Diagenode

Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Regulation of adipocyte differentiation by the zinc finger protein ...
Published: July, 2011

Abstract: Zinc finger proteins constitute the largest family of transcription regulators in eukaryotes. These factors are involved in diverse processes in ma... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Negative regulation of HIV-1 transcription by a heterodimeric NF-κB...
Published: July, 2011

Abstract: Signal transducers and activator of transcription (STAT) proteins are often constitutively activated in leukocytes of HIV-1(+) individuals, which f... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Rtt107 is required for recruitment of the SMC5/6 complex to DNA dou...
Published: July, 2011

Abstract: Genome integrity is maintained by a network of DNA damage response pathways, including checkpoints and DNA repair processes. In Saccharomyces cerev... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Defective GATA-3 expression in Th2 LCR-deficient mice.
Published: July, 2011

Abstract: Th2 cell differentiation is critically influenced by transcription factor GATA-3 and by various cis-acting elements including enhancers, silencers ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Transcription factors KLF1 and KLF2 positively regulate embryonic a...
Published: July, 2011

Abstract: Krüppel-like factors (KLFs) control cell differentiation and embryonic development. KLF1 (erythroid Krüppel-like factor) plays essential roles in e... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Cap2-HAP complex is a critical transcriptional regulator that has d...
Published: July, 2011

Abstract: Iron homeostasis is highly regulated in organisms across evolutionary time scale as iron is essential for various cellular processes. In a computat... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus
Hyperexpansion of GAA repeats affects post-initiation steps of FXN ...
Published: July, 2011

Abstract: Friedreich's ataxia (FRDA) is caused by biallelic expansion of GAA repeats leading to the transcriptional silencing of the frataxin (FXN) gene. The... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Human mediator subunit MED26 functions as a docking site for transc...
Published: July, 2011

Abstract: Promoter-proximal pausing by initiated RNA polymerase II (Pol II) and regulated release of paused polymerase into productive elongation has emerged... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Transcription factor T-bet represses expression of the inhibitory r...
Published: July, 2011

Abstract: T cell exhaustion has a major role in failure to control chronic infection. High expression of inhibitory receptors, including PD-1, and the inabil... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Cell type-specific DNA methylation at intragenic CpG islands in the...
Published: July, 2011

Abstract: Human and mouse genomes contain a similar number of CpG islands (CGIs), which are discrete CpG-rich DNA sequences associated with transcription sta... Read more »

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DNA shearing Bioruptor
Extensive and coordinated transcription of noncoding RNAs within ce...
Published: July, 2011

Abstract: Transcription of long noncoding RNAs (lncRNAs) within gene regulatory elements can modulate gene activity in response to external stimuli, but the ... Read more »

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Bioruptor
H3K9 histone acetylation predicts pluripotency and reprogramming ca...
Published: July, 2011

Abstract: The pluripotent genome is characterized by unique epigenetic features and a decondensed chromatin conformation. However, the relationship between e... Read more »

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Bioruptor Chromatin Shearing ChIP-seq
Hyphal development in Candida albicans requires two temporally link...
Published: July, 2011

Abstract: Phenotypic plasticity is common in development. For Candida albicans, the most common cause of invasive fungal infections in humans, morphological ... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
RETINOBLASTOMA-RELATED PROTEIN controls the transition to autotroph...
Published: July, 2011

Abstract: Seedling establishment is a crucial phase during plant development when the germinating heterotrophic embryo switches to autotrophic growth and dev... Read more »

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LowCell ChIP kit
Activation of group II metabotropic glutamate receptors promotes DN...
Published: July, 2011

Abstract: Activation of group II metabotropic glutamate receptors (mGlu2 and -3 receptors) has shown a potential antipsychotic activity, yet the underlying m... Read more »

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MagMeDIP kit
Association of Rex-1 to target genes supports its interaction with ...
Published: July, 2011

Abstract: Rex-1/Zfp42 displays a remarkably restricted pattern of expression in preimplantation embryos, primary spermatocytes, and undifferentiated mouse em... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
SeqGene: a comprehensive software solution for mining exome- and tr...
Published: June, 2011

Abstract: BACKGROUND: The popularity of massively parallel exome and transcriptome sequencing projects demands new data mining tools with a comprehensive set... Read more »

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DNA shearing Bioruptor
DNA methylation status predicts cell type-specific enhancer activity
Published: June, 2011

Abstract: Cell-selective glucocorticoid receptor (GR) binding to distal regulatory elements is associated with cell type-specific regions of locally accessib... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
5-Hydroxymethylcytosine is associated with enhancers and gene bodie...
Published: June, 2011

Abstract: BACKGROUND: 5-Hydroxymethylcytosine (5hmC) was recently found to be abundantly present in certain cell types, including embryonic stem cells. There... Read more »

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Antibody
Occupancy of chromatin organizers in the Epstein-Barr virus genome.
Published: June, 2011

Abstract: The human CCCTC-binding factor, CTCF, regulates transcription of the double-stranded DNA genomes of herpesviruses. The architectural complex cohesi... Read more »

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Bioruptor Chromatin Shearing ChIP-seq
Early-stage formation of an epigenetic field defect in a mouse coli...
Published: June, 2011

Abstract: Epigenetic fields for cancerization are involved in development of human cancers, especially those associated with inflammation and multiple occurr... Read more »

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Antibody
Mutations in ZBTB24 are associated with immunodeficiency, centromer...
Published: June, 2011

Abstract: Autosomal-recessive immunodeficiency, centromeric instability, and facial anomalies (ICF) syndrome is mainly characterized by recurrent, often fata... Read more »

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DNA shearing Bioruptor
Human teneurin-1 is a direct target of the homeobox transcription f...
Published: June, 2011

Abstract: BACKGROUND: Teneurin-1 is a member of a family of type II transmembrane proteins conserved from C.elegans to vertebrates. Teneurin expression in ve... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Effects of epigenetic-based anti-cancer drugs in leukemia and multi...
Published: June, 2011

Abstract: Here, we focused on epigenetic changes in leukemia and multiple myeloma (MM) cells. We show how the histone signature, DNA methylation, and levels ... Read more »

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MeDIP kit
Maps of open chromatin guide the functional follow-up of genome-wid...
Published: June, 2011

Abstract: Turning genetic discoveries identified in genome-wide association (GWA) studies into biological mechanisms is an important challenge in human genet... Read more »

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Bioruptor Chromatin Shearing
Coxsackie and adenovirus receptor is a target and a mediator of est...
Published: June, 2011

Abstract: The involvement of the coxsackie and adenovirus receptor (CAR), an adhesion molecule known to be the main determinant of adenovirus transduction of... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Enhancer of Zeste 2 (EZH2) is up-regulated in malignant gliomas and...
Published: June, 2011

Abstract: AIMS: Proteins of the Polycomb repressive complex 2 (PRC2) are epigenetic gene silencers and are involved in tumour development. Their oncogenic fu... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Antibody
A genome-wide search for promoters that respond to increased MYCN r...
Published: June, 2011

Abstract: MYCN is a major driver of neuroblastoma tumorigenesis and MYCN amplification is the worst prognostic indicator of aggressive NB. To identify potent... Read more »

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Bioruptor Chromatin Shearing ChIP-seq
How chromatin is remodelled during DNA repair of UV-induced DNA dam...
Published: June, 2011

Abstract: Global genome nucleotide excision repair removes DNA damage from transcriptionally silent regions of the genome. Relatively little is known about t... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR
Dynamic chromatin localization of Sirt6 shapes stress- and aging-re...
Published: June, 2011

Abstract: The sirtuin Sirt6 is a NAD-dependent histone deacetylase that is implicated in gene regulation and lifespan control. Sirt6 can interact with the st... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

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