contributes to the establishment of heterochromatin boun... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Differential regulation of NAB corepressor genes in Schwann cells.
Published: December, 2007

Abstract: BACKGROUND: Myelination of peripheral nerves by Schwann cells requires not only the Egr2/Krox-20 transactivator, but also the NGFI-A/Egr-binding (N... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
CHD8 associates with human Staf and contributes to efficient U6 RNA...
Published: December, 2007

Abstract: Chromatin remodeling and histone modification are essential for eukaryotic transcription regulation, but little is known about chromatin-modifying ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
The transcription factor snail mediates epithelial to mesenchymal t...
Published: December, 2007

Abstract: The estrogen receptor (ER)-alpha (ESR1) is a key regulatory molecule in mammary epithelial cell development. Loss of ER-alpha in breast cancer is c... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Molecular basis for estrogen receptor alpha deficiency in BRCA1-lin...
Published: November, 2007

Abstract: BACKGROUND: BRCA1-mutant breast tumors are typically estrogen receptor alpha (ER alpha) negative, whereas most sporadic tumors express wild-type BR... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Analysis of transcription, chromatin dynamics and epigenetic change...
Published: November, 2007

Abstract: The ways in which gene transcription is investigated have undergone radical change since the turn of the millennium. Piece-meal approaches focussed... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
The JmjC domain protein Epe1 prevents unregulated assembly and disa...
Published: October, 2007

Abstract: Heterochromatin normally has prescribed chromosomal positions and must not encroach on adjacent regions. We demonstrate that the fission yeast prot... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Heme oxygenase-1 induction by NRF2 requires inactivation of the tra...
Published: October, 2007

Abstract: Oxidative stress activates the transcription factor NRF2, which in turn binds cis-acting antioxidant response element (ARE) enhancers and induces e... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Epigenetic regulation (DNA methylation, histone modifications) of t...
Published: October, 2007

Abstract: The human genes MUC2, MUC5AC, MUC5B and MUC6 are clustered on chromosome 11 and encode large secreted gel-forming mucins. The frequent occurrence o... Read more »

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Antibody
Chromium cross-links histone deacetylase 1-DNA methyltransferase 1 ...
Published: October, 2007

Abstract: Transcriptional regulation of gene expression requires posttranslational modification of histone proteins, which, in concert with chromatin-remodel... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Mallory body formation is associated with epigenetic phenotypic cha...
Published: October, 2007

Abstract: Microarrays were done on the livers of mice fed DDC for 10 weeks, withdrawn 1 month (DDC primed livers) and refed 6 days, and compared with mice fe... Read more »

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Antibody
Protein arginine-methyltransferase-dependent oncogenesis.
Published: October, 2007

Abstract: Enzymes that mediate reversible epigenetic modifications have not only been recognized as key in regulating gene expression and oncogenesis, but al... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Redundancy of chromatin remodeling pathways for the induction of th...
Published: September, 2007

Abstract: Induction of the yeast PHO5 and PHO8 genes leads to a prominent chromatin transition at their promoter regions as a prerequisite for transcription ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Activator-mediated recruitment of the MLL2 methyltransferase comple...
Published: August, 2007

Abstract: MLL-containing complexes methylate histone H3 at lysine 4 (H3K4) and have been implicated in the regulation of transcription. However, it is unclea... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Genome-wide maps of chromatin state in pluripotent and lineage-comm...
Published: August, 2007

Abstract: We report the application of single-molecule-based sequencing technology for high-throughput profiling of histone modifications in mammalian cells.... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
NuA4-directed chromatin transactions throughout the Saccharomyces c...
Published: August, 2007

Abstract: Two of the major histone acetyltransferases in Saccharomyces cerevisiae are NuA4 and SAGA, which acetylate histones H4 and H3, respectively. Acetyl... Read more »

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Bioruptor Chromatin Shearing
MTERF3 is a negative regulator of mammalian mtDNA transcription.
Published: July, 2007

Abstract: Regulation of mammalian mtDNA gene expression is critical for altering oxidative phosphorylation capacity in response to physiological demands and ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
HDAC1 bound to the Cyp1a1 promoter blocks histone acetylation assoc...
Published: July, 2007

Abstract: Metabolic bioactivation of polycyclic aromatic hydrocarbons, such as the environmental procarcinogen benzo[a]pyrene, is catalyzed by a cytochrome P... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
E2F activation of S phase promoters via association with HCF-1 and ...
Published: July, 2007

Abstract: E2F transcriptional regulators control human-cell proliferation by repressing and activating the transcription of genes required for cell-cycle pro... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Plasticity of fission yeast CENP-A chromatin driven by relative lev...
Published: July, 2007

Abstract: The histone H3 variant CENP-A assembles into chromatin exclusively at centromeres. The process of CENP-A chromatin assembly is epigenetically regul... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
RNAi-dependent H3K27 methylation is required for heterochromatin fo...
Published: June, 2007

Abstract: Methylated H3K27 is an important mark for Polycomb group (PcG) protein-mediated transcriptional gene silencing (TGS) in multicellular eukaryotes. H... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Notch activation stimulates transient and selective binding of Su(H...
Published: June, 2007

Abstract: The CSL [CBF1/Su(H)/Lag2] proteins [Su(H) in Drosophila] are implicated in repression and activation of Notch target loci. Prevailing models imply ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
CHD4/Mi-2beta activity is required for the positioning of the mesod...
Published: April, 2007

Abstract: Experiments in Xenopus have illustrated the importance of extracellular morphogens for embryonic gene regulation in vertebrates. Much less is known... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Ubiquitylation of histone H2B controls RNA polymerase II transcript...
Published: April, 2007

Abstract: Transcription by RNA polymerase II (polII) is accompanied by dramatic changes in chromatin structure. Numerous enzymatic activities contribute to t... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Carbon nanotube polymer composites for photonic devices
Published: March, 2007

Abstract: We report the fabrication of high optical quality single wall carbon nanotube polyvinyl alcohol composites and their application in nanotube based ... Read more »

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Bioruptor
Identification of novel functional TBP-binding sites and general fa...
Published: February, 2007

Abstract: Our current knowledge of the general factor requirement in transcription by the three mammalian RNA polymerases is based on a small number of model... Read more »

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Antibody
An unmethylated 3' promoter-proximal region is required for efficie...
Published: February, 2007

Abstract: The promoter regions of approximately 40% of genes in the human genome are embedded in CpG islands, CpG-rich regions that frequently extend on the ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Genetic unmasking of an epigenetically silenced microRNA in human c...
Published: February, 2007

Abstract: The mechanisms underlying microRNA (miRNA) disruption in human disease are poorly understood. In cancer cells, the transcriptional silencing of tum... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Modulation of drug-stimulated ATPase activity of human MDR1/P-glyco...
Published: January, 2007

Abstract: MDR1 (multidrug resistance 1)/P-glycoprotein is an ATP-driven transporter which excretes a wide variety of structurally unrelated hydrophobic compo... Read more »

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Liposome Preparation

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