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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Loss of Rb proteins causes genomic instability in the absence of mi...
Published: July, 2010
Abstract: Loss of G1/S control is a hallmark of cancer, and is often caused by inactivation of the retinoblastoma pathway. However, mouse embryonic fibroblas... Read more »
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DNA shearing Bioruptor
Aryl hydrocarbon receptor and NF-E2-related factor 2 are key regula...
Published: July, 2010
Abstract: Multidrug resistance protein 4 (MRP4; ABCC4) is an ATP binding cassette transporter that facilitates the excretion of bile salt conjugates and othe... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
The impact of intragenic CpG content on gene expression.
Published: July, 2010
Abstract: The development of vaccine components or recombinant therapeutics critically depends on sustained expression of the corresponding transgene. This s... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Roles of COMM-domain-containing 1 in stability and recruitment of t...
Published: July, 2010
Abstract: A novel function of COMMD1 {COMM [copper metabolism MURR1 (mouse U2af1-rs1 region 1)]-domain-containing 1}, a protein relevant to canine copper tox... Read more »
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Cell Lysis
Use of Illumina sequencing to identify transposon insertions underl...
Published: July, 2010
Abstract: High-copy transposons have been effectively exploited as mutagens in a variety of organisms. However, their utility for phenotype-driven forward ge... Read more »
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DNA shearing Bioruptor
The HOX Code as a "biological fingerprint" to distinguish functiona...
Published: July, 2010
Abstract: Mesenchymal stem cells (MSC) have been isolated from almost every adult tissue. In cord blood (CB), different non-hematopoietic CD45-, CD34- adhere... Read more »
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MeDIP kit
The bHLH transcription factor POPEYE regulates response to iron def...
Published: July, 2010
Abstract: Global population increases and climate change underscore the need for better comprehension of how plants acquire and process nutrients such as iro... Read more »
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Bioruptor Chromatin Shearing
Genome-wide profiling of interleukin-4 and STAT6 transcription fact...
Published: June, 2010
Abstract: Dissecting the molecular mechanisms by which T helper (Th) cells differentiate to effector Th2 cells is important for understanding the pathogenesi... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
A gene-specific requirement of RNA polymerase II CTD phosphorylatio...
Published: June, 2010
Abstract: BACKGROUND: The switch from cellular proliferation to differentiation occurs to a large extent through specific programs of gene expression. In fis... Read more »
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Bioruptor Chromatin Shearing
Vertebrate homologue of Drosophila GAGA factor.
Published: June, 2010
Abstract: Polycomb group (PcG) and trithorax group (trxG) proteins are chromatin-mediated regulators of a number of developmentally important genes including... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
A simple method for gene expression and chromatin profiling of indi...
Published: June, 2010
Abstract: Understanding the production and function of specialized cells during development requires the isolation of individual cell types for analysis, but... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Chromatin-Remodeling Components of the BAF Complex Facilitate Repro...
Published: June, 2010
Abstract: Reprogramming of somatic cells achieved by combination of the four transcription factors Oct4, Sox2, Klf4, and c-Myc has very low efficiency. To in... Read more »
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LowCell ChIP kit
Regulation of cyclin B2 expression and cell cycle G2/m transition b...
Published: June, 2010
Abstract: Multiple endocrine neoplasia type 1 (MEN1) results from mutations in tumor suppressor gene Men1, which encodes nuclear protein menin. Menin up-regu... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Th2 LCR is essential for regulation of Th2 cytokine genes and for p...
Published: June, 2010
Abstract: Previous studies have shown that Th2 cytokine genes on mouse chromosome 11 are coordinately regulated by the Th2 locus control region (LCR). To exa... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
ESCs require PRC2 to direct the successful reprogramming of differe...
Published: June, 2010
Abstract: Embryonic stem cells (ESCs) are pluripotent, self-renewing, and have the ability to reprogram differentiated cell types to pluripotency upon cellul... Read more »
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Antibody
A murine ESC-like state facilitates transgenesis and homologous rec...
Published: June, 2010
Abstract: Murine pluripotent stem cells can exist in two functionally distinct states, LIF-dependent embryonic stem cells (ESCs) and bFGF-dependent epiblast ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Promoter demethylation and chromatin remodeling by green tea polyph...
Published: June, 2010
Abstract: Epigenetic silencing of gluthathione-S-transferase pi (GSTP1) is recognized as being a molecular hallmark of human prostate cancer. We investigated... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
CDKL5 is a brain MeCP2 target gene regulated by DNA methylation.
Published: June, 2010
Abstract: Rett syndrome and its "early-onset seizure" variant are severe neurodevelopmental disorders associated with mutations within the MECP2 and the CDKL... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Estrogen-mediated epigenetic repression of large chromosomal region...
Published: June, 2010
Abstract: The current concept of epigenetic repression is based on one repressor unit corresponding to one silent gene. This notion, however, cannot adequate... Read more »
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DNA shearing Chromatin Shearing ChIP-qPCR ChIP-seq Antibody 5mC (C15200081)
Transcriptional regulation of endochondral ossification by HIF-2alp...
Published: June, 2010
Abstract: Chondrocyte hypertrophy followed by cartilage matrix degradation and vascular invasion, characterized by expression of type X collagen (COL10A1), m... Read more »
Illumina sequencing library preparation for highly multiplexed targ...
Published: June, 2010
Abstract: The large amount of DNA sequence data generated by high-throughput sequencing technologies often allows multiple samples to be sequenced in paralle... Read more »
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DNA shearing Bioruptor
Accumulation of piRNAs in the chromatoid bodies purified by a novel...
Published: May, 2010
Abstract: Haploid male germ cells are featured by an intriguing cytoplasmic cloud-like structure that has been named as chromatoid body (CB) on the basis of ... Read more »
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Bioruptor Cell Lysis
Dual roles of smad proteins in the conversion from myoblasts to ost...
Published: May, 2010
Abstract: Bone morphogenetic proteins (BMPs) induce ectopic bone formation in muscle tissue in vivo and convert myoblasts such that they differentiate into o... Read more »
Altered histone acetylation is associated with age-dependent memory...
Published: May, 2010
Abstract: As the human life span increases, the number of people suffering from cognitive decline is rising dramatically. The mechanisms underlying age-assoc... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Materials and Methods - Altered histone acetylation is associated w...
Published: May, 2010
Abstract: As the human life span increases, the number of people suffering from cognitive decline is rising dramatically. The mechanisms underlying age-assoc... Read more »
FOXO3A as a key molecule for all-trans retinoic acid-induced granul...
Published: May, 2010
Abstract: All-trans retinoic acid (ATRA) induces granulocytic differentiation and apoptosis in acute promyelocytic leukemia (APL) cells, although the detaile... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
det1-1-induced UV-C hyposensitivity through UVR3 and PHR1 photolyas...
Published: May, 2010
Abstract: Summary Obligate photoautotrophs such as plants must capture energy from sunlight and are therefore exposed to the damaging collateral effects of u... Read more »
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Antibody
Cooperation between the transcription factors p63 and IRF6 is essen...
Published: May, 2010
Abstract: Cleft palate is a common congenital disorder that affects up to 1 in 2,500 live human births and results in considerable morbidity to affected indi... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Repression of transcriptional activity of C/EBPalpha by E2F-dimeriz...
Published: May, 2010
Abstract: The transcription factor CCAAT/enhancer-binding protein alpha (C/EBPalpha) coordinates proliferation arrest and the differentiation of myeloid prog... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Profiling of promoter occupancy by PPARalpha in human hepatoma cell...
Published: May, 2010
Abstract: The transcription factor peroxisome proliferator-activated receptor alpha (PPARalpha) is an important regulator of hepatic lipid metabolism. While ... Read more »
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Bioruptor Chromatin Shearing

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