Activity Test - Procedure for immunoprecipitation of native chromatin proteins

Proteins play role in almost all cellular processes, and the study of their activity is crucial for understanding these mechanisms. Slimane AIT-SI-ALI and his “epigenetics and cell fate” team from the University Paris Descartes developed a protocol allowing the immunoprecipitation of chromatin proteins prior the analysis of their activity. They used the Bioruptor® in the initial step of the procedure to release this specific protein, which is advantageous in preserving protein quality.

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