Diagenode

Workflow for FFPE-derived DNA shearing prior to Next Generation Sequencing

Formalin fixation and paraffin embedding (FFPE) is a standard method for long-term preservation of most archived pathological specimens. Archival FFPE samples provide an invaluable repository of information for genetic analysis. These samples can be analyzed by next-generation sequencing for applications including biomarker discovery, drug development, and cancer research. However, DNA from archival tissues is challenging to use in NGS studies due to insufficient quality, including degradation, chemical modifications and the presence of single-stranded molecules.

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Events

  • A Century of Genetics
    Edinburgh
    Nov 13-Nov 15, 2019
  • EMEA User Group Meeting - PacBio
    Barceló Hotel, Milan, Italy
    Nov 14-Nov 15, 2019
 See all events

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