A Rapid and Robust Protocol for Reduced Representation Bisulfite Sequencing in Multiple Myeloma. Choudhury SR, Walker BA Reduced representation bisulfite sequencing (RRBS) is one of the most comprehensive yet economic ways of mapping whole genome DNA-methylation. Here, we have substantially modified the RRBS protocol by combining end-repair and A-tailing steps, and by introducing a bead-based method for rapid and easy size selection o...
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