Diagenode

Datasheet MethylCap Protein

This MethylCap protein has been extensively validated for specific isolation of DNA containing methylated CpGs. It consists of the methyl binding domain (MBD) of human MeCP2, as a C-terminal fusion with Glutathione-S-transferase (GST) containing an N-terminal His6-tag. A single fully methylated CpG is sufficient for the interaction between the MethylCap protein and methylated DNA

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