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Mass Spectrometry – Using the Bioruptor® to lyse C. Elegans for biochemical and proteomics analysis

Prasad Kasturi and F Ulrich Hartl from the Department of Cellular Biochemistry at the Max Planck Institute for Biochemistry, Martinsried, Germany are using the Bioruptor® for their research using C. elegans, a powerful metazoan model system to study and understand fundamental problems in biology. Traditionally C. elegans research has focused mainly on genetics. However, recent studies suggest that C. elegans can also be a facile system for biochemistry. Tagged proteins can be expressed in vivo and interacting partners can be identified using various biochemical approaches. In addition, protein networks and pathways can be identified by combining genetic screens with biochemistry.

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