Diagenode

DNA Methylation Profiling (RRBS Service)

2 publications found.

Paternal sepsis induces alterations of the sperm methylome and dampens offspring immune responses—an animal study
Published: June, 2018

Abstract: Abstract Background Sepsis represents the utmost severe consequence of infection, involving a dysregulated and self-damaging immune response of the host. While different environmental exposures like chronic stress or malnutrition have been...
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DNMT3B overexpression contributes to aberrant DNA methylation and MYC-driven tumor maintenance in T-ALL and Burkitt’s lymphoma
Published: August, 2017

Abstract: Aberrant DNA methylation is a hallmark of cancer. However, our understanding of how tumor cell-specific DNA methylation patterns are established and maintained is limited. Here, we report that in T-cell acute lymphoblastic leukemia (T-ALL) and Bur...
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