Diagenode

Workflow for FFPE-derived DNA shearing prior to Next Generation Sequencing

Formalin fixation and paraffin embedding (FFPE) is a standard method for long-term preservation of most archived pathological specimens. Archival FFPE samples provide an invaluable repository of information for genetic analysis. These samples can be analyzed by next-generation sequencing for applications including biomarker discovery, drug development, and cancer research. However, DNA from archival tissues is challenging to use in NGS studies due to insufficient quality, including degradation, chemical modifications and the presence of single-stranded molecules.

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Events

  • Long-Read Sequencing Meeting 2024
    Uppsala, Sweden
    Oct 21-Oct 23, 2024
  • NextGen Omics 2024
    London, UK
    Oct 23-Oct 25, 2024
  • FEBS 2024
    Budapest, Hungary
    Oct 28-Oct 31, 2024
  • 5th Danube Conference on Epigenetics
    Budapest, Hungary
    Oct 28-Oct 31, 2024
 See all events

 


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