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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Maps of open chromatin guide the functional follow-up of genome-wid...
Published: June, 2011
Abstract: Turning genetic discoveries identified in genome-wide association (GWA) studies into biological mechanisms is an important challenge in human genet... Read more »
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Bioruptor Chromatin Shearing
Coxsackie and adenovirus receptor is a target and a mediator of est...
Published: June, 2011
Abstract: The involvement of the coxsackie and adenovirus receptor (CAR), an adhesion molecule known to be the main determinant of adenovirus transduction of... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Enhancer of Zeste 2 (EZH2) is up-regulated in malignant gliomas and...
Published: June, 2011
Abstract: AIMS: Proteins of the Polycomb repressive complex 2 (PRC2) are epigenetic gene silencers and are involved in tumour development. Their oncogenic fu... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Antibody
A genome-wide search for promoters that respond to increased MYCN r...
Published: June, 2011
Abstract: MYCN is a major driver of neuroblastoma tumorigenesis and MYCN amplification is the worst prognostic indicator of aggressive NB. To identify potent... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
How chromatin is remodelled during DNA repair of UV-induced DNA dam...
Published: June, 2011
Abstract: Global genome nucleotide excision repair removes DNA damage from transcriptionally silent regions of the genome. Relatively little is known about t... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Dynamic chromatin localization of Sirt6 shapes stress- and aging-re...
Published: June, 2011
Abstract: The sirtuin Sirt6 is a NAD-dependent histone deacetylase that is implicated in gene regulation and lifespan control. Sirt6 can interact with the st... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Mediator influences telomeric silencing and cellular life span.
Published: June, 2011
Abstract: The Mediator complex is required for the regulated transcription of nearly all RNA polymerase II-dependent genes. Here we demonstrate a new role fo... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Human imprinted retrogenes exhibit non-canonical imprint chromatin ...
Published: June, 2011
Abstract: Imprinted retrotransposed genes share a common genomic organization including a promoter-associated differentially methylated region (DMR) and a po... Read more »
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DNA shearing Bioruptor
Circumventing heterozygosity: sequencing the amplified genome of a ...
Published: June, 2011
Abstract: Heterozygosity is a major challenge to efficient, high-quality genomic assembly and to the full genomic survey of polymorphism and divergence. In D... Read more »
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DNA shearing Bioruptor
LSD1 regulates the balance between self-renewal and differentiation...
Published: June, 2011
Abstract: We identify LSD1 (lysine-specific demethylase 1; also known as KDM1A and AOF2) as a key histone modifier that participates in the maintenance of pl... Read more »
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Antibody
H3.5 is a novel hominid-specific histone H3 variant that is specifi...
Published: June, 2011
Abstract: The incorporation of histone variants into chromatin plays an important role for the establishment of particular chromatin states. Six human histon... Read more »
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Antibody H3K4me3 (C15410003)
Pre-TCR signaling and CD8 gene bivalent chromatin resolution during...
Published: June, 2011
Abstract: The CD8 gene is silent in CD4(-)CD8(-) double-negative thymocytes, expressed in CD4(+)CD8(+) double-positive cells, and silenced in cells committin... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Reversible epigenetic fingerprint-mediated glutathione-S-transferas...
Published: June, 2011
Abstract: Glutathione-S-transferase P1 (GSTP1) gene is commonly silenced by CpG island promoter hypermethylation in prostate, breast, and liver cancers. Howe... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Cell Lysis Enzymatic Assay
Analysis of the GAD1 promoter: trans-acting factors and DNA methyla...
Published: June, 2011
Abstract: GAD67 corresponds to one of two enzymes that decarboxylates glutamate to produce γ-aminobutyric acid, the main inhibitory neurotransmitter in the m... Read more »
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DNA shearing Bioruptor
Differential nuclear localisation and promoter occupancy play a rol...
Published: May, 2011
Abstract: The glucocorticoid receptor (GR) is a ligand-activated transcription factor for which a number of endogenous and synthetic ligands exist. A key que... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Arginine and glutamate-rich 1 (ARGLU1) interacts with mediator subu...
Published: May, 2011
Abstract: Estrogen receptor is a nuclear receptor superfamily member of transcriptional activators that regulate gene expression by recruiting diverese trans... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
RNF20 inhibits TFIIS-facilitated transcriptional elongation to supp...
Published: May, 2011
Abstract: hBRE1/RNF20 is the major E3 ubiquitin ligase for histone H2B. RNF20 depletion causes a global reduction of monoubiquitylated H2B (H2Bub) levels and... Read more »
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Bioruptor Cell Lysis
Cohesin mediates chromatin interactions that regulate mammalian β-g...
Published: May, 2011
Abstract: The β-globin locus undergoes dynamic chromatin interaction changes in differentiating erythroid cells that are thought to be important for proper g... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
TET1 and hydroxymethylcytosine in transcription and DNA methylation...
Published: May, 2011
Abstract: Enzymes catalysing the methylation of the 5-position of cytosine (mC) have essential roles in regulating gene expression and maintaining cellular i... Read more »
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MethylCap
Caenorhabditis elegans chromatin-associated proteins SET-2 and ASH-...
Published: May, 2011
Abstract: Methylation of histone H3 lysine 4 (H3K4me), a mark associated with gene activation, is mediated by SET1 and the related mixed lineage leukemia (ML... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Antibody
Interaction between FGFR-2, STAT5, and progesterone receptors in br...
Published: May, 2011
Abstract: Fibroblast growth factor (FGF) receptor 2 (FGFR-2) polymorphisms have been associated with an increase in estrogen receptor and progesterone recept... Read more »
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HighCell ChIP kit
AP-2c regulates oestrogen receptor-mediated long-range chromatin in...
Published: May, 2011
Abstract: Oestrogen receptor α (ERα) is key player in the progression of breast cancer. Recently, the cistrome and interactome of ERα were mapped in breast c... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Mapping and analysis of chromatin state dynamics in nine human cell...
Published: May, 2011
Abstract: Chromatin profiling has emerged as a powerful means of genome annotation and detection of regulatory activity. The approach is especially well suit... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Requirement for Dot1l in murine postnatal hematopoiesis and leukemo...
Published: May, 2011
Abstract: Disruptor of telomeric silencing 1-like (Dot1l) is a histone 3 lysine 79 methyltransferase. Studies of constitutive Dot1l knockout mice show that D... Read more »
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Bioruptor Cell Lysis Western Blot
LIF, a Novel STAT5-Regulated Gene, Is Aberrantly Expressed in Myelo...
Published: May, 2011
Abstract: A search for genes potentially regulated by STAT5 identified leukemia inhibitory factor (LIF) as a good candidate. Using various experimental appro... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Histone H3K4 trimethylation by MLL3 as part of ASCOM complex is cri...
Published: May, 2011
Abstract: The nuclear receptor Farnesoid x receptor (FXR) is a critical regulator of multiple genes involved in bile acid homeostasis. The coactivators attra... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Epigenetic profile of the euchromatic region of human Y chromosome.
Published: May, 2011
Abstract: The genome of a multi-cellular organism acquires various functional capabilities in different cell types by means of distinct chromatin modificatio... Read more »
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Bioruptor Chromatin Shearing Antibody LowCell ChIP kit
NF-kB and c-Jun induce the expression of the oncogenic miR-221 and ...
Published: May, 2011
Abstract: MicroRNAs (miRNAs) are potent negative regulators of gene expression involved in all aspects of cell biology. They finely modulate virtually all ph... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Functional analysis of KAP1 genomic recruitment.
Published: May, 2011
Abstract: TRIM28 (KAP1) is upregulated in many cancers and has been implicated in both transcriptional activation and repression. Using chromatin immunopreci... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
JAG2 induction in hypoxic tumor cells alters Notch signaling and en...
Published: May, 2011
Abstract: Several studies have revealed links between hypoxia and activation of Notch in solid tumors. While most reports have focused on intracellular domai... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR

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    May 6-May 9, 2024
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    London, UK
    May 21-May 24, 2024
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    Vienna, Austria
    May 28-May 29, 2024
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