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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

The ETS transcription factor ERF controls the exit from the naïve p...
Published: October, 2021
Abstract: The naïve epiblast transitions to a pluripotent primed state during embryo implantation. Despite the relevance of the FGF pathway during this ... Read more »
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Premium RRBS Kit DNA Methylation
Adaptive Convergence of Methylomes Reveals Epigenetic Driversand Bo...
Published: October, 2021
Abstract: Ependymoma (EPN) is the third most common brain tumor in children and frequently recurs. Here, we report an integrated longitudinal analysis of epi... Read more »
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Premium RRBS Kit
Short-Chain Fatty Acids Calibrate RARα Activity RegulatingFood Sens...
Published: October, 2021
Abstract: Gut-microbiota dysbiosis links to allergic diseases. The mechanism of the exacerbation of food allergy caused by gut-microbiota dysbiosis remains u... Read more »
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Antibody
Autocrine Vitamin D-signaling switches off pro-inflammatory program...
Published: October, 2021
Abstract: The molecular mechanisms governing orderly shutdown and retraction of CD4+ T helper (Th)1 responses remain poorly understood. Here, we show that co... Read more »
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True MicroChIP kit CUT&Tag
Rhesus macaques self-curing from a schistosome infection can displa...
Published: October, 2021
Abstract: The rhesus macaque provides a unique model of acquired immunity against schistosomes, which afflict \>200 million people worldwide. By monitorin... Read more »
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Antibody IP-Star Compact ChIPmentation
Rett syndrome linked to defects in forming the MeCP2/Rbfox/LASRcomp...
Published: October, 2021
Abstract: Rett syndrome (RTT) is a severe neurological disorder and a leading cause of intellectual disability in young females. RTT is mainly caused by muta... Read more »
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Antibody
SETD2-mediated epigenetic regulation of noncanonical Wnt5A duringos...
Published: October, 2021
Abstract: Graphic abstract To define the role of SETD2 in the WNT5a signaling in the context of osteoclastogenesis, we exploited two different models: in vit... Read more »
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Antibody
p300 suppresses the transition of myelodysplastic syndromes to acut...
Published: October, 2021
Abstract: Myelodysplastic syndromes (MDS) are hematopoietic stem and progenitor cell (HSPC) malignancies characterized by ineffective hematopoiesis and an in... Read more »
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Antibody
Tracing the emergence of primordial germ cells from bilaminar disc ...
Published: October, 2021
Abstract: Rabbit embryos develop as bilaminar discs at gastrulation as in humans and most other mammals, whereas rodents develop as egg cylinders. Primordial... Read more »
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Antibody
NR4A1 regulates expression of immediate early genes, suppressingrep...
Published: October, 2021
Abstract: Deregulation of oncogenic signals in cancer triggers replication stress. Immediate early genes (IEGs) are rapidly and transiently expressed followi... Read more »
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Antibody
Establishment of a second generation homozygous CRISPRa human induc...
Published: October, 2021
Abstract: CRISPR/Cas9 technology based on nuclease inactive dCas9 and fused to the heterotrimeric VPR transcriptional activator is a powerful tool to enhance... Read more »
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CRISPR
Regulatory interplay between Vav1, Syk and β-catenin occurs in lung...
Published: October, 2021
Abstract: Vav1 exhibits two signal transducing properties as an adaptor protein and a regulator of cytoskeleton organization through its Guanine nucleotide E... Read more »
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Antibody iDeal ChIP-qPCR ChIP Cross-link Gold
PIWI-mediated control of tissue-specific transposons is essential f...
Published: October, 2021
Abstract: PIWI proteins are known as mediators of transposon silencing in animal germlines but are also found in adult pluripotent stem cells of highly regen... Read more »
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CUT&Tag
MICAL1 regulates actin cytoskeleton organization, directional cellm...
Published: October, 2021
Abstract: The Molecule Interacting with CasL 1 (MICAL1) monooxygenase has emerged as an important regulator of cytoskeleton organization via actin oxidation.... Read more »
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Antibody CRISPR
Genome-Wide Epigenomic Analyses in Patients With Nociceptive and Ne...
Published: September, 2021
Abstract: Nociceptive pain involves the activation of nociceptors without damage to the nervous system, whereas neuropathic pain is related to an alteration ... Read more »
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Premium RRBS Kit DNA Methylation Profiling (RRBS Service) DNA Methylation
Epigenetic control of region-specific transcriptional programs in m...
Published: September, 2021
Abstract: Astrocytes from the cerebral cortex (CTX) and cerebellum (CB) share basic molecular programs, but also form distinct spatial and functional subtype... Read more »
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Antibody
Differential contribution to gene expression prediction of histonem...
Published: September, 2021
Abstract: The ChIP-seq signal of histone modifications at promoters is a good predictor of gene expression in different cellular contexts, but whether this i... Read more »
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Antibody
SUV39 SET domains mediate crosstalk of heterochromatic histone marks.
Published: September, 2021
Abstract: The SUV39 class of methyltransferase enzymes deposits histone H3 lysine 9 di- and trimethylation (H3K9me2/3), the hallmark of constitutive heteroch... Read more »
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Bioruptor Antibody
Chromosomal variations of species revealed by FISH with rDNAs andc...
Published: September, 2021
Abstract: Lycoris species have various chromosome numbers and karyotypes, but all have a constant total number of chromosome major arms. In addition to three... Read more »
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Universal Plant ChIP-seq Kit
Coordination of EZH2 and SOX2 specifies human neural fate decision.
Published: September, 2021
Abstract: Polycomb repressive complexes (PRCs) are essential in mouse gastrulation and specify neural ectoderm in human embryonic stem cells (hESCs), but the... Read more »
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Antibody
PRINCESS: comprehensive detection of haplotype resolved SNVs, SVs,a...
Published: September, 2021
Abstract: Long-read sequencing has been shown to have advantages in structural variation (SV) detection and methylation calling. Many studies focus either on... Read more »
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Megaruptor
Alveolar macrophages from persons living with HIV show impairedepig...
Published: September, 2021
Abstract: Persons living with HIV (PLWH) are at increased risk of tuberculosis (TB). HIV-associated TB is often the result of recent infection with Mycobacte... Read more »
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Microplex Library Preparation kit
Establishing community reference samples, data and call sets forben...
Published: September, 2021
Abstract: The lack of samples for generating standardized DNA datasets for setting up a sequencing pipeline or benchmarking the performance of different algo... Read more »
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Megaruptor
Transcriptome and Methylome Analysis Reveal ComplexCross-Talks betw...
Published: September, 2021
Abstract: BACKGROUND: Most work in endocrinology focus on the action of a single hormone, and very little on the cross-talks between two hormones. Here we ch... Read more »
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MethylCap kit
Interactome Networks of FOSL1 and FOSL2 in Human Th17 Cells.
Published: September, 2021
Abstract: Dysregulated function of Th17 cells has implications in immunodeficiencies and autoimmune disorders. Th17 cell differentiation is orchestrated by a... Read more »
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Antibody
LeafGo: Leaf to Genome, a quick workflow to produce high-quality de...
Published: September, 2021
Abstract: Currently, different sequencing platforms are used to generate plant genomes and no workflow has been properly developed to optimize time, cost, an... Read more »
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Megaruptor
The prolyl-isomerase PIN1 is essential for nuclear Lamin-Bstructure...
Published: September, 2021
Abstract: Chromatin organization plays a crucial role in tissue homeostasis. Heterochromatin relaxation and consequent unscheduled mobilization of transposab... Read more »
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Antibody
DOT1L O-GlcNAcylation promotes its protein stability andMLL-fusion ...
Published: September, 2021
Abstract: Histone lysine methylation functions at the interface of the extracellular environment and intracellular gene expression. DOT1L is a versatile hist... Read more »
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Antibody
WT1 regulates HOXB9 gene expression in a bidirectional way.
Published: September, 2021
Abstract: The homeoboxB9 (HOXB9) gene is necessary for specification of the anterior-posterior body axis during embryonic development and expressed in variou... Read more »
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Antibody
INTS11 regulates hematopoiesis by promoting PRC2 function.
Published: September, 2021
Abstract: INTS11, the catalytic subunit of the Integrator (INT) complex, is crucial for the biogenesis of small nuclear RNAs and enhancer RNAs. However, the ... Read more »
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Antibody Microplex Library Preparation kit

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