Diagenode

Ultrasensitive proteomics for microdissected fresh frozen tissue samples using the Bioruptor® Pico for sample preparation

Histology-defined proteomics investigations are a fundamental tool in modern molecular pathology. Molecular signatures of specific cells must be detected within their correct histopathological context to draw conclusions regarding disease development and progression. The proteomics group at the Fondazione Pisana per la Scienza ONLUS is developing advanced mass spectrometry protocols for proteomics characterization of oncological and neurological samples. This involves mass spectrometry imaging (MSI), for its seamless integration with histopathological analysis, as well as histology/MSI directed laser capture microdissection for in-depth quantitative proteomics 1,2. The LC-MS/MS based proteomics on microdissected samples requires the miniaturization of the traditional bottom-up protocols.

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Events

  • Virtual ChIP workshop - January 18-19, 2022 or January 25-26, 2022
    Diagenode
    Jan 18-Jan 26, 2022
  • Virtual DNA Methylation - January 18-19, 2022 or January 25-26, 2022
    Diagenode
    Jan 18-Jan 26, 2022
  • Lausanne Genomics Days 2022
    Lausanne, Switzerland
    Feb 14-Feb 15, 2022
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News

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The European Regional Development Fund and Wallonia are investing in your future.

Extension of industrial buildings and new laboratories.


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