Diagenode

Mitochondria disruption

2 publications found.

A human pathology-related mutation prevents import of an aminoacyl-tRNA synthetase into mitochondria.
Published: February, 2011

Abstract: Mutations in the nuclear gene coding for the mitochondrial aspartyl-tRNA synthetase, a key enzyme for mitochondrial translation, are correlated with leukoencephalopathy. A Ser⁴⁵ to Gly⁴⁵ mutation is located in the predicted targeting signal of the...
Read more »

Novel isoenzyme of 2-oxoglutarate dehydrogenase is identified in brain, but not in heart.
Published: October, 2008

Abstract: 2-Oxoglutarate dehydrogenase (OGDH) is the first and rate-limiting component of the multienzyme OGDH complex (OGDHC) whose malfunction is associated with neurodegeneration. The essential role of this complex in the degradation of glucose and gluta...
Read more »

Events

 See all events

Applications

 See all applications



The European Regional Development Fund and Wallonia are investing in your future.

Extension of industrial buildings and new laboratories.



  ABOUT SSL CERTIFICATES

         Site map   |   Contact us   |   Conditions of sales   |   Conditions of purchase   |   Privacy policy   |   Diagenode Diagnostics