Diagenode

Application of the Bioruptor® Pico for best shearing of yeast genomic DNA for NGS

DNA shearing is important step for next-generation sequencing library preparation. Important is reproducibility and ef ciency of shearing. S. cerevisiae is yeast and have smaller amount of DNA per cells. They have a cell wall so the conditions which we use for the genomic DNA from yeast are different than for mammalian cells.

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