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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Epigenetic and molecular signature of human umbilical cord blood-de...
Published: April, 2013
Abstract: In the context of cell therapy, the epigenetic status of core stemness transcription factor (STF) genes regulating the cell proliferation/different... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus
Epigenetic upregulation of lncRNAs at 13q14.3 in leukemia is linked...
Published: April, 2013
Abstract: Non-coding RNAs are much more common than previously thought. However, for the vast majority of non-coding RNAs, the cellular function remains enig... Read more »
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DNA shearing Bioruptor Chromatin Shearing ChIP-qPCR
Intrinsic epigenetic regulation of the D4Z4 macrosatellite repeat i...
Published: April, 2013
Abstract: Facioscapulohumeral dystrophy (FSHD) is a progressive muscular dystrophy caused by decreased epigenetic repression of the D4Z4 macrosatellite repea... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
DNA double-strand breaks coupled with PARP1 and HNRNPA2B1 binding s...
Published: April, 2013
Abstract: Genome instability plays a key role in multiple biological processes and diseases, including cancer. Genome-wide mapping of DNA double-strand break... Read more »
Multiple IRF- and NFkB-sites cooperate in mediating cell type- and ...
Published: April, 2013
Abstract: CD83 is one of the best-known surface marker for fully mature dendritic cells (DCs) and its cell type- and maturation-specific regulation makes the... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Mutations in the nucleolar phosphoprotein, nucleophosmin, promote t...
Published: March, 2013
Abstract: Myeloid ELF1-like factor (MEF/ELF4), a member of the ETS transcription factors, can function as an oncogene in murine cancer models and is overexpr... Read more »
Single-cell dynamics of genome-nuclear lamina interactions.
Published: March, 2013
Abstract: The nuclear lamina (NL) interacts with hundreds of large genomic regions termed lamina associated domains (LADs). The dynamics of these interaction... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
The role of proteasome beta subunits in gastrin-mediated transcript...
Published: March, 2013
Abstract: The hormone gastrin physiologically regulates gastric acid secretion and also contributes to maintaining gastric epithelial architecture by regulat... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus
Topoisomerase IIα promotes activation of RNA polymerase I transcrip...
Published: March, 2013
Abstract: Type II DNA topoisomerases catalyse DNA double-strand cleavage, passage and re-ligation to effect topological changes. There is considerable intere... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR IPure kit
Epigenetic reactivation of Nrf2 in murine prostate cancer TRAMP C1 ...
Published: March, 2013
Abstract: Cancer development has been linked to epigenetic modifications of cancer oncogenes and tumor suppressor genes; in advanced metastatic cancers, seve... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR MagMeDIP kit
The BEN domain is a novel sequence-specific DNA-binding domain cons...
Published: March, 2013
Abstract: We recently reported that Drosophila Insensitive (Insv) promotes sensory organ development and has activity as a nuclear corepressor for the Notch ... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Quality evaluation of methyl binding domain based kits for enrichme...
Published: March, 2013
Abstract: DNA-methylation is an important epigenetic feature in health and disease. Methylated sequence capturing by Methyl Binding Domain (MBD) based enrich... Read more »
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MethylCap
Fission yeast CSL proteins function as transcription factors.
Published: March, 2013
Abstract: BACKGROUND: Transcription factors of the CSL (CBF1/RBP-Jk/Suppressor of Hairless/LAG-1) family are key regulators of metazoan development and funct... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
PRC1 coordinates timing of sexual differentiation of female primord...
Published: March, 2013
Abstract: In mammals, sex differentiation of primordial germ cells (PGCs) is determined by extrinsic cues from the environment. In mouse female PGCs, express... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Genomic evidence for island population conversion resolves conflict...
Published: March, 2013
Abstract: Despite extensive genetic analysis, the evolutionary relationship between polar bears (Ursus maritimus) and brown bears (U. arctos) remains unclear... Read more »
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DNA shearing Bioruptor
CPEB1 coordinates alternative 3'-UTR formation with translational r...
Published: March, 2013
Abstract: More than half of mammalian genes generate multiple messenger RNA isoforms that differ in their 3' untranslated regions (3' UTRs) and therefore in ... Read more »
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Bioruptor Cell Lysis Western Blot
Shift from extracellular signal-regulated kinase to AKT/cAMP respon...
Published: March, 2013
Abstract: Spinal muscular atrophy (SMA), a recessive neurodegenerative disease, is characterized by the selective loss of spinal motor neurons. No available ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Adipose subtype-selective recruitment of TLE3 or Prdm16 by PPARγ sp...
Published: March, 2013
Abstract: Transcriptional effectors of white adipocyte-selective gene expression have not been described. Here we show that TLE3 is a white-selective cofacto... Read more »
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Master Mix
Epigenetic hierarchy within the MAGEA1 cancer-germline gene: promot...
Published: March, 2013
Abstract: Gene MAGEA1 belongs to a group of human germline-specific genes that rely on DNA methylation for repression in somatic tissues. Many of these genes... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Antibody
Acetylation limits 53BP1 association with damaged chromatin to prom...
Published: March, 2013
Abstract: The pathogenic sequelae of BRCA1 mutation in human and mouse cells are mitigated by concomitant deletion of 53BP1, which binds histone H4 dimethyla... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
H2A.Z and H2B.Z double-variant nucleosomes define intergenic region...
Published: March, 2013
Abstract: Histone variants are important components of eukaryotic chromatin and can alter chromatin structure to confer specialized functions. H2B variant hi... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Myod and H19-Igf2 locus interactions are required for diaphragm for...
Published: March, 2013
Abstract: The myogenic regulatory factor Myod and insulin-like growth factor 2 (Igf2) have been shown to interact in vitro during myogenic differentiation. I... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR HighCell ChIP kit
Naive pluripotency is associated with global DNA hypomethylation.
Published: March, 2013
Abstract: Naive pluripotent embryonic stem cells (ESCs) and embryonic germ cells (EGCs) are derived from the preimplantation epiblast and primordial germ cel... Read more »
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Antibody 5mC (C15200081)
Chromatin immunoprecipitation of adult murine cardiomyocytes.
Published: March, 2013
Abstract: This unit describes a streamlined two-step protocol for the isolation of adult murine cardiomyocytes with subsequent Chromatin ImmunoPrecipitation ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Genome-wide control of RNA polymerase II activity by cohesin.
Published: March, 2013
Abstract: Cohesin is a well-known mediator of sister chromatid cohesion, but it also influences gene expression and development. These non-canonical roles of... Read more »
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Bioruptor Chromatin Shearing
Activating RNAs associate with Mediator to enhance chromatin archit...
Published: February, 2013
Abstract: Recent advances in genomic research have revealed the existence of a large number of transcripts devoid of protein-coding potential in multiple org... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
H3K4me3 interactions with TAF3 regulate preinitiation complex assem...
Published: February, 2013
Abstract: Histone modifications regulate chromatin-dependent processes, yet the mechanisms by which they contribute to specific outcomes remain unclear. H3K4... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
H2-independent growth of the hydrogenotrophic methanogen Methanococ...
Published: February, 2013
Abstract: UNLABELLED: Hydrogenotrophic methanogenic Archaea require reduced ferredoxin as an anaplerotic source of electrons for methanogenesis. H(2) oxidati... Read more »
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DNA shearing Bioruptor
Endogenous purification reveals GREB1 as a key estrogen receptor re...
Published: February, 2013
Abstract: Estrogen receptor-α (ER) is the driving transcription factor in most breast cancers, and its associated proteins can influence drug response, but d... Read more »
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Bioruptor Cell Lysis
Dynamics of 5-hydroxymethylcytosine and chromatin marks in Mammalia...
Published: February, 2013
Abstract: DNA methylation in mammals is highly dynamic during germ cell and preimplantation development but is relatively static during the development of so... Read more »
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Antibody

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