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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Tandem ChoRE and CCAAT motifs and associated factors regulate Txnip...
Published: January, 2009
Abstract: BACKGROUND: Thioredoxin interacting protein (Txnip) is a multifunctional protein involved in regulation of cell cycle events and cellular metabolis... Read more »
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Antibody
TBP2 is a substitute for TBP in Xenopus oocyte transcription.
Published: January, 2009
Abstract: BACKGROUND: TATA-box-binding protein 2 (TBP2/TRF3) is a vertebrate-specific paralog of TBP that shares with TBP a highly conserved carboxy-terminal... Read more »
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Antibody
The chromodomain of LIKE HETEROCHROMATIN PROTEIN 1 is essential for...
Published: January, 2009
Abstract: Polycomb group (PcG) proteins are essential to maintain gene expression patterns during development. Transcriptional repression by PcG proteins inv... Read more »
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Antibody LowCell ChIP kit
TIPT2 and geminin interact with basal transcription factors to syne...
Published: January, 2009
Abstract: BACKGROUND: The re-replication inhibitor Geminin binds to several transcription factors including homeodomain proteins, and to members of the polyc... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Antibody
Epigenetic engineering of ribosomal RNA genes enhances protein prod...
Published: January, 2009
Abstract: Selection of mammalian high-producer cell lines remains a major challenge for the biopharmaceutical manufacturing industry. Ribosomal RNA (rRNA) ge... Read more »
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Antibody Master Mix
Methylated DNA immunoprecipitation and microarray-based analysis: d...
Published: January, 2009
Abstract: The methylated DNA immunoprecipitation microarray (MeDIP-chip) is a genome-wide, high-resolution approach to detect DNA methylation in whole genome... Read more »
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DNA shearing Bioruptor Antibody
The ASH1 HOMOLOG 2 (ASHH2) histone H3 methyltransferase is required...
Published: January, 2009
Abstract: BACKGROUND: SET-domain proteins are histone lysine (K) methyltransferases (HMTase) implicated in defining transcriptionally permissive or repressiv... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Approaches to determine expression of inflammatory cytokines.
Published: January, 2009
Abstract: There is an increasing awareness of the role of inflammation in cancer. Immune responses can limit the growth of some tumors, but paradoxically, ma... Read more »
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Bioruptor Tissue Homogenization
Cooperation between NRF-2 and YY-1 transcription factors is essenti...
Published: January, 2009
Abstract: BACKGROUND: Many mammalian genes are organized as bidirectional (head-to-head) gene pairs with the two genes separated only by less than 1 kb. The ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Core promoter acetylation is not required for high transcription fr...
Published: January, 2009
Abstract: BACKGROUND: Acetylation of promoter nucleosomes is tightly correlated and mechanistically linked to gene activity. However, transcription is not ne... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Remodeling of the chromatin structure of the facioscapulohumeral mu...
Published: January, 2009
Abstract: BACKGROUND: Facioscapulohumeral muscular dystrophy (FSHD) is an autosomal dominant neuromuscular disorder associated with the partial deletion of i... Read more »
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Antibody
Improving the efficiency of genomic loci capture using oligonucleot...
Published: January, 2009
Abstract: BACKGROUND: The emergence of next-generation sequencing technology presents tremendous opportunities to accelerate the discovery of rare variants o... Read more »
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DNA shearing Bioruptor
Monodispersity of recombinant Cre recombinase correlates with its e...
Published: January, 2009
Abstract: BACKGROUND: Cre recombinase is a common reagent used for the in vivo on/off switching of the expression of target genes flanked by loxP sites. In p... Read more »
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Bioruptor Cell Lysis
Multiple histone modifications in euchromatin promote heterochromat...
Published: January, 2009
Abstract: BACKGROUND: Methylation of lysine 79 on histone H3 by Dot1 is required for maintenance of heterochromatin structure in yeast and humans. However, t... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Sox17 promotes cell cycle progression and inhibits TGF-beta/Smad3 s...
Published: January, 2009
Abstract: The Sry-related high mobility group box transcription factor Sox17 is required for diverse developmental processes including endoderm formation, va... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
The protein tyrosine phosphatase receptor type R gene is an early a...
Published: January, 2009
Abstract: BACKGROUND: Tumor development in the human colon is commonly accompanied by epigenetic changes, such as DNA methylation and chromatin modifications... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Identification of the core element responsive to runt-related trans...
Published: January, 2009
Abstract: OBJECTIVE: Type X collagen and runt-related transcription factor 2 (RUNX-2) are known to be important for chondrocyte hypertrophy during skeletal g... Read more »
BEAF regulates cell-cycle genes through the controlled deposition o...
Published: December, 2008
Abstract: Chromatin insulators/boundary elements share the ability to insulate a transgene from its chromosomal context by blocking promiscuous enhancer-prom... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
p53-Responsive micrornas 192 and 215 are capable of inducing cell c...
Published: December, 2008
Abstract: microRNAs provide a novel layer of regulation for gene expression by interfering with the stability and/or translation of specific target mRNAs. Ov... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Myc regulates a transcriptional program that stimulates mitochondri...
Published: December, 2008
Abstract: Mammalian cells fuel their growth and proliferation through the catabolism of two main substrates: glucose and glutamine. Most of the remaining met... Read more »
Optimization of experimental design parameters for high-throughput ...
Published: December, 2008
Abstract: High-throughput, microarray-based chromatin immunoprecipitation (ChIP-chip) technology allows in vivo elucidation of transcriptional networks. Howe... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
NF-Y substitutes H2A-H2B on active cell-cycle promoters: recruitmen...
Published: November, 2008
Abstract: The CCAAT box is a frequent promoter element, as illustrated by bioinformatic analysis, and it is bound by NF-Y, a trimer with H2A-H2B-like subunit... Read more »
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Antibody
Transcriptional regulation of IRS5/DOK4 expression in non-small-cel...
Published: November, 2008
Abstract: The insulin-receptor substrate family plays important roles in cellular growth, signaling, and survival. Two new members of this family have recent... Read more »
Multi-walled carbon nanotubes injure the plasma membrane of macroph...
Published: October, 2008
Abstract: Carbon nanotubes (CNTs) are emerging nanotechnology materials which are likely to be mass-produced in the near future. However, prior to mass-produ... Read more »
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Cell Lysis Western Blot
The LPS-induced transcriptional upregulation of the chicken lysozym...
Published: October, 2008
Abstract: Transcription of the lysozyme gene is rapidly induced by proinflammatory stimuli such as treatment with bacterial lipopolysaccharide (LPS). Here we... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Pax5 and linker histone H1 coordinate DNA methylation and histone m...
Published: October, 2008
Abstract: The 3' regulatory region (3' RR) of the murine immunoglobulin heavy chain (IgH) locus contains multiple DNase I-hypersensitive (hs) sites. Proximal... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Genomewide analysis of PRC1 and PRC2 occupancy identifies two class...
Published: October, 2008
Abstract: In embryonic stem (ES) cells, bivalent chromatin domains with overlapping repressive (H3 lysine 27 tri-methylation) and activating (H3 lysine 4 tri... Read more »
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Chromatin Shearing ChIP-qPCR
Novel isoenzyme of 2-oxoglutarate dehydrogenase is identified in br...
Published: October, 2008
Abstract: 2-Oxoglutarate dehydrogenase (OGDH) is the first and rate-limiting component of the multienzyme OGDH complex (OGDHC) whose malfunction is associate... Read more »
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Bioruptor Mitochondria disruption
Genome-associated RNA polymerase II includes the dissociable Rpb4/7...
Published: September, 2008
Abstract: Yeast RNA polymerase (Pol) II consists of a 10-subunit core enzyme and the Rpb4/7 subcomplex, which is dispensable for catalytic activity and disso... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Postmitotic Nkx2-1 controls the migration of telencephalic interneu...
Published: September, 2008
Abstract: The homeodomain transcription factor Nkx2-1 plays key roles in the developing telencephalon, where it regulates the identity of progenitor cells in... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR

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