As the role of the changes in the epigenome is becoming more and more revealed there are a growing number of scientific papers reporting epigenetic/epigenomic studies. Malicious epigenomic alterations can be the reason behind widespread social problems like different types of cancers (eg. breast cancer), as well as rare diseases like ICF (Immunodeficiency, Centromeric region instability, Facial anomalies) syndrome, the like of which often not interest the medical industry therefore the diagnostic/therapeutic products are underdeveloped or non-existent at all. Such chromatin diseases (Rett syndrome, ATRX syndrome, FSHD, ICF syndrome) are the subject of the DisChrom project (FP7 project under the grant agreement PTN-GA-2009-238242) in which we participate.
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