The protein G-coated magnetic beads have been extensively validated in chromatin immunoprecipitation assay (ChIP). These beads are intended for isolation of immune complexes (chromatin and specific antibody) in ChIP experiments. The beads are suitable for immunoprecipitation of mouse IgG1, IgG2a, IgG2b and IgG3, rat IgG1, IgG2a, IgG2b and IgG3 rabbit and goat polyclonal Abs and human IgG1, IgG2, IgG3 and IgG4. The beads should be washed before use.
Diagenode strongly recommends using this: DiaMag protein G-coated magnetic beads (ChIP-seq grade) (Diagenode Cat# C03010021-220). Click here to copy to clipboard.
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Polycomb repressive complex 2 (PRC2) silences genes responsible for neurodegeneration von Schimmelmann M et al. Normal brain function depends on the interaction between highly specialized neurons that operate within anatomically and functionally distinct brain regions. Neuronal specification is driven by transcriptional programs that are established during early neuronal development and remain in place in the adult brain. The...
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