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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Prenatal detection of aneuploidy and imbalanced chromosomal arrange...
Published: February, 2012
Abstract: Fetal chromosomal abnormalities are the most common reasons for invasive prenatal testing. Currently, G-band karyotyping and several molecular gene... Read more »
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DNA shearing Bioruptor
Transgenerational actions of environmental compounds on reproductiv...
Published: February, 2012
Abstract: Environmental factors during fetal development can induce a permanent epigenetic change in the germ line (sperm) that then transmits epigenetic tra... Read more »
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Antibody
Human Histone Acetyltransferase 1 Protein Preferentially Acetylates...
Published: February, 2012
Abstract: In mammalian cells, canonical histone H3 (H3.1) and H3 variant (H3.3) differ by five amino acids and are assembled, along with histone H4, into nuc... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Protein Arginine Methyltransferase 5 (Prmt5) Promotes Gene Expressi...
Published: February, 2012
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Bioruptor Chromatin Shearing ChIP-qPCR
Transcriptional Activation of the Adenoviral Genome Is Mediated by ...
Published: February, 2012
Abstract: Gene expression of DNA viruses requires nuclear import of the viral genome. Human Adenoviruses (Ads), like most DNA viruses, encode factors within ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
3T3 Cell Lines Stably Expressing Pax6 or Pax6(5a) – A New Tool Used...
Published: February, 2012
Abstract: Pax6 and Pax6(5a) are two isoforms of the evolutionary conserved Pax6 gene often co-expressed in specific stochiometric relationship in the brain a... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Dual-Mode Modulation of Smad Signaling by Smad-Interacting Protein ...
Published: February, 2012
Abstract: Myelination by oligodendrocytes in the central nervous system (CNS) is essential for proper brain function, yet the molecular determinants that con... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Circadian rhythms govern cardiac repolarization and arrhythmogenesis
Published: February, 2012
Abstract: Sudden cardiac death exhibits diurnal variation in both acquired and hereditary forms of heart disease1,2, but the molecular basis of this variatio... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Polycomb repressive complex 2-dependent and -independent functions ...
Published: February, 2012
Abstract: Jarid2 was recently identified as an important component of the mammalian Polycomb Repressive Complex 2 (PRC2), where it has a major effect on PRC2... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Two Cellular Protein Kinases, DNA-PK and PKA, Phosphorylate the Ade...
Published: February, 2012
Abstract: Accumulation of the complex set of alternatively processed mRNA from the adenovirus major late transcription unit (MLTU) is subjected to a temporal... Read more »
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Bioruptor Cell Lysis
Kinetics of DNA methylation inheritance by the Dnmt1-including comp...
Published: February, 2012
Abstract: ABSTRACT: BACKGROUND: The clonal transmission of lineage-specific DNA methylation patterns in a mammalian genome during the cellular division is a ... Read more »
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DNA shearing Bioruptor
Role of Histone Acetylation in the Stimulatory Effect of Valproic A...
Published: February, 2012
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Bioruptor Chromatin Shearing ChIP-qPCR
The Receptor Tyrosine Kinase EphA2 Is a Direct Target Gene of Hyper...
Published: February, 2012
Abstract: The tumor suppressor gene hypermethylated in cancer 1 (HIC1), which encodes a transcriptional repressor, is epigenetically silenced in many human t... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Direct methylation of FXR by Set7/9, a lysine methyltransferase, re...
Published: February, 2012
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Bioruptor Chromatin Shearing ChIP-qPCR
The Origin and Nature of Tightly Clustered BTG1 Deletions in Precur...
Published: February, 2012
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Bioruptor Chromatin Shearing ChIP-qPCR Antibody
The transcription factor Erg controls endothelial cell quiescence b...
Published: February, 2012
Abstract: The interaction of transcription factors with specific DNA sequences is critical for activation of gene expression programmes. In endothelial cells... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
IDH mutation impairs histone demethylation and results in a block t...
Published: February, 2012
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Bioruptor Chromatin Shearing ChIP-qPCR
Opposing Functions of the ETS Factor Family Define Shh Spatial Expr...
Published: February, 2012
Abstract: Sonic hedgehog (Shh) expression during limb development is crucial for specifying the identity and number of digits. The spatial pattern of Shh exp... Read more »
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Bioruptor Chromatin Shearing
Anticheckpoint pathways at telomeres in yeast
Published: February, 2012
Abstract: Telomeres hide (or ‘cap’) chromosome ends from DNA-damage surveillance mechanisms that arrest the cell cycle and promote repair, but the checkpoint... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Antibody
Control of ground-state pluripotency by allelic regulation of Nanog.
Published: February, 2012
Abstract: Pluripotency is established through genome-wide reprogramming during mammalian pre-implantation development, resulting in the formation of the naiv... Read more »
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Antibody H3K4me3 (C15410003)
RHBDF2 mutations are associated with tylosis, a familial esophageal...
Published: February, 2012
Abstract: Tylosis esophageal cancer (TOC) is an autosomal-dominant syndrome characterized by palmoplantar keratoderma, oral precursor lesions, and a high lif... Read more »
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DNA shearing Bioruptor
A workflow for genome-wide mapping of archaeal transcription factor...
Published: February, 2012
Abstract: Deciphering the structure of gene regulatory networks across the tree of life remains one of the major challenges in postgenomic biology. We presen... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Research Resource: The Pdx1 Cistrome of Pancreatic Islets.
Published: February, 2012
Abstract: The homeodomain transcription factor pancreas duodenal homeobox 1 (Pdx1, also known as insulin promoter factor 1) is a master regulator of pancreas... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
RYBP-PRC1 Complexes Mediate H2A Ubiquitylation at Polycomb Target S...
Published: February, 2012
Abstract: Polycomb-repressive complex 1 (PRC1) has a central role in the regulation of heritable gene silencing during differentiation and development. PRC1 ... Read more »
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Bioruptor Chromatin Shearing ChIP-seq Antibody
Dataset integration identifies transcriptional regulation of microR...
Published: February, 2012
Abstract: Peroxisome proliferator-activated receptor γ (PPARγ) is a key transcription factor in mammalian adipogenesis. Genome-wide approaches have identifie... Read more »
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Chromatin Shearing ChIP-qPCR
Hypermethylated in cancer 1 (HIC1) recruits polycomb repressive com...
Published: February, 2012
Abstract: HIC1 (Hypermethylated in Cancer 1) is a tumor suppressor gene epigenetically silenced or deleted in many human cancers. HIC1 is involved in regulat... Read more »
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Chromatin Shearing ChIP-qPCR
High-throughput molecular diagnosis of von Willebrand diseaseby nex...
Published: February, 2012
Abstract: Genetic analysis of von Willebrand disease by von Willebrand factor gene sequencing has not yet become routine practice. Nevertheless, the prospect... Read more »
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DNA shearing Bioruptor
The composition and signaling of the IL-35 receptor are unconventio...
Published: February, 2012
Abstract: Interleukin 35 (IL-35) belongs to the IL-12 family of heterodimeric cytokines but has a distinct functional profile. IL-35 suppresses T cell prolif... Read more »
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Chromatin Shearing ChIP-qPCR
Heritable genome-wide variation of gene expression and promoter met...
Published: February, 2012
Abstract: ABSTRACT: BACKGROUND: Variations in gene expression, mediated by epigenetic mechanisms, may cause broad phenotypic effects in animals. However, it ... Read more »
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Antibody
Three-dimensional folding and functional organization principles of...
Published: February, 2012
Abstract: Chromosomes are the physical realization of genetic information and thus form the basis for its readout and propagation. Here we present a high-res... Read more »
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DNA shearing Bioruptor

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