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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

An endosiRNA-Based Repression Mechanism Counteracts Transposon Acti...
Published: November, 2017
Abstract: Erasure of DNA methylation and repressive chromatin marks in the mammalian germline leads to risk of transcriptional activation of transposable ele... Read more »
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Microplex Library Preparation kit
Transcription Factor YY1 Modulates Lung Cancer Progression by Activ...
Published: November, 2017
Abstract: Lung cancer is the leading cause of cancer-related death worldwide. Despite the advancement in surgery and chemotherapy, the prognosis of patients ... Read more »
Epigenetic control of epilepsy target genes contributes to a cellul...
Published: October, 2017
Abstract: Hypersynchronous neuronal excitation manifests clinically as seizure (ictogenesis), and may recur spontaneously and repetitively after a variable l... Read more »
Drug-tunable multidimensional synthetic gene control using inducibl...
Published: October, 2017
Abstract: The nuclease-deactivated variant of CRISPR-Cas9 proteins (dCas9) fused to heterologous transactivation domains can act as a potent guide RNA sequen... Read more »
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Antibody
Saliva as a Blood Alternative for Genome-Wide DNA Methylation Profi...
Published: October, 2017
Abstract: Background: Interrogation of DNA methylation profiles hold promise for improved diagnostics, as well as the delineation of the aetiology for common... Read more »
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IP-Star Compact
Alterations in the placental methylome with maternal obesity and ev...
Published: October, 2017
Abstract: The inflammatory and metabolic derangements of obesity in pregnant women generate an adverse intrauterine environment, increase pregnancy complicat... Read more »
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Antibody
Single-Molecule Sequencing Reveals the Chromosome-Scale Genomic Arc...
Published: October, 2017
Abstract: The nematode Pristionchus pacificus is an established model for integrative evolutionary biology and comparative studies with Caenorhabditis elegan... Read more »
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Megaruptor
Nuclear and Mitochondrial DNA Methylation Patterns Induced by Valpr...
Published: October, 2017
Abstract: Valproic acid (VPA) is one of the most widely prescribed antiepileptic drugs in the world. Despite its pharmacological importance, it may cause liv... Read more »
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MagMeDIP kit IPure kit
Individual effects of the copia and gypsy enhancer and insulator on...
Published: October, 2017
Abstract: Enhancers and insulators are involved in the regulation of gene expression, but the basic underlying mechanisms of action of these elements are unk... Read more »
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ChIP-qPCR
Distinguishing States of Arrest: Genome-Wide Descriptions of Cellul...
Published: October, 2017
Abstract: Regenerative potential in adult stem cells is closely associated with the establishment of-and exit from-a temporary state of quiescence. Emerging ... Read more »
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LowCell ChIP kit IPure kit
Genome methylation and regulatory functions for hypoxic adaptation...
Published: October, 2017
Abstract: Tibetan chickens have unique adaptations to the extreme high-altitude environment that they inhabit. Epigenetic DNA methylation affects many biolog... Read more »
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MagMeDIP kit
Discovery of a selective catalytic p300/CBP inhibitor that targets ...
Published: October, 2017
Abstract: The dynamic and reversible acetylation of proteins, catalysed by histone acetyltransferases (HATs) and histone deacetylases (HDACs), is a major epi... Read more »
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Bioruptor IP-Star Compact
The Role of N-α-acetyltransferase 10 Protein in DNA Methylation and...
Published: October, 2017
Abstract: Genomic imprinting is an allelic gene expression phenomenon primarily controlled by allele-specific DNA methylation at the imprinting control regio... Read more »
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Antibody
The mixed lineage leukemia 4 (MLL4) methyltransferase complex is in...
Published: October, 2017
Abstract: Sma and Mad related (SMAD)-mediated Transforming Growth Factor β (TGF-β) and Bone Morphogenetic Protein (BMP) signaling is required for v... Read more »
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Antibody
De novo PacBio long-read and phased avian genome assemblies correct...
Published: October, 2017
Abstract: Reference-quality genomes are expected to provide a resource for studying gene structure, function, and evolution. However, often genes of interest... Read more »
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Megaruptor
BET-bromodomain inhibitors modulate epigenetic patterns at the diac...
Published: October, 2017
Abstract: BACKGROUND AND PURPOSE: Fibrosis is a frequent adverse effect of radiotherapy and no effective treatments are currently available to prevent or re... Read more »
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IP-Star Compact
Rapid Communication: The correlation between histone modifications ...
Published: October, 2017
Abstract: Histone modification is a well-known epigenetic mechanism involved in regulation of gene expression; however, it has been poorly studied in adipose... Read more »
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Antibody LowCell ChIP kit
TET2- and TDG-mediated changes are required for the acquisition of ...
Published: September, 2017
Abstract: The plasticity of myeloid cells is illustrated by a diversity of functions including their role as effectors of innate immunity as macrophages (MAC... Read more »
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Antibody LowCell ChIP kit
Genomic imprinting of Xist by maternal H3K27me3
Published: September, 2017
Abstract: Maternal imprinting at the Xist gene is essential to achieve paternal allele-specific imprinted X-chromosome inactivation (XCI) in female mammals. ... Read more »
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H3K27me3 (C15410069)
Predicting stimulation-dependent enhancer-promoter interactions fro...
Published: September, 2017
Abstract: We have developed a machine learning approach to predict stimulation-dependent enhancer-promoter interactions using evidence from changes in genomi... Read more »
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Antibody
In trans paired nicking triggers seamless genome editing without do...
Published: September, 2017
Abstract: Precise genome editing involves homologous recombination between donor DNA and chromosomal sequences subjected to double-stranded DNA breaks made b... Read more »
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Antibody
Reproducibility of methylated CpG typing with the Illumina MiSeq
Published: September, 2017
Abstract: DNA methylation patterns may be used for identification of body fluids and for age estimation of human individuals. We evaluated some of the chal... Read more »
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Premium Bisulfite Kit
CDK8/19 Mediator kinases potentiate induction of transcription by NFκB
Published: September, 2017
Abstract: The nuclear factor-κB (NFκB) family of transcription factors has been implicated in inflammatory disorders, viral infections, and cance... Read more »
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Antibody
Histone H4K20 tri-methylation at late-firing origins ensures timely...
Published: September, 2017
Abstract: Among other targets, the protein lysine methyltransferase PR-Set7 induces histone H4 lysine 20 monomethylation (H4K20me1), which is the substrate f... Read more »
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Antibody
UV Radiation Activates Toll-Like Receptor 9 Expression in Primary H...
Published: September, 2017
Abstract: Several lines of evidence indicate that cutaneous human papillomavirus (HPV) types belonging to the beta genus of the HPV phylogenetic tree synergi... Read more »
5-hydroxymethylcytosine accumulation in postmitotic neurons results...
Published: September, 2017
Abstract: 5-hydroxymethylcytosine (5hmC) occurs at maximal levels in postmitotic neurons, where its accumulation is cell-specific and correlated with gene ex... Read more »
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LowCell ChIP kit
Genetic Predisposition to Multiple Myeloma at 5q15 Is Mediated by a...
Published: September, 2017
Abstract: Multiple myeloma (MM) is a malignancy of plasma cells. Genome-wide association studies have shown that variation at 5q15 influences MM risk. Here, ... Read more »
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IP-Star Antibody
MYC drives overexpression of telomerase RNA (hTR/TERC) in prostate ...
Published: September, 2017
Abstract: Telomerase consists of at least two essential elements, an RNA component hTR or TERC that contains the template for telomere DNA addition and a cat... Read more »
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ChIP-qPCR
The cardiac calsequestrin gene transcription is modulated at the pr...
Published: September, 2017
Abstract: Calsequestrin-2 (CASQ2) is the main Ca2+-binding protein inside the sarcoplasmic reticulum of cardiomyocytes. Previously, we demonstrated that MEF-... Read more »
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ChIP-seq
The cardiac calsequestrin gene transcription is modulated at the pr...
Published: September, 2017
Abstract: Calsequestrin-2 (CASQ2) is the main Ca2+-binding protein inside the sarcoplasmic reticulum of cardiomyocytes. Previously, we demonstrated that MEF-... Read more »

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  • 14th International Symposium on Minimal Residual Cancer
    Nice, France
    May 7-May 9, 2025
  • 23rd BioPharma Drug Discovery Nexus
    San Francisco
    May 7-May 8, 2025
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