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Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Sp1-Induced SETDB1 Overexpression Transcriptionally InhibitsHPGD in...
Published: January, 2022

Abstract: Gastric cancer (GC) has high morbidity and mortality, the cure rate of surgical treatment and drug chemotherapy is not ideal. Therefore, developmen... Read more »

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IP-Star Compact iDeal ChIP-seq Kit for Histones

Three classes of epigenomic regulators converge to hyperactivate th...
Published: January, 2022

Abstract: The formation of a diploid zygote is a highly complex cellular process that is entirely controlled by maternal gene products stored in the egg cyto... Read more »

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Microplex Library Preparation kit

Bone marrow age dictates clonality of smooth muscle-derived cells i...
Published: January, 2022

Abstract: Aging is the predominant risk factor for atherosclerosis, the leading cause of death. Rare smooth muscle cells (SMCs) clonally expand giving rise t... Read more »

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hMeDIP

Mod(mdg4) variants repress telomeric retrotransposon HeT-A byblocki...
Published: January, 2022

Abstract: Telomeres in Drosophila are composed of sequential non-LTR retrotransposons: HeT-A, TART , and TAHRE . Although they are repressed by the piRNA pat... Read more »

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Antibody

The genome sequence of Gymnosoma rotundatum (Linnaeus, 1758), apara...
Published: January, 2022

Abstract: We present a genome assembly from an individual male (Arthropoda; Insecta; Diptera; Tachinidae). The genome sequence is 779 megabases in span. The ... Read more »

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Megaruptor

Integrating SNPs-based genetic risk factor with blood epigenomicres...
Published: January, 2022

Abstract: Arsenic (As) contamination in groundwater is responsible for numerous adverse health outcomes among millions of people. Epigenetic alterations are ... Read more »

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MagMeDIP kit IPure kit

Chemokine switch regulated by TGF-β1 in cancer-associated fibroblas...
Published: January, 2022

Abstract: Combining immunogenic cell death-inducing chemotherapies and PD-1 blockade can generate remarkable tumor responses. It is now well established that... Read more »

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Antibody IP-Star Compact

Development and inter-laboratory validation of the VISAGE enhanced ...
Published: January, 2022

Abstract: The analysis of DNA methylation has become an established method for chronological age estimation. This has triggered interest in the forensic comm... Read more »

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Premium Bisulfite Kit

27-Hydroxycholesterol, The Estrogen Receptor Modulator, AltersDNA M...
Published: January, 2022

Abstract: 27-hydroxycholesterol (27-HC) is the first known endogenous selective estrogen receptor modulator (SERM), and its elevation from normal levels is c... Read more »

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Antibody

Loss of KMT2C reprograms the epigenomic landscape in hPSCsresulting...
Published: January, 2022

Abstract: Germline or somatic variation in the family of KMT2 lysine methyltransferases have been associated with a variety of congenital disorders and cance... Read more »

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Antibody

Single cell quantification of ribosome occupancy in early mouse dev...
Published: December, 2021

Abstract: Technological limitations precluded transcriptome-wide analyses of translation at single cell resolution. To solve this challenge, we developed a n... Read more »

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D-Plex small RNA-seq

Single cell quantification of ribosome occupancy in early mousedeve...
Published: December, 2021

Abstract: Technological limitations precluded transcriptome-wide analyses of translation at single cell resolution. To solve this challenge, we developed a n... Read more »

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D-Plex small RNA-seq

Androgen receptor and MYC equilibration centralizes on developmenta...
Published: December, 2021

Abstract: Androgen receptor (AR) in prostate cancer (PCa) can drive transcriptional repression of multiple genes including MYC, and supraphysiological androg... Read more »

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Antibody

A predominant enhancer co-amplified with the oncogene is necessary...
Published: December, 2021

Abstract: Amplification and overexpression of the SOX2 oncogene represent a hallmark of squamous cancers originating from diverse tissue types. Here, we find... Read more »

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CRISPR

The long noncoding RNA H19 regulates tumor plasticity inneuroendocr...
Published: December, 2021

Abstract: Neuroendocrine (NE) prostate cancer (NEPC) is a lethal subtype of castration-resistant prostate cancer (PCa) arising either de novo or from transdi... Read more »

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Antibody

Sevoflurane induces inflammation in primary hippocampal neurons byr...
Published: December, 2021

Abstract: Postoperative cognitive dysfunction (POCD) is a normal condition that develops after surgery with anesthesia, leading to deterioration of cognitive... Read more »

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iDeal ChIP-qPCR

Epigenetic Silencing of OR and TAS2R Genes Expression inHuman Orbit...
Published: December, 2021

Abstract: Modulation of brain olfactory (OR) and taste receptors (TASR) expression was recently reported in neurological diseases. We explored the possible e... Read more »

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Antibody

Gene bookmarking by the heat shock transcription factor programs th...
Published: December, 2021

Abstract: Maternal stress can have long-lasting epigenetic effects on offspring. To examine how epigenetic changes are triggered by stress, we examined the e... Read more »

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Antibody

Examining age-dependent DNA methylation patterns and gene expressio...
Published: December, 2021

Abstract: DNA methylation is a well-characterized epigenetic modification involved in numerous molecular and cellular functions. Methylation patterns have al... Read more »

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MagMeDIP kit

Cancer Detection and Classification by CpG Island Hypermethylation ...
Published: November, 2021

Abstract: Cell-free DNA (cfDNA) methylation has emerged as a promising biomarker for early cancer detection, tumor type classification, and treatment respons... Read more »

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MethylCap kit

Epromoters function as a hub to recruit key transcription factorsre...
Published: November, 2021

Abstract: Gene expression is controlled by the involvement of gene-proximal (promoters) and distal (enhancers) regulatory elements. Our previous results demo... Read more »

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Antibody Microplex Library Preparation kit

Soluble guanylate cyclase signalling mediates etoposide resistance ...
Published: November, 2021

Abstract: Small cell lung cancer (SCLC) has a 5-year survival rate of \<7\%. Rapid emergence of acquired resistance to standard platinum-etoposide chemoth... Read more »

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ChIP Cross-link Gold

Decreased PRC2 activity supports the survival of basal-like breastc...
Published: November, 2021

Abstract: Breast cancer (BC) is the most common cancer occurring in women but also rarely develops in men. Recent advances in early diagnosis and development... Read more »

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Microplex Library Preparation kit

Comparing the epigenetic landscape in myonuclei purified with a PCM...
Published: November, 2021

Abstract: Muscle cells have different phenotypes adapted to different usage, and can be grossly divided into fast/glycolytic and slow/oxidative types. While ... Read more »

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Antibody

Reference genome assembly of the big berry Manzanita (Arctostaphylo...
Published: November, 2021

Abstract: Arctostaphylos (Ericaceae) species, commonly known as manzanitas, are an invaluable fire-adapted chaparral clade in the California Floristic Provin... Read more »

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Megaruptor

Conditional depletion of transcriptional kinases Ctk1 and Bur1 ande...
Published: November, 2021

Abstract: From yeast to humans, pre-mRNA splicing occurs mainly co-transcriptionally, with splicing and transcription functionally coupled such that they inf... Read more »

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Antibody

ATRX regulates glial identity and the tumor microenvironment inIDH-...
Published: November, 2021

Abstract: Background Recent single-cell transcriptomic studies report that IDH-mutant gliomas share a common hierarchy of cellular phenotypes, independent of... Read more »

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Antibody CUT&Tag

Ago1 controls myogenic differentiation by regulating eRNA-mediatedC...
Published: November, 2021

Abstract: The role of chromatin-associated RNAi components in the nucleus of mammalian cells and in particular in the context of developmental programs remai... Read more »

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Microplex Library Preparation kit

Extensive NEUROG3 occupancy in the human pancreatic endocrine gener...
Published: November, 2021

Abstract: OBJECTIVE: Mice lacking the bHLH transcription factor (TF) Neurog3 do not form pancreatic islet cells, including insulin-secreting beta cells, the ... Read more »

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Microplex Library Preparation kit

Characteristics of Immediate-Early 2 (IE2) and UL84 Proteins in UL8...
Published: October, 2021

Abstract: Human cytomegalovirus (HCMV) immediate-early 2 (IE2) protein is the major transactivator for viral gene expression and is required for lytic replic... Read more »

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iDeal ChIP-seq Kit for Transcription Factors

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