Dietary methionine starvation impairs acute myeloid leukemia progression. Published: November, 2022 Abstract:
Targeting altered tumor cell metabolism might provide an attractive opportunity for patients with acute myeloid leukemia (AML). An amino acid dropout screen on primary leukemic stem cells and progenitor populations revealed a number of amino acid ... Read more » Tags Antibody
The telomeric protein TERF2/TRF2 impairs HMGB1-driven autophagy. Published: October, 2022 Abstract:
TERF2/TRF2 is a pleiotropic telomeric protein that plays a crucial role in tumor formation and progression through several telomere-dependent and -independent mechanisms. Here, we uncovered a novel function for this protein in regulating the macro... Read more » Tags Antibody
The genome sequence of the satellite, Eupsilia transversa (Hufnagel,1766) Published: October, 2022 Abstract:
We present a genome assembly from an individual female Eupsilia transversa (the satellite; Arthropoda; Insecta; Lepidoptera; Noctuidae). The genome sequence is 467 megabases in span. The entire assembly (100\%) is scaffolded into 32 chromosomal ps... Read more » Tags Antibody
Distinct silencer states generate epigenetic states of heterochromatin. Published: August, 2022 Abstract:
Heterochromatic loci can exhibit different transcriptional states in genetically identical cells. A popular model posits that the inheritance of modified histones is sufficient for inheritance of the silenced state. However, silencing inheritance ... Read more » Tags Antibody
