Diagenode

Diagenode® Premium RRBS technology: cost-effective DNA methylation mapping with superior coverage


Anne-Clémence Veillard, Paul Datlinger, Miklos Laczik, Sharon Squazzo & Christoph Bock

Reduced representation bisulfite sequencing (RRBS) enables genome-scale DNA methylation analysis in any vertebrate species. The assay benefits from the practical advantages of bisulfite sequencing while avoiding the cost of whole-genome sequencing. The Diagenode Premium RRBS kit makes this technology widely available and provides high coverage (up to 4 million CpGs in human samples). Multiplexing prior to bisulfite conversion allows processing of 96 samples per experiment, enabling studies of large cohorts.

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Published
January, 2016

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Products used in this publication

  • Methylation kit icon
    C02030032
    Premium RRBS kit (24 rxns) - replaced by Premiu...
  • Methylation kit icon
    C02030033
    Premium RRBS kit (96 rxns) - replaced by Premiu...
  • default alt
    G02020000
    RRBS Service (Reduced Representation Bisulfite ...
  • default alt
    C02030035
    Bisulfite conversion reagent for RRBS
  • Methylation kit icon
    C02030036
    Premium RRBS kit V2 RRBS for low DNA amounts ...
  • Methylation kit icon
    C02030037
    Premium RRBS kit V2 x96 RRBS for low DNA amoun...

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