Diagenode

Workflow for FFPE-derived DNA shearing prior to Next Generation Sequencing

Formalin fixation and paraffin embedding (FFPE) is a standard method for long-term preservation of most archived pathological specimens. Archival FFPE samples provide an invaluable repository of information for genetic analysis. These samples can be analyzed by next-generation sequencing for applications including biomarker discovery, drug development, and cancer research. However, DNA from archival tissues is challenging to use in NGS studies due to insufficient quality, including degradation, chemical modifications and the presence of single-stranded molecules.

イベント

  • Genome instability: when RNA meets chromatin
    Roscoff
    Sep 16-Jun 20, 2019
  • Japanese Biochemical Society
    Yokohama
    Sep 18-Sep 20, 2019
  • The 2019 PacBio Long-Read Revolution: Highly Accurate and Affordable SMRT Sequencing
    Atlanta, Georgia
    Sep 19, 2019
  • The 2019 PacBio Long-Read Revolution: Highly Accurate and Affordable SMRT Sequencing
    RTP, North Carolina
    Sep 20, 2019
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