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Publications

Explore Diagenode’s publication database. Learn how our products are used in diverse fields of research.

DNA Copy-Number Control through Inhibition of Replication Fork Prog...
Published: November, 2014
Abstract: Proper control of DNA replication is essential to ensure faithful transmission of genetic material and prevent chromosomal aberrations that can dri... Read more »
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Bioruptor Chromatin Shearing ChIP-seq Bioruptor Plus
Silica nanoparticles induce autophagy and endothelial dysfunction v...
Published: November, 2014
Abstract: Although nanoparticles have a great potential for biomedical applications, there is still a lack of a correlative safety evaluation on the cardiova... Read more »
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Bioruptor
The repair of oxidized purines in the DNA of human lymphocytes requ...
Published: November, 2014
Abstract: 8-Oxoguanine DNA glycosylase (OGG1), which initiates the repair of DNA purine modifications such as 8-oxo-7,8-dihydroguanine (8-oxoG), is often reg... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus
A phylogenomic analysis of turtles.
Published: November, 2014
Abstract: Molecular analyses of turtle relationships have overturned prevailing morphological hypotheses and prompted the development of a new taxonomy. Here... Read more »
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DNA shearing Bioruptor
The LXR-Idol Axis Differentially Regulates Plasma LDL Levels in Pri...
Published: November, 2014
Abstract: The LXR-regulated E3 ubiquitin ligase IDOL controls LDLR receptor stability independent of SREBP and PCSK9, but its relevance to plasma lipid level... Read more »
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Master Mix
A variably occupied CTCF binding site in the Ultrabithorax gene in ...
Published: November, 2014
Abstract: Although the majority of genomic binding sites for the insulator protein CTCF are constitutively occupied, a subset show variably occupancy. Such v... Read more »
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Bioruptor Chromatin Shearing
Detection of single nucleotide polymorphisms in Plasmodium falcipar...
Published: November, 2014
Abstract: Resistance of Plasmodium falciparum to some antimalarial drugs is linked to single nucleotide polymorphisms (SNPs). Currently there are no methods ... Read more »
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Bioruptor
Deregulation of Rb-E2F1 axis causes chromosomal instability by enga...
Published: November, 2014
Abstract: E2F family of transcription factors regulate genes involved in various aspects of cell cycle. Beyond the well-documented role in G1/S transition, m... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
A Novel Mouse Model for the Hyper-IgM Syndrome: A Spontaneous Activ...
Published: November, 2014
Abstract: We describe a spontaneously derived mouse line that completely failed to induce Ig class switching in vitro and in vivo. The mice inherited abolish... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus
Continuous requirement for the TCR in regulatory T cell function.
Published: November, 2014
Abstract: Foxp3(+) regulatory T cells (Treg cells) maintain immunological tolerance, and their deficiency results in fatal multiorgan autoimmunity. Although ... Read more »
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Bioruptor
Genome-wide identification of signaling center enhancers in the dev...
Published: November, 2014
Abstract: The limb is widely used as a model developmental system and changes to gene expression patterns in its signaling centers, notably the zone of polar... Read more »
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LowCell ChIP kit
Blocking of JB6 Cell Transformation by Tanshinone IIA: Epigenetic R...
Published: November, 2014
Abstract: Increasing numbers of natural products have been found to possess anticancer effects. Nuclear factor erythroid-2-related factor-2 (Nrf2) is a maste... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Characterization of microsatellite markers for pinedrops, Pterospor...
Published: November, 2014
Abstract: UNLABELLED: • PREMISE OF THE STUDY: Pterospora andromedea (Ericaceae) is a mycoheterotrophic plant endemic to North America with a disjunct distrib... Read more »
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DNA shearing Bioruptor
RNA Processing Factors Swd2.2 and Sen1 Antagonize RNA Pol III-Depen...
Published: November, 2014
Abstract: Condensin-mediated chromosome condensation is essential for genome stability upon cell division. Genetic studies have indicated that the associatio... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Progestin and antiprogestin responsiveness in breast cancer is driv...
Published: November, 2014
Abstract: There is emerging interest in understanding the role of progesterone receptors (PRs) in breast cancer. The aim of this study was to investigate the... Read more »
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HighCell ChIP kit
Genome-wide identification of aberrantly methylated promoters in ov...
Published: November, 2014
Abstract: OBJECTIVE: To identify aberrantly methylated candidate genes that are involved in the development of polycystic ovary syndrome (PCOS). DESIGN: Anim... Read more »
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DNA shearing Bioruptor Antibody
Epstein-Barr virus nuclear antigen 3A protein regulates CDKN2B tran...
Published: November, 2014
Abstract: The Epstein-Barr virus (EBV) nuclear antigen 3 family of protein is critical for the EBV-induced primary B-cell growth transformation process. Usin... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Synthetic secondary chromosomes in Escherichia coli based on the re...
Published: October, 2014
Abstract: Recent developments in DNA-assembly methods make the synthesis of synthetic chromosomes a reachable goal. However, the redesign of primary chromoso... Read more »
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DNA shearing Bioruptor
IL-6, IL-8, MMP-2, MMP-9 are overexpressed in Fanconi anemia cells ...
Published: October, 2014
Abstract: Fanconi anemia (FA) is a rare autosomal recessive genetic disorder associated with a bone-marrow failure, genome instability, hypersensitivity to D... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Ultrasensitive proteome analysis using paramagnetic bead technology.
Published: October, 2014
Abstract: In order to obtain a systems-level understanding of a complex biological system, detailed proteome information is essential. Despite great progress... Read more »
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Bioruptor Cell Lysis
Androgen receptor-interacting protein HSPBAP1 facilitates growth of...
Published: October, 2014
Abstract: Hormonal therapies targeting androgen receptor (AR) are effective in prostate cancer (PCa), but often the cancers progress to fatal castrate-resist... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus
Enantioselective regulation of lactate racemization by LarR in Lact...
Published: October, 2014
Abstract: Lactobacillus plantarum is a lactic acid bacterium that produces a racemic mixture of L- and D-lactate from sugar fermentation. The inter-conversio... Read more »
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Bioruptor Cell Lysis
Loss of Nucleolar Histone Chaperone NPM1 Triggers Rearrangement of ...
Published: October, 2014
Abstract: Nucleoli are prominent nuclear structures assembled and organized around actively transcribed ribosomal DNA (rDNA). The nucleolus has emerged as a ... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR Bioruptor Plus
BET bromodomain inhibition suppresses transcriptional responses to ...
Published: October, 2014
Abstract: Disruption of the interaction of bromo and extraterminal (BET) proteins with acetylated histones using small molecule inhibitors suppresses Myc-dri... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
Zinc finger protein Zfp335 is required for the formation of the naï...
Published: October, 2014
Abstract: The generation of naïve T lymphocytes is critical for immune function yet the mechanisms governing their maturation remain incompletely understood.... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Epigenetic regulation of inflammatory gene expression in macrophage...
Published: October, 2014
Abstract: Acetylation of histone and non-histone proteins by histone acetyltransferases plays a pivotal role in the expression of proinflammatory genes. Give... Read more »
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Bioruptor Chromatin Shearing ChIP-qPCR
A B-cell targeting virus disrupts potentially protective genomic me...
Published: October, 2014
Abstract: The mechanisms by which viruses modulate the immune system include changes in host genomic methylation. 5-hydroxmethylcytosine (5hmC) is the cataly... Read more »
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Antibody 5mC (C15200081)
AF9 YEATS Domain Links Histone Acetylation to DOT1L-Mediated H3K79 ...
Published: October, 2014
Abstract: The recognition of modified histones by "reader" proteins constitutes a key mechanism regulating gene expression in the chromatin context. Compared... Read more »
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Bioruptor Chromatin Shearing ChIP-seq
Precision microbiome reconstitution restores bile acid mediated res...
Published: October, 2014
Abstract: The gastrointestinal tracts of mammals are colonized by hundreds of microbial species that contribute to health, including colonization resistance ... Read more »
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Bioruptor Cell Lysis Mass Spectrometry
Next Generation Sequencing Identifies a Novel Rearrangement in the ...
Published: October, 2014
Abstract: Genetic testing for hemoglobinopathies is required for prenatal diagnosis, understanding complex cases where multiple pathogenic variants may be pr... Read more »
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DNA shearing Bioruptor

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