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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

LIN9, a subunit of the DREAM complex, regulates mitotic gene expres...
Published: May, 2013
Abstract: The DREAM complex plays an important role in regulation of gene expression during the cell cycle. We have previously shown that the DREAM subunit L... Read more »
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Bioruptor Chromatin Shearing
Sirt1 ablation promotes stress-induced loss of epigenetic and genom...
Published: May, 2013
Abstract: The (histone) deacetylase Sirt1 is a mediator of genomic and epigenetic maintenance, both of which are critical aspects of stem cell homeostasis an... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Transcriptional regulation of insulin-degrading enzyme modulates mi...
Published: May, 2013
Abstract: Studies of post-mortem brains from Alzheimer disease patients suggest that oxidative damage induced by mitochondrial amyloid β (mitAβ) accumulation... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Estrogen-dependent dynamic profile of eNOS-DNA associations in pros...
Published: May, 2013
Abstract: In previous work we have documented the nuclear translocation of endothelial NOS (eNOS) and its participation in combinatorial complexes with Estro... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Methyl donor supplementation blocks the adverse effects of maternal...
Published: May, 2013
Abstract: Maternal consumption of a high fat diet during pregnancy increases the offspring risk for obesity. Using a mouse model, we have previously shown th... Read more »
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MagMeDIP kit Antibody 5mC (C15200081)
RNA helicase Ddx5 and the noncoding RNA SRA act as coactivators in ...
Published: May, 2013
Abstract: Notch signaling plays a pivotal role in embryonic and postnatal development. Upon binding of a Notch ligand, proteolytic cleavage events liberate t... Read more »
Region of difference 4 in alpine Mycobacterium caprae isolates indi...
Published: May, 2013
Abstract: The lack of complete genome sequence information for Mycobacterium caprae complicates a robust differentiation of M. caprae and Mycobacterium bovis... Read more »
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DNA shearing Bioruptor Bioruptor Plus
Sulforaphane enhances Nrf2 expression in prostate cancer TRAMP C1 c...
Published: May, 2013
Abstract: Growing evidence suggests epigenetic alteration is involved during the development and progression of prostate cancer. Previously, we found Nrf2, a... Read more »
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DNA shearing Bioruptor Chromatin Shearing ChIP-qPCR MagMeDIP kit
Epigenetic regulation of cholinergic receptor M1 (CHRM1) by histone...
Published: May, 2013
Abstract: Huntington's disease (HD) is an autosomal dominant neurodegenerative disease caused by an expanded trinucleotide CAG repeat in the gene coding for ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Developmentally programmed 3' CpG island methylation confers tissue...
Published: May, 2013
Abstract: During development, a small but significant number of CpG islands (CGIs) become methylated. The timing of developmentally programmed CGI methylatio... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Use of red autofluorescence for monitoring prodiginine biosynthesis.
Published: May, 2013
Abstract: Prodigiosin-like pigments or prodiginines (PdGs) are promising drugs owing to their reported antitumor, antibiotic, and immunosuppressive activitie... Read more »
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Bioruptor Cell Lysis
Epigenetic changes in renal genes dysregulated in mouse and rat mod...
Published: May, 2013
Abstract: Epigenetic processes are increasingly being recognized as factors in the pathophysiology of diabetes complications, but few chromatin studies have ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
G9a is transactivated by C/EBPβ to facilitate mitotic clonal expans...
Published: May, 2013
Abstract: In 3T3-L1 preadipocyte differentiation, the CCAAT/enhancer-binding protein-β (C/EBPβ) is an important early transcription factor that activates cel... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
The genome of the platyfish, Xiphophorus maculatus, provides insigh...
Published: May, 2013
Abstract: Several attributes intuitively considered to be typical mammalian features, such as complex behavior, live birth and malignant disease such as canc... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
A Common histone modification code on C4 genes in maize and its con...
Published: May, 2013
Abstract: C4 photosynthesis evolved more than 60 times independently in different plant lineages. Each time, multiple genes were recruited into C4 metabolism... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Satb1 regulates the self-renewal of hematopoietic stem cells by pro...
Published: May, 2013
Abstract: How hematopoietic stem cells (HSCs) coordinate the regulation of opposing cellular mechanisms such as self-renewal and differentiation commitment r... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR LowCell ChIP kit
Progesterone receptors induce FOXO1-dependent senescence in ovarian...
Published: May, 2013
Abstract: Loss of nuclear progesterone receptors (PR) and low circulating progesterone levels are associated with increased ovarian cancer (OC) risk. However... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Liver x receptors protect from development of prostatic intra-epith...
Published: May, 2013
Abstract: LXR (Liver X Receptors) act as "sensor" proteins that regulate cholesterol uptake, storage, and efflux. LXR signaling is known to influence prolife... Read more »
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Antibody
Differential transcript isoform usage pre- and post-zygotic genome ...
Published: May, 2013
Abstract: BACKGROUND: Zebrafish embryos are transcriptionally silent until activation of the zygotic genome during the 10th cell cycle. Onset of transcriptio... Read more »
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Antibody
First evidence of DNA methylation in insect Tribolium castaneum: en...
Published: May, 2013
Abstract: DNA methylation has been studied in many eukaryotic organisms, in particular vertebrates, and was implicated in developmental and phenotypic variat... Read more »
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Antibody
G-quadruplex structures are stable and detectable in human genomic ...
Published: April, 2013
Abstract: The G-quadruplex is an alternative DNA structural motif that is considered to be functionally important in the mammalian genome for transcriptional... Read more »
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DNA shearing Bioruptor
Heterochromatin protein 1 promotes self-renewal and triggers regene...
Published: April, 2013
Abstract: Adult stem cells (ASCs) capable of self-renewal and differentiation confer the potential of tissues to regenerate damaged parts. Epigenetic regulat... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Coordinate changes in histone modifications, mRNA levels, and metab...
Published: April, 2013
Abstract: Lipotoxicity is a presumed pathogenetic process whereby elevated circulating and stored lipids in type 2 diabetes cause pancreatic β-cell failure. ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Master Mix
Balancing of histone H3K4 methylation states by the Kdm5c/SMCX hist...
Published: April, 2013
Abstract: The functional organization of eukaryotic genomes correlates with specific patterns of histone methylations. Regulatory regions in genomes such as ... Read more »
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Bioruptor Chromatin Shearing ChIP-seq Antibody
A proteomic characterization of factors enriched at nascent DNA mol...
Published: April, 2013
Abstract: DNA replication is facilitated by multiple factors that concentrate in the vicinity of replication forks. Here, we developed an approach that combi... Read more »
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Bioruptor Chromatin Shearing
Genome-wide analysis reveals TET- and TDG-dependent 5-methylcytosin...
Published: April, 2013
Abstract: TET dioxygenases successively oxidize 5-methylcytosine (5mC) in mammalian genomes to 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC), and 5-... Read more »
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DNA shearing Bioruptor
Placing the HIRA histone chaperone complex in the chromatin landscape.
Published: April, 2013
Abstract: The HIRA chaperone complex, comprised of HIRA, UBN1, and CABIN1, collaborates with histone-binding protein ASF1a to incorporate histone variant H3.... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
A vitamin D receptor/SMAD genomic circuit gates hepatic fibrotic re...
Published: April, 2013
Abstract: Liver fibrosis is a reversible wound-healing response involving TGFβ1/SMAD activation of hepatic stellate cells (HSCs). It results from excessive d... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
An Orally Bioavailable Chemical Probe of the Lysine Methyltransfera...
Published: April, 2013
Abstract: EZH2 or EZH1 is the catalytic subunit of the polycomb repressive complex 2 that catalyzes methylation of histone H3 lysine 27 (H3K27). The trimethy... Read more »
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Antibody
Mechanism of Polycomb recruitment to CpG islands revealed by inheri...
Published: April, 2013
Abstract: How the transcription repressing complex Polycomb interacts with transcriptional regulators at housekeeping genes in somatic cells is not well unde... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR

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