The RNA m5C Methylase NSUN2 Modulates Corneal EpithelialWound Healing. Published: March, 2023 Abstract:
PURPOSE: The emerging epitranscriptomics offers insights into the physiopathological roles of various RNA modifications. The RNA methylase NOP2/Sun domain family member 2 (NSUN2) catalyzes 5-methylcytosine (m5C) modification of mRNAs. However, the... Read more » Tags Antibody
Species-specific regulation of XIST by the JPX/FTX orthologs. Published: February, 2023 Abstract:
X chromosome inactivation (XCI) is an essential process, yet it initiates with remarkable diversity in various mammalian species. XIST, the main trigger of XCI, is controlled in the mouse by an interplay of lncRNA genes (LRGs), some of which evolv... Read more » Tags Antibody
Bridging biological cfDNA features and machine learning approaches. Published: February, 2023 Abstract:
Liquid biopsies (LBs), particularly using circulating tumor DNA (ctDNA), are expected to revolutionize precision oncology and blood-based cancer screening. Recent technological improvements, in combination with the ever-growing understanding of ce... Read more » Tags MagMeDIP kitAntibody
Quantifying propagation of DNA methylation and hydroxymethylation withiDEMS. Published: January, 2023 Abstract:
DNA methylation is a critical epigenetic mark in mammalian cells. Many aspects of DNA methylation maintenance have been characterized; however, the exact kinetics of post-replicative methylation maintenance remain a subject of debate. Here we deve... Read more » Tags Antibody
