Diagenode

Shearing Technologies

Diagenode focuses on state-of-the-art preparation of high quality biological samples and is dedicated to the most advanced analytical methods. Achieving proper fragment sizes for input DNA, chromatin, or RNA is crucial for various techniques, and Diagenode has developed the most advanced water bath sonicators (the Bioruptor® for 150bp - 2kb), a unique desktop sonication device (the One® for 150bp - 1kb) and a unique hydrodynamic shearing instrument (the Megaruptor® for 2kb - 75kb) to cover a range of applications. The Bioruptor® is available in two models: the Bioruptor® Plus, specifically designed for ChIP-PCR and other applications, and the Bioruptor® Pico for ChIP-seq and NGS. The Megaruptor® is the best shearing device for the tightest distribution of long DNA fragments. The One® is the new desktop solution that provides optimal small volume DNA shearing for Next-Generation-Sequencing.

Bioruptor®

Megaruptor®

One®

Features

  • All in one shearing device
  • Advanced temperature control
  • > 2000 peer reviewed publications
  • Optimal for long DNA fragment generation
  • Thight fragment length distribution
  • Hydropores eliminate clogging issue
  • Compact size
  • Small volume DNA shearing
  • Fully integrated system

Applications

  • DNA, Chromatin and RNA shearing 150bp to 2kb
  • FFPE DNA and RNA extraction
  • Protein extraction from cells and tissues
  • Chemical applications (liposomes, emulsifications etc.)
  • DNA shearing 2kb to 75kb
  • DNA shearing 150bp to 1kb

  • Bioruptor®


    • Bioruptor-pico-next-gen-sequencing
      B01060001
      Bioruptor® Pico sonication device
    • some alt
      B01020001
      Bioruptor® Plus sonication device
  • Megaruptor®


    • megaruptor
      B06010001
      Megaruptor®
  • One®


    • Bioruptor One
      B01070001
      Diagenode One sonication device

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