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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

To remove Quantitative comparison of genome-wide DNA methylation ma...
Published: October, 2010
Abstract: DNA methylation plays a key role in regulating eukaryotic gene expression. Although mitotically heritable and stable over time, patterns of DNA met... Read more »
DNA methylation and Yin Yang-1 repress adenosine A2A receptor level...
Published: October, 2010
Abstract: Adenosine A(2A) receptors (A(2A) Rs) are G-protein coupled receptors that stimulate adenylyl cyclase activity. The most A(2A) Rs-enriched brain reg... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR LowCell ChIP kit
A chromatin-remodeling protein is a component of fission yeast medi...
Published: September, 2010
Abstract: The multiprotein Mediator complex is an important regulator of RNA polymerase II-dependent genes in eukaryotic cells. In contrast to the situation ... Read more »
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Bioruptor Chromatin Shearing
Distinct epigenetic domains separated by a CTCF bound insulator bet...
Published: September, 2010
Abstract: BACKGROUND: Tumor suppressor gene (TSG) RASSF1A and candidate TSG BLU are two tandem head-to-tail genes located at 3p21.3. We hypothesized that the... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
HAATI survivors replace canonical telomeres with blocks of generic ...
Published: September, 2010
Abstract: The notion that telomeres are essential for chromosome linearity stems from the existence of two chief dangers: inappropriate DNA damage response (... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
SATB1 dictates expression of multiple genes including IL-5 involved...
Published: September, 2010
Abstract: Special AT-rich binding protein 1 (SATB1) is a global chromatin organizer and a transcription factor regulated by interleukin-4 (IL-4) during the e... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Chromatin remodeling is required for gene reactivation after decita...
Published: September, 2010
Abstract: The DNA hypomethylating drug decitabine (DAC) reactivates silenced gene expression in cancer and is approved for the treatment of the myelodysplast... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Transcriptional profiling of day 12 porcine embryonic disc and trop...
Published: September, 2010
Abstract: cDNA derived from trophectoderm (TE) and embryonic disc (ED) of a single day 12 porcine embryo was subjected to next-generation sequencing using th... Read more »
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DNA shearing Bioruptor
Demonstrating polymorphic miRNA-mediated gene regulation in vivo: a...
Published: September, 2010
Abstract: We herein describe the development of a biochemical method to evaluate the effect of single nucleotide polymorphisms (SNPs) in target genes on thei... Read more »
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Bioruptor Cell Lysis Enzymatic Assay
Cellular and pharmacological selectivity of the peroxisome prolifer...
Published: September, 2010
Abstract: The availability of high-affinity agonists for peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) has led to significant advanc... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Induction of pluripotency in human cord blood unrestricted somatic ...
Published: September, 2010
Abstract: OBJECTIVE: Generation of induced pluripotent stem (iPS) cells from human cord blood (CB)-derived unrestricted somatic stem cells and evaluation of ... Read more »
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MeDIP kit
Methylation profiling in individuals with uniparental disomy identi...
Published: September, 2010
Abstract: The maternal and paternal genomes possess distinct epigenetic marks that distinguish them at imprinted loci. In order to identify imprinted loci, w... Read more »
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Antibody
The histone H3K36 methyltransferase MES-4 acts epigenetically to tr...
Published: September, 2010
Abstract: Methylation of histone H3K36 in higher eukaryotes is mediated by multiple methyltransferases. Set2-related H3K36 methyltransferases are targeted to... Read more »
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Chromatin Shearing ChIP-qPCR
DNA methylation prevents CTCF-mediated silencing of the oncogene BC...
Published: August, 2010
Abstract: Aberrant DNA methylation commonly occurs in cancer cells where it has been implicated in the epigenetic silencing of tumor suppressor genes. Additi... Read more »
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DNA shearing Bioruptor Chromatin Shearing ChIP-qPCR
Iron regulatory proteins secure mitochondrial iron sufficiency and ...
Published: August, 2010
Abstract: Mitochondria supply cells with ATP, heme, and iron sulfur clusters (ISC), and mitochondrial energy metabolism involves both heme- and ISC-dependent... Read more »
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Bioruptor Cell Lysis
The distribution of active RNA polymerase II along the transcribed ...
Published: August, 2010
Abstract: In order to study the intragenic profiles of active transcription, we determined the relative levels of active RNA polymerase II present at the 3'-... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Genome-wide mapping of histone H4 serine-1 phosphorylation during s...
Published: August, 2010
Abstract: We previously showed that histone H4 serine-1 phosphorylation (H4S1ph) is evolutionarily conserved during gametogenesis, and contributes to post-me... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Genome-wide profiling of p63 DNA-binding sites identifies an elemen...
Published: August, 2010
Abstract: Heterozygous mutations in p63 are associated with split hand/foot malformations (SHFM), orofacial clefting, and ectodermal abnormalities. Elucidati... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
The repressing function of the oncoprotein BCL-3 requires CtBP, whi...
Published: August, 2010
Abstract: The nuclear and oncogenic BCL-3 protein activates or represses gene transcription when bound to NF-kappaB proteins p50 and p52, yet the molecules t... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Ring1B and Suv39h1 delineate distinct chromatin states at bivalent ...
Published: August, 2010
Abstract: Pluripotent cells develop within the inner cell mass of blastocysts, a mosaic of cells surrounded by an extra-embryonic layer, the trophectoderm. W... Read more »
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Antibody
Differential regulation of HIC1 target genes by CtBP and NuRD, via ...
Published: August, 2010
Abstract: The tumor suppressor gene HIC1 encodes a transcriptional repressor involved in regulatory loops modulating P53-dependent and E2F1-dependent cell su... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
miR-192 mediates TGF-beta/Smad3-driven renal fibrosis.
Published: August, 2010
Abstract: TGF-beta/Smad3 promotes renal fibrosis, but the mechanisms that regulate profibrotic genes remain unclear. We hypothesized that miR-192, a microRNA... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
The down-regulation of the human MYC gene by the nuclear hormone 1a...
Published: July, 2010
Abstract: MYC is a pleiotropic transcription factor that coordinates the expression of diverse programs that are together necessary for the growth and expans... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Terminal osseous dysplasia is caused by a single recurrent mutation...
Published: July, 2010
Abstract: Terminal osseous dysplasia (TOD) is an X-linked dominant male-lethal disease characterized by skeletal dysplasia of the limbs, pigmentary defects o... Read more »
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DNA shearing Bioruptor
Conserved role of intragenic DNA methylation in regulating alternat...
Published: July, 2010
Abstract: Although it is known that the methylation of DNA in 5' promoters suppresses gene expression, the role of DNA methylation in gene bodies is unclear.... Read more »
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DNA shearing Bioruptor
The NoRC complex mediates the heterochromatin formation and stabili...
Published: July, 2010
Abstract: Maintenance of specific heterochromatic domains is crucial for genome stability. In eukaryotic cells, a fraction of the tandem-repeated ribosomal R... Read more »
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Antibody Master Mix
Novel trans-tail regulation of H2B ubiquitylation and H3K4 methylat...
Published: July, 2010
Abstract: Chromatin is regulated by cross talk among different histone modifications, which can occur between residues within the same tail or different tail... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Loss of Rb proteins causes genomic instability in the absence of mi...
Published: July, 2010
Abstract: Loss of G1/S control is a hallmark of cancer, and is often caused by inactivation of the retinoblastoma pathway. However, mouse embryonic fibroblas... Read more »
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DNA shearing Bioruptor
Aryl hydrocarbon receptor and NF-E2-related factor 2 are key regula...
Published: July, 2010
Abstract: Multidrug resistance protein 4 (MRP4; ABCC4) is an ATP binding cassette transporter that facilitates the excretion of bile salt conjugates and othe... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
The impact of intragenic CpG content on gene expression.
Published: July, 2010
Abstract: The development of vaccine components or recombinant therapeutics critically depends on sustained expression of the corresponding transgene. This s... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR

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  • 14th International Symposium on Minimal Residual Cancer
    Nice, France
    May 7-May 9, 2025
  • 23rd BioPharma Drug Discovery Nexus
    San Francisco
    May 7-May 8, 2025
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