Diagenode

Workflow for FFPE-derived DNA shearing prior to Next Generation Sequencing

Formalin fixation and paraffin embedding (FFPE) is a standard method for long-term preservation of most archived pathological specimens. Archival FFPE samples provide an invaluable repository of information for genetic analysis. These samples can be analyzed by next-generation sequencing for applications including biomarker discovery, drug development, and cancer research. However, DNA from archival tissues is challenging to use in NGS studies due to insufficient quality, including degradation, chemical modifications and the presence of single-stranded molecules.

Events

  • 20th Annual Biomarkers & Precision Medicine Congress
    London, UK
    Sep 30-Oct 1, 2025
 See all events

 


       Site map   |   Contact us   |   Conditions of sales   |   Conditions of purchase   |   Privacy policy