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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

ChIP-seq protocol for sperm cells and embryos to assess environment...
Published: June, 2021
Abstract: In the field of epigenetic inheritance, delineating molecular mechanisms implicated in the transfer of paternal environmental conditions to descend... Read more »
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Antibody
Familial thrombocytopenia due to a complex structural variant resul...
Published: June, 2021
Abstract: Advances in genome sequencing have resulted in the identification of the causes for numerous rare diseases. However, many cases remain unsolved wit... Read more »
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Megaruptor
The American lobster genome reveals insights on longevity, neural, ...
Published: June, 2021
Abstract: The American lobster, , is integral to marine ecosystems and supports an important commercial fishery. This iconic species also serves as a valuabl... Read more »
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Megaruptor
Epigenetic inheritance of DNA methylation changes in fish living in...
Published: June, 2021
Abstract: Environmental factors can promote phenotypic variation through alterations in the epigenome and facilitate adaptation of an organism to the environ... Read more »
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Antibody
Atg7 deficiency in microglia drives an altered transcriptomic profi...
Published: June, 2021
Abstract: Microglia, resident immunocompetent cells of the central nervous system, can display a range of reaction states and thereby exhibit distinct biolog... Read more »
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iDeal ChIP-qPCR
Analysis of the Coptis chinensis genome reveals the diversification...
Published: June, 2021
Abstract: Chinese goldthread (Coptis chinensis Franch.), a member of the Ranunculales, represents an important early-diverging eudicot lineage with diverse m... Read more »
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Megaruptor
E2F6 initiates stable epigenetic silencing of germline genes during...
Published: June, 2021
Abstract: In mouse development, long-term silencing by CpG island DNA methylation is specifically targeted to germline genes; however, the molecular mechanis... Read more »
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Antibody
Genome-wide CRISPR screen identifies protein pathways modulating ta...
Published: June, 2021
Abstract: Aggregates of hyperphosphorylated tau protein are a pathological hallmark of more than 20 distinct neurodegenerative diseases, including Alzheimer&... Read more »
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Antibody
Environmental enrichment preserves a young DNA methylation landscap...
Published: June, 2021
Abstract: The decline of brain function during aging is associated with epigenetic changes, including DNA methylation. Lifestyle interventions can improve br... Read more »
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Antibody Premium RRBS Kit iDeal ChIP-seq Kit for Transcription Factors
Highly recurrent epimutations in gastric cancer CpG islandmethylat...
Published: June, 2021
Abstract: Background CIMP (CpG island methylator phenotype) is an epigenetic molecular subtype, observed in multiple malignancies and associated with the epi... Read more »
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Antibody
Epigenetic Plasticity Enables CNS-Trafficking of EBV-infectedB Lymp...
Published: June, 2021
Abstract: Subpopulations of B-lymphocytes traffic to different sites and organs to provide diverse and tissue-specific functions. Here, we provide evidence t... Read more »
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MagMeDIP kit
LINE-1 transcription in round spermatids is associated with accreti...
Published: June, 2021
Abstract: Chromatin of male and female gametes undergoes a number of reprogramming events during the transition from germ cell to embryonic developmental pro... Read more »
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Antibody
Infectivity assessment of porcine endogenous retrovirus usinghigh-t...
Published: June, 2021
Abstract: Xenogenic cell-based therapeutic products are expected to alleviate the chronic shortage of human donor organs. For example, porcine islet cell pro... Read more »
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Megaruptor
Lasp1 regulates adherens junction dynamics and fibroblast transform...
Published: June, 2021
Abstract: The LIM and SH3 domain protein 1 (Lasp1) was originally cloned from metastatic breast cancer and characterised as an adaptor molecule associated wi... Read more »
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Antibody IP-Star Compact Microplex Library Preparation kit
Reverse-transcribed SARS-CoV-2 RNA can integrate into the genome of...
Published: May, 2021
Abstract: Prolonged detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA and recurrence of PCR-positive tests have been widely repor... Read more »
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Tagmentase
Small RNAs in Seminal Plasma as Novel Biomarkers for Germ Cell Tumors
Published: May, 2021
Abstract: Circulating miRNAs secreted by testicular germ cell tumors (TGCT) show great potential as novel non-invasive biomarkers for diagnosis of TGCT. Semi... Read more »
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D-Plex small RNA-seq
Vesicle-bound regulatory RNAs are associated with tissue aging
Published: May, 2021
Abstract: Previous work on murine models and human demonstrated global as well as tissue-specific molecular aging trajectories in solid tissues and body flui... Read more »
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D-Plex RNA-seq kit
HOTAIR lncRNA promotes epithelial-mesenchymal transition byredistri...
Published: May, 2021
Abstract: Epithelial-to-mesenchymal transition (EMT) describes the loss of epithelial traits and gain of mesenchymal traits by normal cells during developmen... Read more »
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Antibody
The lncRNA and the transcription factor WRKY42 target common cell ...
Published: May, 2021
Abstract: Plant long noncoding RNAs (lncRNAs) are key chromatin dynamics regulators, directing the transcriptional programs driving a wide variety of develop... Read more »
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Antibody
Placental uptake and metabolism of 25(OH)Vitamin D determines itsac...
Published: May, 2021
Abstract: Pregnancy 25-hydroxyvitamin D (25(OH)D) concentrations are associated with maternal and fetal health outcomes, but the underlying mechanisms have n... Read more »
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Antibody
Chromatin accessibility governs the differential response of cancer...
Published: May, 2021
Abstract: Depleting the microenvironment of important nutrients such as arginine is a key strategy for immune evasion by cancer cells. Many tumors overexpres... Read more »
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Antibody
Sarcomere function activates a p53-dependent DNA damage response th...
Published: May, 2021
Abstract: Human cardiac regeneration is limited by low cardiomyocyte replicative rates and progressive polyploidization by unclear mechanisms. To study this ... Read more »
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Antibody iDeal ChIP-seq Kit for Transcription Factors
Pathophysiological adaptations of resistance arteries in rat offspr...
Published: May, 2021
Abstract: BACKGROUND/OBJECTIVES: Maternal obesity impacts vascular functions linked to metabolic disorders in offspring, leading to cardiovascular diseases d... Read more »
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Premium RRBS Kit DNA Methylation Profiling (RRBS Service)
Small RNAs in Seminal Plasma as Novel Biomarkers for GermCell Tumors.
Published: May, 2021
Abstract: Circulating miRNAs secreted by testicular germ cell tumors (TGCT) show great potential as novel non-invasive biomarkers for diagnosis of TGCT. Semi... Read more »
Tags
D-Plex small RNA-seq
PPARɣ drives IL-33-dependent ILC2 pro-tumoral functions.
Published: May, 2021
Abstract: Group 2 innate lymphoid cells (ILC2s) play a critical role in protection against helminths and in diverse inflammatory diseases by responding to so... Read more »
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Antibody
Contrasting epigenetic control of transgenes and endogenous genespr...
Published: May, 2021
Abstract: Transgenes that are stably expressed in plant genomes over many generations could be assumed to behave epigenetically the same as endogenous genes.... Read more »
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IPure kit
Identification of a PadR-type regulator essential for intracellular...
Published: May, 2021
Abstract: Burkholderia pseudomallei (Bp) is the causative agent of melioidosis, a disease endemic to the tropics. Melioidosis manifests in various ways rangi... Read more »
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Antibody
Epigenomic profiling of primate lymphoblastoid cell lines reveals t...
Published: May, 2021
Abstract: Changes in the epigenetic regulation of gene expression have a central role in evolution. Here, we extensively profiled a panel of human, chimpanze... Read more »
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Antibody
GATA6 defines endoderm fate by controlling chromatin accessibility ...
Published: May, 2021
Abstract: SUMMARY In addition to driving specific gene expression profiles, transcriptional regulators are becoming increasingly recognized for their capacit... Read more »
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Antibody
The SAM domain-containing protein 1 (SAMD1) acts as a repressivechr...
Published: May, 2021
Abstract: CpG islands (CGIs) are key regulatory DNA elements at most promoters, but how they influence the chromatin status and transcription remains elusive... Read more »
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Antibody Microplex Library Preparation kit

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  • 14th International Symposium on Minimal Residual Cancer
    Nice, France
    May 7-May 9, 2025
  • 23rd BioPharma Drug Discovery Nexus
    San Francisco
    May 7-May 8, 2025
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