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Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

Phosphorylated and small ubiquitin-like modifier protein-deficient ...
Published: June, 2012

Abstract: ABSTRACT: INTRODUCTION: Progesterone receptors (PR) are emerging as important breast cancer drivers. Phosphorylation events common to breast cancer... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Cardioprotective mIGF-1/SIRT1 signaling induces hypertension, leuko...
Published: June, 2012

Abstract: Locally acting insulin growth factor isoform (mIGF-1) and the NAD+-dependent protein deacetylase SIRT1 are implicated in life and health span. Hear... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Functional characterization of the promoter region of the human EVI...
Published: June, 2012

Abstract: The EVI1 gene (3q26) codes for a transcription factor with important roles in normal hematopoiesis and leukemogenesis. High expression of EVI1 is a... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Whole-Exome Sequencing and High Throughput Genotyping Identified KC...
Published: June, 2012

Abstract: BACKGROUND: Maturity-onset of the young (MODY) is a clinically heterogeneous form of diabetes characterized by an autosomal-dominant mode of inheri... Read more »

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DNA shearing Bioruptor

RNA Polymerase II Pausing Downstream of Core Histone Genes Is Diffe...
Published: June, 2012

Abstract: Recent genome-wide chromatin immunoprecipitation coupled high throughput sequencing (ChIP-seq) analyses performed in various eukaryotic organisms, ... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Genome-Wide DNA Methylation Changes between the Superficial and Dee...
Published: June, 2012

Abstract: Read more »

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DNA shearing Bioruptor Antibody

Phosphorylation of p65(RelA) on Ser547 by ATM Represses NF-κB-Depen...
Published: June, 2012

Abstract: Read more »

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Antibody

The histone H2B monoubiquitination regulatory pathway is required f...
Published: June, 2012

Abstract: Extensive changes in posttranslational histone modifications accompany the rewiring of the transcriptional program during stem cell differentiation... Read more »

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Antibody H3K4me3 (C15410003) H3K27me3 (C15410069)

Genome-wide localization and expression profiling establish Sp2 as ...
Published: June, 2012

Abstract: The transcription factor Sp2 is essential for early mouse development and for proliferation of mouse embryonic fibroblasts in culture. Yet its mech... Read more »

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Antibody

Recruitment of histone deacetylase 3 to the interferon-a gene promo...
Published: June, 2012

Abstract: BACKGROUND: Induction of Type I Interferon (IFN) genes constitutes an essential step leading to innate immune responses during virus infection. Sen... Read more »

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Antibody

Transcriptional networks driving enhancer function in the CFTR gene.
Published: June, 2012

Abstract: A critical cis-regulatory element for the cystic fibrosis transmembrane conductance regulator (CFTR) gene is located in intron 11, 100 kb distal to... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus

GSK3 Temporally Regulates Neurogenin 2 Proneural Activity in the Ne...
Published: June, 2012

Abstract: The neocortex is comprised of six neuronal layers that are generated in a defined temporal sequence. While extrinsic and intrinsic cues are known t... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Developmentally non-redundant SET domain proteins SUVH2 and SUVH9 a...
Published: June, 2012

Abstract: In plants, RNA-directed DNA methylation (RdDM) and related transcriptional gene silencing (TGS) involve members of the suppressor of variegation 3-... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Genomics of DNA cytosine methylation in Escherichia coli reveals it...
Published: June, 2012

Abstract: DNA cytosine methylation regulates gene expression in mammals. In bacteria, its role in gene expression and genome architecture is less understood.... Read more »

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DNA shearing Bioruptor

Intronic RNAs mediate EZH2 regulation of epigenetic targets.
Published: June, 2012

Abstract: Epigenetic deregulation at a number of genomic loci is one of the hallmarks of cancer. A role for some RNA molecules in guiding repressive polycomb... Read more »

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Antibody LowCell ChIP kit H3K4me3 (C15410003) H3K27me3 (C15410069)

PGC7 binds histone H3K9me2 to protect against conversion of 5mC to ...
Published: June, 2012

Abstract: Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

SUMO-targeted ubiquitin E3 ligase RNF4 is required for the response...
Published: June, 2012

Abstract: Here we demonstrate that RNF4, a highly conserved small ubiquitin-like modifier (SUMO)-targeted ubiquitin E3 ligase, plays a critical role in the r... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

FOXO1 in the ventromedial hypothalamus regulates energy balance.
Published: June, 2012

Abstract: The transcription factor FOXO1 plays a central role in metabolic homeostasis by regulating leptin and insulin activity in many cell types, includin... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Histone H2B Ubiquitylation Promotes Activity of the Intact Set1 His...
Published: June, 2012

Abstract: The methylation of histone H3 at lysine 4 (H3K4me) is critical for the formation of transcriptionally active chromatin in eukaryotes. In yeast, Dro... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Genome structure-based screening identified epigenetically silenced...
Published: June, 2012

Abstract: MicroRNA (miRNA) expression is frequently altered in human cancers. To search for epigenetically silenced miRNAs in non-small-cell lung cancer (NSC... Read more »

Preferential Genome Targeting of the CBP Co-Activator by Rel and Sm...
Published: June, 2012

Abstract: CBP and the related p300 protein are widely used transcriptional co-activators in metazoans that interact with multiple transcription factors. Whet... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Overexpression of HGF attenuates the degeneration of Purkinje cells...
Published: June, 2012

Abstract: Spinocerebellar ataxia type 7 (SCA7) is an autosomal dominant disorder associated with cerebellar neurodegeneration caused by expansion of a CAG re... Read more »

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Tissue Homogenization

Multiple Histone Methyl and Acetyltransferase Complex Components Bi...
Published: May, 2012

Abstract: Major histocompatibility complex class II (MHC-II) genes are fundamental components that contribute to adaptive immune responses. While characteriz... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Serum Response Factor and cAMP Response Element Binding Protein Are...
Published: May, 2012

Abstract: The molecular mechanism underlying induction by cocaine of ΔFosB, a transcription factor important for addiction, remains unknown. Here, we demonst... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Disruptive cell cycle regulation involving epigenetic downregulatio...
Published: May, 2012

Abstract: Cell cycle aberration was immunohistochemically examined in relation to preneoplastic liver cell foci expressing glutathione S-transferase placenta... Read more »

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DNA shearing MeDIP kit

Genome-Wide Characterization of Menin-Dependent H3K4me3 Reveals a S...
Published: May, 2012

Abstract: Inactivating mutations in the MEN1 gene predisposing to the multiple endocrine neoplasia type 1 (MEN1) syndrome can also cause sporadic pancreatic ... Read more »

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Bioruptor Chromatin Shearing ChIP-seq

Myb-binding protein 1a (Mybbp1a) regulates levels and processing of...
Published: May, 2012

Abstract: Ribosomal RNA gene transcription, co-transcriptional processing and ribosome biogenesis are highly coordinated processes that are tightly regulated... Read more »

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Bioruptor

Mus81-Mms4 function as a single heterodimer to cleave nicked interm...
Published: May, 2012

Abstract: The formation of crossovers is a fundamental genetic process. The XPF-family endonuclease, Mus81-Mms4 (Eme1), contributes significantly to crossing... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

The aryl hydrocarbon receptor ligands 2,3,7,8-tetrachlorodibenzo-p-...
Published: May, 2012

Abstract: The two estrogen receptor isoforms ERα and ERβ mediate biological effects of estrogens, but are also targets for endocrine disruptive chemicals (ED... Read more »

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Bioruptor Chromatin Shearing ChIP-qPCR

Design, Synthesis, and Biological Evaluation of 2-Aminobenzanilide ...
Published: May, 2012

Abstract: Epigenetic regulation is an essential process for the normal functioning of genes. Therefore, targeting epigenetic dysregulation in cancer may be a... Read more »

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Antibody

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