CUT&Tag Service

CUT&Tag (Cleavage Under Targets & Tagmentation) followed by sequencing is  an advanced chromatin profiling technology that enables precise mapping of protein–DNA interactions with minimal cell input and exceptionally low background. Leveraging our latest innovation, the Universal CUT&Tag Kit, our CUT&Tag Service provides high-resolution chromatin profiling for both histone and non-histone targets, including transcription factors and chromatin-associated proteins. 

This method can be considered an alternative to ChIP-seq, which is the gold standard for chromatin analysis of histone modifications, transcription factors, and chromatin modifiers/remodelers. Unlike ChIP-seq, which requires a high input of materials (millions of cells), CUT&Tag is effective with much lower sample quantities.

The Most Accurate Low-Input Chromatin Profiling

• Higher data quality from low-input samples (compared to ChIP-seq)
• High signal-to-noise ratio, even with challenging marks
• Fast turnaround time (TAT): no optimization needed, quick results delivery
• Compatible with low cell amounts: Requires 10x fewer cells compared to standard ChIP-seq methods
• End-to-end  services: from cells to antibody-targeted tagmentation, library preparation, and sequencing
• A la carte bioinformatic service: from standard analysis to advanced one with comparative and multiomics integration (with RNA or DNA methylation data)